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pro vyhledávání: '"William Golde"'
Infection with foot-and-mouth disease virus induces a natural killer cell response in cattle (P6080)
Publikováno v:
The Journal of Immunology. 190:141.7-141.7
Natural killer (NK) cells play an important role in innate immune defense against viral diseases. Although they develop from the same lymphoid precursor cells as B and T lymphocytes, NK cells lack an antigen specific receptor, and are regulated in an
Autor:
Lasse Pedersen, Michael Rasmussen, Mikkel Harndah, Jared Patch, Morten Nielsen, Soren Buus, William Golde, Gregers Jungersen
Publikováno v:
The Journal of Immunology. 190:141.13-141.13
The affinity with which major histocompatibility complex (MHC) class I molecules bind peptides is instrumental to presentation of viral epitopes to cytotoxic T lymphocytes (CTLs). We analyzed three swine leukocyte antigen (SLA) molecules for complete
Publikováno v:
The Journal of Immunology. 190:141.16-141.16
Bovine γδ T cells have properties of both innate and adaptive immune cells. However, detailed studies of how bovine γδ T cells execute their functions as innate or adaptive immune cells are lacking. In addition, their precise role in viral infect
Autor:
Pervaiz Dar, Jared Patch, Mary Kenney, Ryan Waters, Raisa Glabman, Ganesh Kondabattulla, William Golde
Publikováno v:
The Journal of Immunology. 188:181.2-181.2
Bovine natural killer (NK) cells are important mediators of the innate immune response to infectious diseases of cattle. Like other mammalian species, bovine NK cells express NKp46 (CD335) and do not express CD3 or a T cell receptor. However, bovine
Autor:
Jared Patch, Lasse Pedersen, Mary Kenney, Juan Pacheco, Raisa Glabman, Mital Pandya, Morten Nielsen, Soren Buus, William Golde
Publikováno v:
The Journal of Immunology. 186:170.14-170.14
Foot-and-mouth disease (FMD) is a disease of cloven-hoofed animals that remains a threat to the livestock industry. FMD virus (FMDV) causes an acute infection characterized by fever and the formation of vesicles on the feet and tongue. This picornavi
Publikováno v:
The Journal of Immunology. 184:43.10-43.10
Foot-and-mouth disease virus (FMDV) is a highly infectious picornavirus that causes disease in cloven-hoofed animals. Neutralizing antibodies are thought to play a primary role in FMDV immunity, and their induction forms the basis for current vaccine
Autor:
Mital Pandya, Elizabeth Bishop, Juan Pacheco, Charles Scherer, Francis Milward, Timothy Doel, William Golde
Publikováno v:
The Journal of Immunology. 184:43.15-43.15
Foot-and-mouth disease virus (FMDV) is a highly infectious disease of cloven-hoofed animals, with severe agricultural and economic implications. The standard needle inoculation method is not the most efficient system of swiftly vaccinating large numb
Publikováno v:
The Journal of Immunology. 184:43.2-43.2
Toll like receptors (TLRs) play a critical role in the immediate detection and control of infection in mammals and are important for initiating a series of signaling events which result in proinflammatory gene expression. Many of these receptors are
Publikováno v:
The Journal of Immunology. 184:43.16-43.16
To date, little is known about the binding specificities for Swine Leukocyte Antigens (SLA) compared to the enormous amount of data available for the Human Leukocyte Antigens (HLA). The increase in immunology and infectious disease research using pig
Publikováno v:
The Journal of Immunology. 182:81.2-81.2
Natural Killer cells (NK) are important in both antiviral, bacterial and tumor defense and constitute a major effector population of the innate immune defense. Activation of NK cells by specific cell surface expressed proteins in infected or tumor ce