Výsledky vyhledávání - "William G. Starkey"

Nucleotide sequence analysis of a major antigenic domain of the E1 glycoprotein of 22 rubella virus isolates

Autor: K. M. Corbett, Jangu E. Banatvala, William G. Starkey, J. M. Best, T J Bosma

Publikováno v: Journal of General Virology. 77:2523-2530

We have determined the nucleotide sequence of the region of the rubella virus genome which encodes amino acids 195-296 of the E1 glycoprotein (E1-195-296) from a panel of 22 rubella viruses obtained from Europe, USA and Asia between 1963-1995. E1-195

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea0cbfc29bbf600ad81e02a628f09d6
https://doi.org/10.1099/0022-1317-77-10-2523

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Analytic sensitivities of hybrid-capture, consensus and type-specific polymerase chain reactions for the detection of human papillomavirus type 16 DNA

Autor: John Cason, Philip Rice, Saban Cavuslu, Chandrima Biswas, Jennifer M. Best, William G. Starkey, Barbara Kell, Jon M. Bible, Christine Mant

Publikováno v: Journal of Medical Virology. 49:319-324

Human papillomavirus type 16 (HPV-16) DNA is detected commonly in cervical carcinomas; in this study, we have determined the analytical sensitivities of Hybrid Capture, HPV-consensus PCR, and three HPV-16-specific polymerase chain reactions (PCRs) fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5af13b235cadb161d1eaa0a1b545a9
https://doi.org/10.1002/(sici)1096-9071(199608)49:4<319::aid-jmv10>3.0.co

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Detection of human papillomavirus type 16 in microtitre plate based immuno-enzymatic assays: use to determine E5 gene expression in cervical carcinomas

Autor: John Cason, Barbara Kell, William G. Starkey, Saban Cavuslu, Jennifer M. Best

Publikováno v: Clinical and Diagnostic Virology. 5:215-218

Background: E5-based nested polymerase chain reaction (PCR) assays and a PCR-enzyme immunoassay (EIA) to detect human papillomavirus type 16 (HPV-16) DNA have been developed. These assays were designed to detect small amounts of HPV-16 DNA for epidem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b9c7ab32aeb5530582bb204a9980c
https://doi.org/10.1016/0928-0197(96)00225-5

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Recombinant rubella E1 fusion proteins for antibody screening and diagnosis

Autor: Jennifer M. Best, Sabah Al-Mumin, Jane Newcombe, Angus I. Knight, Peter G. Sanders, William G. Starkey

Publikováno v: Clinical and Diagnostic Virology. 2:149-163

Background: Until rubella is eradicated there will be a continuing need for rubella antibody surveillance. Antigen production using recombinant DNA technology may be a viable alternative to traditional techniques of producing antigens for enzyme immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837cf04b828c824dab80d9537699f713
https://doi.org/10.1016/0928-0197(94)90019-1

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Cervical lesions are associated with human papillomavirus type 16 intratypic variants that have high transcriptional activity and increased usage of common mammalian codons

Autor: Jangu E. Banatvala, Paul T. Seed, Chandrima Biswas, Jon M. Bible, Peter Muir, Jennifer M. Best, William G. Starkey, Christine Mant, Barbara Kell, K. Shanti Raju, John Cason

Publikováno v: Europe PubMed Central

Human papillomavirus type 16 (HPV-16) is a major cause of cervical neoplasia, but only a minority of HPV-16 infections result in cancer. Whether particular HPV-16 variants are associated with cervical disease has not yet been clearly established. An

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3887557f67d2b85548d8e007e498cbb
https://pubmed.ncbi.nlm.nih.gov/10811935

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Molecular analysis of rubella virus epidemiology across three continents, North America, Europe, and Asia, 1961-1997

Autor: Shigetaka Katow, Scott C. Weaver, Jennifer M. Best, Trent J. Bosma, Teryl K. Frey, William G. Starkey, Emily S. Abernathy, Karen Corbett

Publikováno v: ResearcherID

E1 gene nucleotide sequences of 63 rubella virus isolates from North America, Europe, and Asia isolated between 1961 and 1997 were compared phylogenetically. Two genotypes were evident: Genotype I contained 60 viruses from North America, Europe, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821cc0eb87dfc0003b3e53912d122c5f
https://pubmed.ncbi.nlm.nih.gov/9728531

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A Replication-Competent Retrovirus Arising from a Split-Function Packaging Cell Line Was Generated by Recombination Events between the Vector, One of the Packaging Constructs, and Endogenous Retroviral Sequences

Autor: Richard G. Vile, William G. Starkey, Heung Chong

Previously we reported the presence of a replication-competent retrovirus in supernatant from a vector-producing line derived from a widely used split-function amphotropic packaging cell line. Rigorous routine screening of all retroviral stocks produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9413de78a8fc9c3351b12b80b437ca
https://europepmc.org/articles/PMC109708/

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Enterovirus infection of the central nervous system of humans: lack of association with chronic neurological disease

Autor: V. E. R. Anderson, Peter Muir, William G. Starkey, N. J. Cairns, G. T. Spencer, L. C. Archard, Jangu E. Banatvala, F. Nicholson, M. Khan, R. S. Howard, J. F. Ajetunmobi, P. N. Leigh

Publikováno v: The Journal of general virology. 77

We have searched, using a sensitive nested-PCR, for enterovirus RNA in cerebrospinal fluid and post mortem central nervous system (CNS) tissue from patients with previous poliomyelitis with or without late functional deterioration, patients with moto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3037c4a4f1c4a5f4b7427236203e3fad
https://pubmed.ncbi.nlm.nih.gov/8757988

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Human papillomavirus type 16 in infants: use of DNA sequence analyses to determine the source of infection

Autor: J. M. Best, Kankipati S. Raju, Chandrima Biswas, William G. Starkey, Barbara Kell, John Cason, Jeremy N. Kaye

Publikováno v: The Journal of general virology. 77

Perinatal transmission of human papillomavirus type 16 (HPV-16) and persistence of virus DNA in infants until 6 months of age has been described. To confirm the origin of infant infections as maternal, we determined the nucleotide sequence of the ups

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ed0f3b4cdd9a405ae8f88157764812
https://pubmed.ncbi.nlm.nih.gov/8683198

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