Zobrazeno 1 - 10
of 17
pro vyhledávání: '"William G. Dewhurst"'
Autor:
David J. McManus, Darrell D. Mousseau, Augusto V. Juorio, Glen B. Baker, Andrew J. Greenshaw, William G. Dewhurst
Publikováno v:
Cellular and Molecular Neurobiology. 13:3-13
1. The effects of age and of chronic antidepressant treatment on [3H]tryptamine and [3H]dihydroalprenolol binding site density were measured in brain cortical membranes from male Sprague-Dawley rats. 2. The density but not the affinity of [3H]tryptam
Publikováno v:
Journal of Pharmacological Methods. 25:147-155
p -Chloro- α -fluoromethylphenylethylamine(fluoro-p-chloroamphetamine)(FpCA) has been shown in acute studies to be a less potent depletor of the neurotransmitter amine 5-hydroxytryptamine (5-HT) in brain than is p -chloroamphetamine (pCA). Gas Chrom
Publikováno v:
Drug Development Research. 24:135-139
Levels of tryptophan (Trp), 5-hydroxytryptamine (5-HT), and 5-hydroxyindole-3-acetic acid (5-HIAA) in rat brain were measured at 1, 2, 4, and 24 hr after intraperitoneal administration of p-chloroamphetamine (pCA) (0.03 mmol/kg) or of p-cloro-α-fluo
Publikováno v:
Brain research bulletin. 25(1)
Time- and dose-response studies were conducted to determine the effects of the antidepressant and antipanic drug phenelzine (a monoamine oxidase inhibitor) on whole brain levels of the aliphatic amino acid alanine. At a dose of phenelzine of 15 mg/kg
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 6:495-498
1. Urinary excretion (24 h) of 2-phenylethylamine (PEA), m - and p -tyramine ( m - and p -TA), tryptamine (T), 5-hydroxytryptamine (5-HT), 3-methoxytyramine (3-MTA), normetanephrine (NME), 3-methoxy-4-hydroxyphenylethylene glycol (MHPG), kynurenine (
Publikováno v:
Biochemical Pharmacology. 30:861-867
A gas chromatography method, using electron capture detection, is described for measurement of the monoamine oxidase inhibitor tranylcypromine (TCP) in rat brain regions. The analytical method involves extraction of the drug from tissue homogenate wi
Autor:
Glen B. Baker, William G. Dewhurst, Donald F. LeGatt, G. Hopkinson, Ronald T. Coutts, G.J. McIntosh
Publikováno v:
Progress in Neuro-Psychopharmacology. 5:565-568
1. 1. An electron-capture gas chromatographic procedure for the simultaneous quantitation of urinary levels of amines of psychiatric interest has been developed. 2. 2. The amines were isolated from urine using a liquid ion exchanger, then acetylated
Autor:
William G. Dewhurst, Judith M. Baker
Publisher Summary This chapter discusses the fluorescence techniques for detection and quantitation of amines. It is well known that organic molecules absorb light energy, which results in various interatomic bonds being raised to a higher energy lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32127305718564cce435a137980fddc
https://doi.org/10.1016/s0167-9244(08)70285-3
https://doi.org/10.1016/s0167-9244(08)70285-3