Zobrazeno 1 - 9
of 9
pro vyhledávání: '"William G. Chapman"'
Publikováno v:
Journal of Nervous & Mental Disease. 201:1035-1039
This study sought to identify factors contributing to symptoms of depression and posttraumatic stress disorder (PTSD) in recently deployed combat veterans. A sample of 168 active duty military personnel completed measures of combat exposure, deployme
Autor:
Zengqi Lu, Lauren R. Samuels, Katherine A. Gifford, Dandan Liu, Stephen M. Damon, William G. Chapman Iv, Raymond R. Romano, Angela L. Jefferson
A cognitive concern from the patient, informant, or clinician is required for the diagnosis of mild cognitive impairment (MCI); however, the cognitive and neuroanatomical correlates of complaint are poorly understood.We assessed how self-complaint re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5fb3d492145dc58438a3d70c384fb6
https://europepmc.org/articles/PMC4351870/
https://europepmc.org/articles/PMC4351870/
Publikováno v:
Cancer Letters. 164:113-118
Induced transcription of a battery of stress response genes in mammals, including several phase I and phase II drug-metabolizing enzymes, is regulated by the electrophile responsive element (EpRE). Because previous directed mutagenesis of nucleotide
Autor:
Eric Raymond, Alex V. Trevino, Alexandra Vaisman, Stephen G. Chaney, Sandrine Faivre, Paul E. Juniewicz, Maryanne C. Herzig, William G. Chapman, Jan M. Woynarowski, Brenda Arnett, Maria Varchenko
Publikováno v:
Molecular Pharmacology. 58:920-927
Damage to cellular DNA is believed to determine the antiproliferative properties of platinum (Pt) drugs. This study characterized DNA damage by oxaliplatin, a diaminocyclohexane Pt drug with clinical antitumor activity. Compared with cisplatin, oxali
Publikováno v:
Biochimica et biophysica acta. 1444(2)
Bizelesin is a bifunctional AT-specific DNA alkylating drug. Our study characterized the ability of bizelesin to induce interstrand crosslinks, a potential lethal lesion. In genomic DNA of BSC-1 cells, bizelesin formed from approx. 0.3 to 6.03±0.85
Publikováno v:
Molecular pharmacology. 54(5)
Oxaliplatin is a clinical anticancer drug with a pharmacological profile distinct from that of cisplatin. Our studies compared site- and region-specificity of lesions induced by oxaliplatin and cisplatin in naked and intracellular DNA, respectively.
Autor:
Jan M. Woynarowski, Cheryl Napier, John R. MacDonald, William G. Chapman, Shih-Fong Chen, Steven K. Koester, Dean A. Troyer
Publikováno v:
Biochemical pharmacology. 54(11)
6-Hydroxymethylacylfulvene (HMAF, MGI 114) is a new alkylating antitumor sesquiterpenoid with promising and often curative antitumor activity in vivo. This study examined the ability of the drug to damage cellular DNA, induce apoptosis, and affect th
Autor:
Edward H. Kass, James Taylor, Charles H. Hennekens, Nancy R. Cook, William G. Chapman, Larry W. Laughlin, Paul A. Scherr, Bernard Rosner, Dennis A. Evans
Publikováno v:
American Journal of Epidemiology. 121:530-540
Measurements of blood pressure were obtained on 2,673 women from East Boston, Massachusetts, an urban, working class neighborhood, in surveys conducted in both 1973 and 1976-1977. Of these, 927 women participated in a third survey in 1978. The women
Autor:
Jingoro Shimada, Lillian Miao, Bernard Rosner, Charles H. Hennekens, David N. Williams, John W. Warren, Larry W. Laughlin, Denis A. Evans, James O. Taylor, William G. Chapman
Publikováno v:
The Journal of infectious diseases. 138(6)
A survey for bacteriuria was conducted in a community-wide, unselected population of women 16--69 years old. The overall prevalence of bacteriuria was 3.5%. The prevalence of bacteriuria increased with age with a linear trend, but with a significant