Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William G, Romanow"'
Autor:
Derek E. Piper, William G. Romanow, Ruwanthi N. Gunawardane, Preston Fordstrom, Stephanie Masterman, Oscar Pan, Stephen T. Thibault, Richard Zhang, David Meininger, Margrit Schwarz, Zhulun Wang, Chadwick King, Mingyue Zhou, NigelP.C. Walker
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1711-1719 (2015)
LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. Patients with loss-of-function
Externí odkaz:
https://doaj.org/article/b3706d7d8e0b442f9e08dfa98b04c870
Autor:
Xiaoshan Min, Sheree Johnstone, Wei Wang, Zhulun Wang, Xinchao Yu, Jennifer Weiszmann, William G. Romanow, Stephen T. Thibault, Yang Li
Publikováno v:
Journal of Biological Chemistry. 293:14678-14688
Fibroblast growth factor 21 (FGF21), an endocrine hormone in the FGF family, plays a critical role in regulating metabolic homeostasis and has emerged as a therapeutic target for metabolic diseases, including Type 2 diabetes mellitus. FGF21 functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7cbe79247186146cd43320c77ebf00
https://doi.org/10.1074/jbc.ra118.004343
https://doi.org/10.1074/jbc.ra118.004343
Autor:
William G. Romanow, Stephen T. Thibault, Preston Fordstrom, Derek E. Piper, Nigel Walker, Mingyue Zhou
Publikováno v:
Protein Expression and Purification. 125:1-6
Lecithin-cholesterol acyltransferase (LCAT) is a key enzyme in the esterification of cholesterol and its subsequent incorporation into the core of high density lipoprotein (HDL) particles. It is also involved in reverse cholesterol transport (RCT), t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b6a87736688c7f556297437c605466
https://doi.org/10.1016/j.pep.2015.09.003
https://doi.org/10.1016/j.pep.2015.09.003
Autor:
Cheryl Isaac, Murphy, Helen, Piwnica-Worms, Stefan, Grünwald, William G, Romanow, Nicole, Francis, Hua-Ying, Fan, Sharon, Marr
Publikováno v:
Current protocols in molecular biology. 123(1)
This article describes how to analyze protein expression in cells infected with recombinant baculovirus on a small scale for optimizing protein production, how to maximize and scale up recombinant protein production, and how to purify recombinant pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09e18dd047716c226c6d8bdb55aa970b
https://pubmed.ncbi.nlm.nih.gov/29953734
https://pubmed.ncbi.nlm.nih.gov/29953734
Autor:
Zhulun Wang, David Park Meininger, Oscar Pan, Ruwanthi N. Gunawardane, Chadwick T. King, Richard Zhang, Mingyue Zhou, Stephen T. Thibault, Derek E. Piper, William G. Romanow, Nigel Walker, Preston Fordstrom, Margrit Schwarz, Stephanie Masterman
Publikováno v:
Journal of Lipid Research. 56:1711-1719
LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. Patients with loss-of-function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9270c529852996fdd4715ab74b29483
https://doi.org/10.1194/jlr.m059873
https://doi.org/10.1194/jlr.m059873
Autor:
Nicole J. Francis, Stefan Grünwald, Hua Ying Fan, Sharon K. Marr, William G. Romanow, Helen Piwnica-Worms, Cheryl Isaac Murphy
Publikováno v:
Current Protocols in Molecular Biology. 123:e61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67fd6bb5b37b243bf5c4fa367867767b
https://doi.org/10.1002/cpmb.61
https://doi.org/10.1002/cpmb.61
Autor:
Bei Shan, Simon Jackson, Qiang Liu, William G. Romanow, Derek E. Piper, Nigel Walker, Stephen T. Thibault, Susan Shetterly
Publikováno v:
Structure. 15(5):545-552
SummaryProprotein convertase subtilisin kexin type 9 (PCSK9) has been shown to be involved in the regulation of extracellular levels of the low-density lipoprotien receptor (LDLR). Although PCSK9 is a subtilase, it has not been shown to degrade the L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72659780d8857c7e3556d36c59b50801
Autor:
Steven D. Clouse, E. Zamski, Jenneth M. Sasse, Man-Ho Oh, Rachel C. Smith, William G. Romanow
Publikováno v:
Plant and Cell Physiology. 39:124-130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab89f053b56c86717c673ce0287449c6
https://doi.org/10.1093/oxfordjournals.pcp.a029283
https://doi.org/10.1093/oxfordjournals.pcp.a029283
Autor:
Higbee Jared Martin, Bei Shan, Margrit Schwarz, Wen-Chen Yeh, William G. Romanow, Qiong Cao, Mei Lu, Joyce Chi Yee Chan, Richard Zhang, Yongmei Di, Ping Cao, Maurice Emery, Evelyn Yang, Stephen T. Thibault, Lei Zhou, Susan Shetterly, Gayle Kwon, Timothy W. Yu, Dongming Liu, Wenyan D. Shen, Kirk Henne, Oscar Pan, Mei-Mei Tsai, Heather Salomonis, Bryna Fuchslocher, Ziva Arimura, Nigel Walker, Qiang Liu, Mark Daris, Derek E. Piper, Kijeong Lee, Simon Mark Jackson, Wei Wang, Chadwick T. King, Jie Tang, Xiao-Ping Yang, Jackie Sheng, Yan Wang, Marc W. Retter, Zhen Xia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(24)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates serum LDL cholesterol (LDL-C) by interacting with the LDL receptor (LDLR) and is an attractive therapeutic target for LDL-C lowering. We have generated a neutralizing anti-PCSK9 antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6547ec9849672f16af5dab324c2e1c67
https://pubmed.ncbi.nlm.nih.gov/20425252
https://pubmed.ncbi.nlm.nih.gov/20425252
Autor:
Hua Ying Fan, Nicole J. Francis, Cheryl Isaac Murphy, William G. Romanow, Helen Piwnica-Worms, Stefan Grünwald
Publikováno v:
Current Protocols in Molecular Biology
This unit describes the maintenance and care of insect cell cultures as well as the generation, purification, and storage of recombinant baculoviruses. Procedures are included for maintenance and subculturing of insect cells and cotransfection of ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880d8e411bbb6769da721061ed408cd7
https://pubmed.ncbi.nlm.nih.gov/18265340
https://pubmed.ncbi.nlm.nih.gov/18265340