Výsledky vyhledávání - "William Feser"

Data from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

Autor: Wilbur A. Franklin, Paul A. Bunn, Lynn Heasley, Fred R. Hirsch, Sarah Braudrick, Patrick J. Blatchford, Timothy C. Kennedy, William Feser, Anna E. Baron, Robert L. Keith, York E. Miller, Dexiang Gao, Daniel T. Merrick

Bronchial dysplasia (BD), a presumed precursor of pulmonary squamous cell carcinoma (SCC), rarely progresses to invasive cancer. A high-risk cohort at the University of Colorado provided an opportunity to directly sample airway epithelium at mapped s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cadf6a6c2191f754f7570d49d73e770
https://doi.org/10.1158/1940-6207.c.6546989.v1

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Figure S2 from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

Supplemental figure S2. Univariable analysis comparing frequency of SCC in cases grouped by highest baseline (BL) histology score (HS) or mean baseline histology score using a cutoff of HS > 5 (moderate dysplasia).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dc3451d62d9fe21faf8a5756f42799
https://doi.org/10.1158/1940-6207.22533218

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Supplemental tables and figure legends from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

SUPPLEMENTAL TABLE S1. BIOPSY AND CLINCAL CHARACTERISTICS. SUPPLEMENTAL TABLE S2. BASELINE HISTOLOGY AND OUTCOME.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33cb7fd264208adc5fad6107bd399ad3
https://doi.org/10.1158/1940-6207.22533212

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Figure S1 from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

Supplemental figure S1. Univariable analysis comparing frequency of SCC using four different definitions of persistent bronchial dysplasia (PBD; RBD = regressive BD) for sites with any baseline diagnosis (HS 1-7).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68287807a4b6b9bd08b10e520be1fac5
https://doi.org/10.1158/1940-6207.22533221

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Figure S3 from Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

Supplemental figure S3. Sites that show HGD in follow-up biopsies are more frequent in subjects that have prevalent (Prev) or develop incident (Inc) squamous cell carcinoma (SCC) as compared to those without cancer (No CA). *p < 0.05.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320918758e47710ad76db8b43a6f2485
https://doi.org/10.1158/1940-6207.22533215

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Integrated Biomarker for the Management of Indeterminate Pulmonary Nodules

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0e22f1c1e0d690c3f89440409e909aa
https://doi.org/10.2139/ssrn.3684471

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Abstract PR04: Distinctive squamous cell carcinoma protein signatures

Autor: Anna E. Barón, Jill M. Siegfried, Stephen A. Williams, York Miller, Wilbur Franklin, Edward Brody, Thomas Muley, Rachel M. Ostroff, Harvey Pass, Michael R. Mehan, William Rom, Adrie van Bokhoven, William Feser, Holly Wolf, Daniel T. Merrick

Publikováno v: Clinical Cancer Research. 20:PR04-PR04

Squamous cell carcinoma (SQ) of the lung causes approximately 400,000 deaths per year worldwide, and no specifically targeted treatments yet exist. We used the SOMAscan proteomic platform (which measures 1129 proteins with a median limit of detection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1dc8b9ffc258cd42b586e49a19f0d12f
https://doi.org/10.1158/1078-0432.14aacriaslc-pr04

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Defining a FISH chromosomal aneusomy panel for predicting lung cancer in the setting of CT-detected lung nodules

Autor: William Feser, Anna E. Barón, Holly J. Wolf, Daniel T. Merrick, Wilbur A. Franklin, Marileila Varella-Garcia, Marina T. Lewis, York E. Miller, Margaret Skokan

Publikováno v: Journal of Clinical Oncology. 30:10580-10580

10580 Background: Early detection of lung cancer by CT is supported by the National Lung Screening Trial; but while sensitivity of CT is high, specificity is low. Biomarkers to predict the malignant nature of CT detected lung nodules would have great

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::508912a40fe0d3409bce0f99dbdf8ad0
https://doi.org/10.1200/jco.2012.30.15_suppl.10580

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