Zobrazeno 1 - 10
of 27
pro vyhledávání: '"William F. Pralong"'
Publikováno v:
Experimental Neurology. 193:53-64
Adenosine is an important inhibitory modulator of brain activity. In a previous ex vivo gene therapy approach, local release of adenosine by encapsulated fibroblasts implanted into the vicinity of an epileptic focus, was sufficient to provide transie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5003103572bbf197dd0ae6cee029f1
https://doi.org/10.1016/j.expneurol.2004.12.012
https://doi.org/10.1016/j.expneurol.2004.12.012
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 2, Pp 283-289 (2004)
Viral delivery of glial cell line-derived neurotrophic factor (GDNF) currently represents one of the most promising neuroprotective strategies for Parkinson's Disease (PD). However, the effect of this neurotrophic factor has never been tested in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8219851ef18fa79aa688ba2d33cd4028
https://doi.org/10.1016/j.nbd.2004.06.008
https://doi.org/10.1016/j.nbd.2004.06.008
Autor:
Aldonza Ania-Lahuerta, Isabelle Borghini, William F. Pralong, Claes B. Wollheim, Asllan Gjinovci, Giovanna Ferrari, Romano Regazzi
Publikováno v:
Journal of Neurochemistry. 62:686-696
Defective protein kinase C (PKC) has been implicated in impaired Na+,K(+)-ATPase activity in the sciatic nerve of streptozotocin-induced diabetic rats. In the present study, alpha, beta I, beta II, gamma, delta, and epsilon isoform-specific antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c9a5d885cae659fdd901ce5a1a78a31
https://doi.org/10.1046/j.1471-4159.1994.62020686.x
https://doi.org/10.1046/j.1471-4159.1994.62020686.x
Autor:
E. Andersen, Denis F. Hochstrasser, William F. Pralong, Marc R. Wilkins, T. Kojima, G. Cimasoni, Jean-Charles Sanchez
Publikováno v:
Journal of Dental Research. 79:740-747
Human gingival crevicular fluid contains unidentified proteins which might play a role as markers in periodontal diseases. Therefore, low-molecular-weight proteins found in human gingival crevicular fluid (GCF), but absent from serum, were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff30b100148d5f4435304e7fb9ed208
https://doi.org/10.1177/00220345000790020701
https://doi.org/10.1177/00220345000790020701
Autor:
Asllan Gjinovci, William F. Pralong, Robin E. Offord, Lan Vu, Alistair D. Kippen, Keith Rose, Fabrice Cerini, Reto Stöcklin
Publikováno v:
Analytical Biochemistry. 262:17-22
We describe a novel bioassay to measure specific insulin-like activity in primary cultures of rat hepatocytes by determination of [3H]glycogen from d-[6-3H]glucose. The dose-response curve of insulin in this assay exhibited an EC50 of 0.42 (+/-0.04)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbd0d9ac4f3763a4738099744aa5da6
https://doi.org/10.1006/abio.1998.2731
https://doi.org/10.1006/abio.1998.2731
Autor:
Rosella Fulceri, Alessandra Gamberucci, Angelo Benedetti, William F. Pralong, Paola Marcolongo
Publikováno v:
Scopus-Elsevier
Histone H2A (1–10 µg/ml) added to Ehrlich ascite cell suspensions promoted: (i) Ca2+ influx, but no apparent intracellular Ca2+ mobilization; (ii) plasma-membrane depolarization and Na+ influx in Ca2+-free medium, which were recovered by Ca2+ read
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cb80cab7a6f52975b3fb4cf439b5e0
https://doi.org/10.1042/bj3310623
https://doi.org/10.1042/bj3310623
Publikováno v:
Cell Calcium, Vol. 19, No 6 (1996) pp. 535-46
The mechanism underlying the generation of cytosolic free Ca2+ ([Ca2+]i) oscillations by bombesin, a receptor agonist activating phospholipase C, in insulin secreting HIT-T15 cells was investigated. At 25 microM, 61% of cells displayed [Ca2+]i oscill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4022bdc85aa0e7566044d9c4efdf5b
https://doi.org/10.1016/s0143-4160(96)90063-9
https://doi.org/10.1016/s0143-4160(96)90063-9
Publikováno v:
Endocrinology. 137:1841-1850
Signal transduction of two mitogens for pancreatic beta-cells, GH and PRL, was investigated using the differentiated insulin-secreting cell line, INS-1. Addition of human GH (hGH) or ovine PRL in a serum-substitute medium increased growth, insulin co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::976ec40754c9cdf138877a422b6953de
https://doi.org/10.1210/endo.137.5.8612523
https://doi.org/10.1210/endo.137.5.8612523
Publikováno v:
Journal of Biological Chemistry. 269:27310-27314
During cell activation, Ca2+, by stimulating the NADH-producing mitochondrial dehydrogenases, triggers the generation of reducing equivalents whereby ATP production is sustained. In cell populations, [Ca2+] changes in the mitochondrial matrix were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1863742d8e506f089ff78fcb22148b51
https://doi.org/10.1016/s0021-9258(18)46986-4
https://doi.org/10.1016/s0021-9258(18)46986-4
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1175:107-113
(1) A new insulin-secreting cell line (INS-1; Asfari et al. (1992) Endocrinology 130, 167–178) has been used to study the regulation by Ca2+ of mitochondrial FAD-linked glycerol-phosphate dehydrogenase (FAD-GPDH) in situ. (2) Enzyme activity was ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3296e09e6f5f824818360b44e481e726
https://doi.org/10.1016/0167-4889(92)90016-5
https://doi.org/10.1016/0167-4889(92)90016-5