Zobrazeno 1 - 10
of 61
pro vyhledávání: '"William F. Maragos"'
Autor:
Shaji Theodore, Wayne A. Cass, Avindra Nath, Joseph Steiner, Kristie Young, William F. Maragos
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 663-668 (2006)
Our previous studies demonstrated that the psychostimulant methamphetamine (MA) and the human immunodeficiency virus-1 (HIV-1) protein Tat interacted to cause enhanced dopaminergic neurotoxicity. The present study examined whether tumor necrosis fact
Externí odkaz:
https://doaj.org/article/677a5b270a3c4fdb97356222aea90769
Autor:
William F. Maragos, Amit S. Korde
Publikováno v:
Mitochondrion. 59:76-82
Our laboratory has demonstrated that functional N-methyl- d -aspartate-like receptors are present on neuronal mitochondria (NMDAm). This novel site gates the influx of Ca2+ and causes a several-fold increase in ATP levels. Although elevations in ATP
Autor:
Pamela E. Knapp, A. Rory McQuiston, Jason J. Paris, Kurt F. Hauser, Christina J. Schier, Aaron J. Barbour, William F. Maragos, Virginia D. McLane, William D. Marks
Publikováno v:
The Journal of Neuroscience. 37:5758-5769
Despite marked regional differences in HIV susceptibility within the CNS, there has been surprisingly little exploration into the differential vulnerability among neuron types and the circuits they underlie. The dorsal striatum is especially suscepti
Autor:
Amit S Korde, William F Maragos
Publikováno v:
Annals of Neurosciences. 16:49-53
Autor:
William F. Maragos, Pamela E. Knapp, David J. Volsky, Nazira El-Hage, Kurt F. Hauser, Avindra Nath, Anne Stiene-Martin, Yuri Persidsky
Publikováno v:
Journal of Neurochemistry. 100:567-586
Neuronal dysfunction and degeneration are ultimately responsible for the neurocognitive impairment and dementia manifest in neuroAIDS. Despite overt neuronal pathology, HIV-1 does not directly infect neurons; rather, neuronal dysfunction or death is
Autor:
Justin C. McArthur, R. Gilberto Gonzalez, Eliezer Masliah, William F. Maragos, Christopher Power, Joan W. Berman, Walter Royal, Avindra Nath, Diane B. Miller, Wen-Zhe Ho, Thomas J. Rogers, Glen R. Hanson, Brian M. Cox, Linda Chang, James P. O'Callaghan, Howard S. Fox, Kurt F. Hauser, Yuri Persidsky, Jau-Shyong Hong, Eugene O. Major, Monica J. Carson
Publikováno v:
Journal of Neuroimmune Pharmacology. 1:351-399
Neurological complications of human immunodeficiency virus (HIV) infection are a public health problem despite the availability of active antiretroviral therapies. The neuropathogenesis of HIV infection revolves around a complex cascade of events tha
Autor:
Avindra Nath, Kristie L. Young, William F. Maragos, Wayne A. Cass, Joseph P. Steiner, Shaji Theodore
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 3, Pp 663-668 (2006)
Our previous studies demonstrated that the psychostimulant methamphetamine (MA) and the human immunodeficiency virus-1 (HIV-1) protein Tat interacted to cause enhanced dopaminergic neurotoxicity. The present study examined whether tumor necrosis fact
Publikováno v:
Annals of the New York Academy of Sciences. 1074:178-190
The human immunodeficiency virus-1 (HIV-1) affects the central nervous system (CNS) in approximately 30% of infected individuals and basal ganglia structures seem to be most affected. The HIV-1-transactivating protein, Tat, has been suggested to be p
Publikováno v:
Neuroscience. 137:925-935
Dysfunction of the dopaminergic system accompanied by loss of dopamine in the striatum is a major feature of human immunodeficiency virus-1-associated dementia. Previous studies have shown that human immunodeficiency virus-1-associated dementia patie
Autor:
William M. Pierce, D. Allan Butterfield, Marzia Perluigi, H. Fai Poon, William F. Maragos, Jon B. Klein, Vittoriio Calabrese, Chiara Cini, Carlo De Marco
Publikováno v:
Molecular & Cellular Proteomics. 4:1849-1861
Huntington disease (HD) is a hereditary neurodegenerative disorder characterized by motor, psychiatric, and cognitive symptoms. The genetic defect responsible for the onset of the disease, expansion of CAG repeats in exon 1 of the gene that codes for