Zobrazeno 1 - 10
of 34
pro vyhledávání: '"William F. Herblin"'
Publikováno v:
Life Sciences. 63:223-234
A novel binding site for angiotensin II has been identified in certain murine tissues. This site, denoted ATm, is distinct from both the AT1 and AT2 sites, as well as the various atypical sites that have been described. The site has a low affinity fo
Autor:
Ulla Crickard, Janet L. Gross, Kristi Eidsvoog, Kent Crickard, William F. Herblin, Shashikant Lele, Mahmood Yoonessi
Publikováno v:
Gynecologic Oncology. 55:277-284
Basic fibroblast growth factor (bFGF) and other members of the FGF family share several biological properties that have the potential to mediate neoplastic cell growth. To test the hypothesis that bFGF may play a role in human ovarian cancer cell gro
Publikováno v:
Expert Opinion on Therapeutic Patents. 4:641-654
(1994). Overview Oncologic, Endocrine & Metabolic: Recent advances in angiogenesis inhibitors. Expert Opinion on Therapeutic Patents: Vol. 4, No. 6, pp. 641-654.
Autor:
William F. Herblin, Janet L. Gross
Publikováno v:
Molecular and chemical neuropathology. 21:329-336
Angiogenesis is a complex sequence of events leading to the formation of new capillaries. Although essential to maturation and wound healing, most angiogenesis in the adult is associated with pathological events, such as the development of solid tumo
Autor:
A. Yayon, Kristi Eidsvoog, P. Czerniak, Janet L. Gross, Daniel L. Dexter, B. A. Dusak, M. D. Diamond, T. Sun, William F. Herblin
Publikováno v:
JNCI: Journal of the National Cancer Institute. 85:121-131
Background Recombinant human basic fibroblast growth factor (rHu-bFGF) is known to stimulate proliferation in some tumor cells and to modulate tumor vascularization. Purpose The purpose of this study was to examine the possible role of this agent in
Publikováno v:
Cancer. 70:2673-2680
A prominent feature of some tumors of the central nervous system is angiogenesis. In this process, basic fibroblastic growth factor (bFGF) plays a key role. Surgical specimens of 23 human brain tumors were examined, by immunocytochemistry with a high
Autor:
John V. Duncia, Pancras C. Wong, David D. Christ, Pieter B.M.W.M. Timmermans, T. Bradford Barnes, Andrew T. Chiu, William F. Herblin
Publikováno v:
Cardiovascular Drug Reviews. 9:317-339
Autor:
William F. Herblin, Andrew T. Chiu, Dale E. McCall, Robert J. Ardecky, David J. Carini, John V. Duncia, Lori J. Pease, Pancras C. Wong, Ruth R. Wexler, Alexander L Johnson, Pieter B.M.W.M. Timmermans
Publikováno v:
American Journal of Hypertension. 4:299S-302S
The possibility of receptor heterogeneity in the angiotensin II (AII) system has been suggested previously, based on differences in Kd values or sensitivity to thiol reagents. One of the authors earliest indications was the frequent observation of in
Publikováno v:
Arthritis & Rheumatism. 34:314-324
The interactions of interleukin-1 beta (IL-1 beta) and basic fibroblast growth factor (bFGF) with monolayer cultures of rabbit articular chondrocytes were examined. Both agonists resulted in a synergistic increase in prostanoid production, to levels
Publikováno v:
Trends in Pharmacological Sciences. 12:55-62
Substantial progress has been made recently in the development of nonpeptide angiotensin II receptor antagonists, a goal that has long remained an unmet challenge. Pieter Timmermans and colleagues review the pharmacology and the course of events that