Zobrazeno 1 - 10
of 15
pro vyhledávání: '"William F. Goure"'
Autor:
Franz Hefti, Patricia Ann Walicke, Jasna Jerecic, Grant A. Krafft, Kent S. Iverson, William F. Goure
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
William F. Goure, Patricia Ann Walicke, Grant A. Krafft, Jasna Jerecic, Kent S. Iverson, Franz Hefti
Publikováno v:
Trends in pharmacological sciences. 34(5)
Soluble Aβ oligomers are now widely recognized as key pathogenic structures in Alzheimer's disease. They inhibit synaptic function, leading to early memory deficits and synaptic degeneration, and they trigger the downstream neuronal signaling respon
Autor:
William F. Goure
Publikováno v:
Journal of Heterocyclic Chemistry. 30:71-80
The facile two step, one pot synthesis of heretofore unknown 2-hydroxy-4,6-bis(trifluoromethyl)-pyridine-5-carboxylates by condensation of 3-amino-4,4,4-trifluoro-2-butenoate with 4,4,4-trifluoroacetoacetyl chloride and subsequent intramolecular cycl
Autor:
William F. Goure
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 24
Publikováno v:
Journal of Agricultural and Food Chemistry. 39:981-986
The synthesis and SAR of herbicidal N-substituted 2,6-bis(polyfluoromethyl)-1,2-dihydropyridine-3, 5-dicarboxylates are described. N-substituted dihydropyridines were readily prepared by treatment of the corresponding dihydropyridyl anions with elect
Autor:
William F. Goure
Publikováno v:
The GMO Handbook ISBN: 9781617374821
The aim of this chapter is not to review the many different transgenic crop products in development in academic and industrial laboratories throughout the world. These are adequately described in published reviews and literature articles and on Inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b347ea704dc02c6d517871214731134
https://doi.org/10.1007/978-1-59259-801-4_10
https://doi.org/10.1007/978-1-59259-801-4_10
Publikováno v:
Alzheimer's Research & Therapy
Levels of amyloid-beta monomer and deposited amyloid-beta in the Alzheimer’s disease brain are orders of magnitude greater than soluble amyloid-beta oligomer levels. Monomeric amyloid-beta has no known direct toxicity. Insoluble fibrillar amyloid-b
Publikováno v:
Synthesis and Chemistry of Agrochemicals III ISBN: 9780841224735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0807b8dcd85b9618b0a17a8fa6255c89
https://doi.org/10.1021/bk-1992-0504.ch016
https://doi.org/10.1021/bk-1992-0504.ch016