Zobrazeno 1 - 3
of 3
pro vyhledávání: '"William F. Dall' Acqua"'
Autor:
Jincheng Wu, Partha S. Chowdhury, Andrew C. Mercer, Xiaodong Xiao, Herren Wu, Andrey Tovchigrechko, Michael R. Kierny, William F. Dall’ Acqua, Saravanan Rajan
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-8 (2018)
The human antibody repertoire is increasingly being recognized as a valuable source of therapeutic grade antibodies. However, methods for mining primary antibody-expressing B cells are limited in their ability to rapidly isolate rare and antigen-spec
Autor:
Nita K. Patel, Susan R. Palaszynski, Solomon Langermann, William F. Dall’ Acqua, E. Sally Ward, Robert M. Woods, Yambasu A. Brewah, Peter A. Kiener, Herren Wu
Publikováno v:
The Journal of Immunology. 169:5171-5180
Many biological functions, including control of the homeostasis and maternofetal transfer of serum γ-globulins, are mediated by the MHC class I-related neonatal FcR (FcRn). A correlation exists in mice between the binding affinity of IgG1/Fc fragmen
Autor:
Jiaqi Huang, Herren Wu, Bahija Jallal, Michael Oberst, Maria Amann, William F. Dall’ Acqua, Melissa Damschroder, Pamela Trail, Li Peng, Steven Coats, Kristen Lekstrom, Yihong Yao, Patrick A. Baeuerle, Philip Brohawn, Scott A. Hammond
Publikováno v:
Cancer Research. 70:2584-2584
MEDI-565 (MT111) is a novel bispecific single-chain antibody of the BiTE (Bi-specific T-cell engager) class that transiently links carcinoembryonic antigen (CEA) on tumor cells with human CD3 on T cells. Engagement of CD3 and CEA by MEDI-565 induces