Zobrazeno 1 - 10
of 105
pro vyhledávání: '"William F Hoffman"'
Autor:
Jennifer M Loftis, Michael Lasarev, Xiao Shi, Jodi Lapidus, Aaron Janowsky, William F Hoffman, Marilyn Huckans
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0220270 (2019)
BackgroundMethamphetamine (MA) is a potent agonist at the trace amine-associated receptor 1 (TAAR1). This study evaluated a common variant (CV) in the human TAAR1 gene, synonymous single nucleotide polymorphism (SNP) V288V, to determine the involveme
Externí odkaz:
https://doaj.org/article/cc5448f2e84b47b78eb752cafb282caf
Autor:
William F. Hoffman, Merel B. Jacobs, Laura E. Dennis, Holly D. McCready, Alex W. Hickok, Sheehan B. Smith, Milky Kohno
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Methamphetamine use and psychopathy are associated with criminal behavior; however, it is unclear how methamphetamine use and psychopathy interact to promote violent, economic and drug offenses. Abnormalities in corticostriatal functional connectivit
Externí odkaz:
https://doaj.org/article/de50828935184c0e9b5294b4b42941d5
Autor:
Milky Kohno, Angelica M. Morales, Laura E. Dennis, Holly McCready, William F. Hoffman, P. Todd Korthuis
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
Naltrexone attenuates craving, and the subjective effects of methamphetamine and extended-release naltrexone (XR-NTX) reduces functional connectivity between regions of the striatum and limbic cortex. Naltrexone modulates neural activity at dopaminer
Externí odkaz:
https://doaj.org/article/d84f282fa60549439331e6c528f7083e
Publikováno v:
Frontiers in Psychiatry, Vol 8 (2017)
Alterations within mesocorticolimbic terminal regions commonly occur with alcohol use disorder (AUD). As pathological drug-seeking behavior may arise as a consequence of alcohol-induced neuroadaptations, it is critical to understand how such changes
Externí odkaz:
https://doaj.org/article/5a635c346150445cac342353a36da7d3
Publikováno v:
Molecular Psychiatry. 27:220-229
Dopamine system deficiencies and associated behavioral phenotypes may be a critical barrier to success in treating stimulant use disorders. Similarities in dopamine dysfunction between cocaine and methamphetamine use disorder but also key differences
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2022)
Frontiers in Psychiatry
Frontiers in Psychiatry
The increasing prevalence of illicit stimulant use among those in opioid treatment programs poses a significant risk to public health, stimulant users have the lowest rate of retention and poorest outcomes among those in addiction treatment, and curr
Autor:
Jennifer M. Loftis, Marilyn Huckans, Bethany Winters, Stephen J. Boyd, William F. Hoffman, Nathan Hantke, Grant Moncrief, Emily Sano, Laura E. Dennis, Kate Shirley, Milky Kohno, Holly McCready
Publikováno v:
J Clin Exp Neuropsychol
OBJECTIVE: To evaluate whether cognitive performance in adults with active methamphetamine use (MA-ACT) differs from cognitive performance in adults in remission from MA use disorder (MA-REM) and adults without a history of substance use disorder (CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec1a760111121c0d9910f621991cb79
https://europepmc.org/articles/PMC8979254/
https://europepmc.org/articles/PMC8979254/
Publikováno v:
Molecular psychiatry. 27(1)
Dopamine system deficiencies and associated behavioral phenotypes may be a critical barrier to success in treating stimulant use disorders. Similarities in dopamine dysfunction between cocaine and methamphetamine use disorder but also key differences
Autor:
William F. Hoffman, Jennifer M. Loftis, Hannah S. Luber, Renee Anderson, Michael Chang, Suzanne H. Mitchell, Laura E. Dennis, Marilyn Huckans, Milky Kohno, Michael Kolessar, Anna Sasaki, Daniel Kriz, Arthur A. Vandenbark, Holly McCready, Kenneth D. Flora
Publikováno v:
Journal of NeuroVirology. 24:738-751
BACKGROUND: Hepatitis C virus infected (HCV+) adults evidence increased rates of psychiatric and cognitive difficulties. This is the first study to use functional magnetic resonance imaging (fMRI) to examine brain activation in untreated HCV+ adults.
Autor:
William F. Hoffman, Milky Kohno, Jennifer M. Loftis, Laura E. Dennis, Marilyn Huckans, Holly McCready
Publikováno v:
Neuroscience Letters. 677:49-54
Methamphetamine (MA) causes an increase in pro-inflammatory cytokines in animal models and in humans. Resulting activation of microglia and neuro-inflammation could, via effects on reward networks, mediate behavioral characteristics of addiction. We