Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William Edgar Carson"'
Autor:
Giovanna Merchand-Reyes, Mikayla F. Bull, Ramasamy Santhanam, Maria L. Valencia-Pena, Rakesh A. Murugesan, Aadesh Chordia, Xiaokui-Molly Mo, Frank H. Robledo-Avila, Juan De Dios Ruiz-Rosado, William Edgar Carson, John C. Byrd, Jennifer A. Woyach, Susheela Tridandapani, Jonathan P. Butchar
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionTherapeutic antibodies have become a major strategy to treat oncologic diseases. For chronic lymphocytic leukemia, antibodies against CD20 are used to target and elicit cytotoxic responses against malignant B cells. However, efficacy is o
Externí odkaz:
https://doaj.org/article/2840c3664e3b44e69f5cbcfe156bc02d
Autor:
Aman Chauhan, Susan M. Christner, Jan Hendrik Beumer, Charles Kunos, Aman Khurana, Riham El Khouli, Heidi Weiss, Donglin Yan, Heloisa P. Soares, Thorvardur Ragnar Halfdanarson, Daneng Li, William Edgar Carson, Mark B Evers, Percy Ivy, Elise C. Kohn, Larry Rubinstein, Susanne M. Arnold, Jill Kolesar, Lowell Brian Anthony, Bhavana Konda
Publikováno v:
Journal of Clinical Oncology. 41:648-648
648 Background: Radiation is a potent inducer of DNA double-strand breaks, and ribonucleotide reductase (RNR) is the rate-limiting enzyme for conversion of ribonucleoside diphosphate to deoxyribonucleotide diphosphate, and thus repair of DNA in this
Autor:
Aman Chauhan, Jill Kolesar, Donglin Yan, Daneng Li, Aman Khurana, William Edgar Carson, Susanne M. Arnold, Steven Gore, Larry Rubinstein, Elise C. Kohn, Percy Ivy, Ying Xiao, Yuni Dewaraja, Heloisa P. Soares, Jan Hendrik Beumer, Bhavana Konda, Vineeth Sukrithan, Lowell Brian Anthony
Publikováno v:
Journal of Clinical Oncology. 41:TPS658-TPS658
TPS658 Background: Radiolabeled somatostatin analogues provide a means of delivering targeted radiation with a high therapeutic index to NETs that express somatostatin receptors (SSTRs). Radiolabeled somatostatin analogue Lutetium 177 DOTATATE (Lutat
Autor:
Dwight Hall Owen, Brooke Benner, Lai Wei, Vineeth Sukrithan, Ashima Goyal, Ye Zhou, Sheryl-Ann Suffren, Carly Pilcher, Gwen Christenson, Nancy Curtis, Himanshu Savardekar, Ruthann Norman, Sarah Ferguson, Barbara Kleiber, Robert Wesolowski, William Edgar Carson, Gregory Alan Otterson, Claire F. Verschraegen, Manisha H. Shah, Bhavana Konda
Publikováno v:
Journal of Clinical Oncology. 40:4121-4121
4121 Background: Treatment options are limited in patients with metastatic NEN. Temozolomide (TEM) alone and in combination with capecitabine is active in NEN and has been shown to have immunomodulatory impact. Here we present the final results for t
Autor:
Vineeth Sukrithan, Brooke Benner, Lai Wei, Ashima Goyal, Ye Zhou, Sheryl-Ann Suffren, Carly Pilcher, Gwen Christenson, Nancy Curtis, Emily Schwarz, Himanshu Savardekar, Ruthann Norman, Barbara Kleiber, Robert Wesolowski, Gregory Alan Otterson, Claire F. Verschraegen, William Edgar Carson, Manisha H. Shah, Bhavana Konda, Dwight Hall Owen
Publikováno v:
Journal of Clinical Oncology. 40:4123-4123
4123 Background: LAG-3 is an immune checkpoint present on NK cells, activated T cells and myeloid cells that inhibit T cell responses. Recent evidence demonstrating the safety and efficacy of LAG-3 inhibition has increased interest in this pathway fo
Autor:
Kari Lynn Kendra, James Moon, Zeynep Eroglu, Siwen Hu-Lieskovan, William Edgar Carson, David A. Wada, Jose A Plaza, Gino Kim In, Alexandra Ikeguchi, John Robert Hyngstrom, Andrew Scott Brohl, Bartosz Chmielowski, Nikhil I. Khushalani, Joseph Markowitz, Marcus Monroe, Kenneth F. Grossmann, Vernon K. Sondak, Elad Sharon, Michael Wu, Antoni Ribas
Publikováno v:
Journal of Clinical Oncology. 40:9502-9502
9502 Background: Desmoplastic melanoma (DM) is a rare cancer defined by a dense fibrous collagen matrix. It is associated with high UV exposure leading to a high mutational load. When locally advanced, the standard of care is wide excision and radiat
Publikováno v:
Journal of Clinical Oncology. 40:572-572
572 Background: Effective therapies for patients with non-muscle invasive bladder cancer that recurs or progresses after Bacille Calmette-Guérin (BCG) are lacking. This unmet need is the focus of many drug development efforts, reflected in many comp
Autor:
Merchand-Reyes, Giovanna, Bull, Mikayla F., Santhanam, Ramasamy, Valencia-Pena, Maria L., Murugesan, Rakesh A., Chordia, Aadesh, Mo, Xiaokui-Molly, Robledo-Avila, Frank H., De Dios Ruiz-Rosado, Juan, Carson III, William Edgar, Byrd, John C., Woyach, Jennifer A., Tridandapani, Susheela, Butchar, Jonathan P.
Publikováno v:
Frontiers in Immunology; 2024, p1-14, 14p
Publikováno v:
Health & Medicine Week; 7/26/2024, p4346-4346, 1p
Autor:
Sacchi, Alessandra, Tumino, Nicola, Sabatini, Andrea, Cimini, Eleonora, Casetti, Rita, Bordoni, Veronica, Grassi, Germana, Agrati, Chiara
Publikováno v:
Frontiers in Immunology; 6/6/2018, p1-9, 9p