Zobrazeno 1 - 10
of 15
pro vyhledávání: '"William E. Grever"'
Autor:
Elizabeth R. Sharlow, Danielle C. Llaneza, William E. Grever, Garnett A. Mingledorff, Anna J. Mendelson, George S. Bloom, John S. Lazo
Publikováno v:
SLAS Discovery, Vol 28, Iss 6, Pp 275-283 (2023)
Human induced pluripotent stem cell (iPSC)-derived neurons are being increasingly used for high content imaging and screening. However, iPSC-derived neuronal differentiation and maturation is time-intensive, often requiring >8 weeks. Unfortunately, t
Externí odkaz:
https://doaj.org/article/d14cfbcac61844679a8e3bf159917758
Autor:
Elizabeth R. Sharlow, Danielle C. Llaneza, William E. Grever, Garnett A. Mingledorff, Anna J. Mendelson, George S. Bloom, John S. Lazo
Publikováno v:
SLAS Discovery.
Human induced pluripotent stem cell (iPSC)-derived neurons are being increasingly used for high content imaging and screening. However, iPSC-derived neuronal differentiation and maturation is time-intensive, often requiring8 weeks. Unfortunately, the
Autor:
James D Tucker, George W Divine, William E Grever, Robert A Thomas, Michael C Joiner, Joseph M Smolinski, Gregory W Auner
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83390 (2013)
Rapid and reliable methods for performing biological dosimetry are of paramount importance in the event of a large-scale nuclear event. Traditional dosimetry approaches lack the requisite rapid assessment capability, ease of use, portability and low
Externí odkaz:
https://doaj.org/article/3b5a78703de94533b104184f311d8063
Autor:
James D. Tucker, Michael C. Joiner, Marina V. Bakhmutsky, Robert A. Thomas, George Divine, Chantelle N. Chinkhota, Joseph M. Smolinski, William E. Grever, Gregory W. Auner
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 88:933-939
Purpose Rapid and reliable methods for conducting biological dosimetry are a necessity in the event of a large-scale nuclear event. Conventional biodosimetry methods lack the speed, portability, ease of use, and low cost required for triaging numerou
Autor:
Robert A. Thomas, Andre Konski, Michael C. Joiner, James D. Tucker, George Divine, William E. Grever, Gregory W. Auner, Joseph M. Smolinski
Publikováno v:
Radiation Research. 177:209-219
In a large-scale nuclear incident, many thousands of people may be exposed to a wide range of radiation doses. Rapid biological dosimetry will be required on an individualized basis to estimate the exposures and to make treatment decisions. To amelio
Publikováno v:
Journal of Neurochemistry. 77:1027-1035
Defensins are cationic peptides with broad-spectrum antimicrobial activity. They are members of a supergene family consisting of alpha and beta subtypes and each subtype is comprised of a number of different isoforms. For example, human alpha-defensi
Autor:
Robert A. Thomas, Michael C. Joiner, Joseph M. Smolinski, James D. Tucker, George Divine, Gregory W. Auner, William E. Grever
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e83390 (2013)
PLoS ONE, Vol 8, Iss 12, p e83390 (2013)
Rapid and reliable methods for performing biological dosimetry are of paramount importance in the event of a large-scale nuclear event. Traditional dosimetry approaches lack the requisite rapid assessment capability, ease of use, portability and low
Publikováno v:
Molecular Medicine Today. 3:554-561
Myelin disorders form an important group of human neurological diseases that are as yet incurable. Recent studies on experimental remyelination have suggested that it might be feasible to repair the CNS, either by transplanting normal myelinating cel
Autor:
William E. Grever, Karen M. Weidenheim, William D. Lyman, Marianela Tricoche, William K. Rashbaum
Publikováno v:
Journal of Neuroscience Research. 47:332-340
A comprehensive evaluation of myelination during normal human development is essential to understand the pathology of congenital diseases of white matter. The present study establishes quantitative values for normal oligodendrocyte-specific gene expr
Autor:
William D. Lyman, Marianela Tricoche, Karen M. Weidenheim, Fung Chow Chiu, William E. Grever, William K. Rashbaum
Publikováno v:
The Journal of Comparative Neurology. 376:306-314
The amount of myelin basic protein (MBP) was quantified in human fetal spinal cords from 12 to 24 gestational weeks (GW). MBP expression was determined by Northern blot, quantitative immunoblot, and immunocytochemistry. The development of compact mye