Zobrazeno 1 - 10
of 334
pro vyhledávání: '"William E. Fisher"'
Autor:
Christian Marin-Muller, Dali Li, Jian-Ming Lü, Zhengdong Liang, Osvaldo Vega-Martínez, Sue E. Crawford, Mary K. Estes, William E. Fisher, Changyi Chen, Qizhi Yao
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2038 (2023)
Pancreatic ductal adenocarcinoma (PDAC) remains an extremely aggressive disease characterized by rapidly acquired multi-drug resistance, including to first-line chemotherapeutic agent gemcitabine. Autophagy is a process that is often exploited by can
Externí odkaz:
https://doaj.org/article/f116cb6dc4b44b109840462a44d78046
Autor:
Katherine A. Baugh, Svetang Desai, George Van Buren 2nd, William E. Fisher, Carlos A. Farinas, Sadhna Dhingra
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Amyloid deposition in pancreas is rare. Lactoferrin amyloid deposition has not been reported in pancreas, till date. Presence of enhancing mural nodule in a cyst on imaging is a worrisome feature for malignancy, and warrants surgi
Externí odkaz:
https://doaj.org/article/e0b587f39442430ab39b80b1d1df7de1
Autor:
Sheng Pan, Randall E. Brand, Lisa A. Lai, David W. Dawson, Timothy R. Donahue, Stephen Kim, Natalia I. Khalaf, Mohamed O. Othman, William E. Fisher, Mary P. Bronner, Diane M. Simeone, Teresa A. Brentnall, Ru Chen
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 8, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/133a96f1baab4371b9b970b0d84c49f8
Autor:
John M. Baust, Kimberly L. Santucci, Robert G. Van Buskirk, Isaac Raijman, William E. Fisher, John G. Baust, Kristi K. Snyder
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 450 (2022)
As the incidence of pancreatic ductal adenocarcinoma (PDAC) continues to grow, so does the need for new strategies for treatment. One such area being evaluated is cryoablation. While promising, studies remain limited and questions surrounding basic d
Externí odkaz:
https://doaj.org/article/3e0043fabb1947798d4a2dda19460925
Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation
Autor:
Marie-Claude Gingras, Kyle R. Covington, David K. Chang, Lawrence A. Donehower, Anthony J. Gill, Michael M. Ittmann, Chad J. Creighton, Amber L. Johns, Eve Shinbrot, Ninad Dewal, William E. Fisher, Christian Pilarsky, Robert Grützmann, Michael J. Overman, Nigel B. Jamieson, George Van Buren II, Jennifer Drummond, Kimberly Walker, Oliver A. Hampton, Liu Xi, Donna M. Muzny, Harsha Doddapaneni, Sandra L. Lee, Michelle Bellair, Jianhong Hu, Yi Han, Huyen H. Dinh, Mike Dahdouli, Jaswinder S. Samra, Peter Bailey, Nicola Waddell, John V. Pearson, Ivon Harliwong, Huamin Wang, Daniela Aust, Karin A. Oien, Ralph H. Hruban, Sally E. Hodges, Amy McElhany, Charupong Saengboonmee, Fraser R. Duthie, Sean M. Grimmond, Andrew V. Biankin, David A. Wheeler, Richard A. Gibbs
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 907-919 (2016)
The ampulla of Vater is a complex cellular environment from which adenocarcinomas arise to form a group of histopathologically heterogenous tumors. To evaluate the molecular features of these tumors, 98 ampullary adenocarcinomas were evaluated and co
Externí odkaz:
https://doaj.org/article/ed03ea58619548d2aee7acfa83a8cd5c
Autor:
Yuqing Zhang, Jingxuan Yang, Xiaobo Cui, Yong Chen, Vivian F. Zhu, John P. Hagan, Huamin Wang, Xianjun Yu, Sally E. Hodges, Jing Fang, Paul J. Chiao, Craig D. Logsdon, William E. Fisher, F. Charles Brunicardi, Changyi Chen, Qizhi Yao, Martin E. Fernandez‐Zapico, Min Li
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 9, Pp 1322-1334 (2013)
Abstract Changes in the intracellular levels of the essential micronutrient zinc have been implicated in multiple diseases including pancreatic cancer; however, the molecular mechanism is poorly understood. Here, we report a novel mechanism where inc
Externí odkaz:
https://doaj.org/article/238097a73c684b9a9aef908dd7f6c43e
Autor:
William E. Fisher M.D.
Publikováno v:
Cell Transplantation, Vol 8 (1999)
It is difficult to normalize plasma glucose for a prolonged period of time by SC injection in experimental animals. The goal of this study was to determine the feasibility and the dosage of insulin needed to maintain 24-h normoglycemia in streptozoto
Externí odkaz:
https://doaj.org/article/f33868c9a9374b0e8a9479564097965a
Autor:
Naveen Manisundaram, Jorge I Portuondo, Derek Erstad, Eric Silberfein, Cary Hsu, Omar Barakat, Amy Wood, Martina Navarro-Cagigas, George Van Buren, William E Fisher, E Ramsay Camp
Publikováno v:
Journal of the American College of Surgeons. 236:861-870
Development of a Clinical Prediction Model for Diabetes in Chronic Pancreatitis: The PREDICT3c Study
Autor:
Christie Jeon, Phil A. Hart, Liang Li, Yunlong Yang, Eleanor Chang, Melena D. Bellin, William E. Fisher, Evan L. Fogel, Christopher E. Forsmark, Walter G. Park, Stephen K. Van Den Eeden, Santhi Swaroop Vege, Jose Serrano, David C. Whitcomb, Dana K. Andersen, Darwin L. Conwell, Dhiraj Yadav, Mark O. Goodarzi
Publikováno v:
Diabetes Care. 46:46-55
OBJECTIVE Diabetes that arises from chronic pancreatitis (CP) is associated with increased morbidity and mortality. Methods to predict which patients with CP are at greatest risk for diabetes are urgently needed. We aimed to examine independent risk
Autor:
Phil A. Hart, Stephen J. Pandol, Dhiraj Yadav, William E. Fisher, Santhi Swaroop Vege, Evan L. Fogel, Chris E. Forsmark, Darwin L. Conwell, Mark Topazian, Jose Serrano, David Bradley, Stephen K Van Den Eden, Walter G. Park, Savi Appana, Liang Li
Publikováno v:
Clinical Gastroenterology and Hepatology. 20:2005-2013
Background & Aims Chronic pancreatitis (CP) is associated with osteopathy (osteoporosis or osteopenia). However, existing literature is mostly limited to retrospective or administrative studies that have not clearly defined the prevalence and risk fa