Zobrazeno 1 - 10
of 10
pro vyhledávání: '"William E. Briley"'
Publikováno v:
Spherical Nucleic Acids ISBN: 9780429200151
Spherical Nucleic Acids ISBN: 9781003056713
Spherical Nucleic Acids ISBN: 9781003056713
We report a novel spherical nucleic acid (SNA) gold nanoparticle conjugate, termed the Sticky-flare, which enables facile quantification of RNA expression in live cells and spatiotemporal analysis of RNA transport and localization. The Sticky-flare i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6220e2d952b1b382001ab4764319d25
https://doi.org/10.4324/9780429200151-113
https://doi.org/10.4324/9780429200151-113
Publikováno v:
ACS Nano
Herein, we describe a rapid, divergent method for using spherical nucleic acids (SNAs) as a universal platform for attaching RNA to DNA-modified nanoparticles using enzyme-mediated techniques. This approach provides a sequence-specific method for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9d37e5682f4b6600c428474a4099b7
http://europepmc.org/articles/PMC4174098
http://europepmc.org/articles/PMC4174098
Publikováno v:
Journal of the American Chemical Society. 136:7261-7264
Nanoparticles of a metal-organic framework (MOF), UiO-66-N3 (Zr6O4OH4(C8H3O4-N3)6), were synthesized. The surface of the MOF was covalently functionalized with oligonucleotides, utilizing a strain promoted click reaction between DNA appended with dib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac52467d01bc1f5103ce37b4fb7293b7
https://doi.org/10.1021/ja503215w
https://doi.org/10.1021/ja503215w
Gene delivery to overcome astrocyte inhibition of axonal growth: An in vitro Model of the glial scar
Publikováno v:
Biotechnology and Bioengineering. 110:947-957
After injury to the central nervous system, a glial scar develops that physically and biochemically inhibits axon growth. In the scar, activated astrocytes secrete inhibitory extracellular matrix, of which chondroitin sulfate proteoglycans (CSPGs) ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf6916ac112b6897155472cc8d2e987
https://doi.org/10.1002/bit.24750
https://doi.org/10.1002/bit.24750
Autor:
Andrew E. Prigodich, David A. Giljohann, Weston L. Daniel, William E. Briley, Nathaniel Kim, Pratik S. Randeria, Chad A. Mirkin
Publikováno v:
Analytical Chemistry. 84:2062-2066
We report the development of the multiplexed nanoflare, a nanoparticle agent that is capable of simultaneously detecting two distinct mRNA targets inside a living cell. These probes are spherical nucleic acid (SNA) gold nanoparticle (Au NP) conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd55e340f0aaac43f5eb7b7c693b2bbd
https://doi.org/10.1021/ac202648w
https://doi.org/10.1021/ac202648w
Autor:
Fotini M. Kouri, Jessica L. Rouge, William E. Briley, Timothy L. Sita, Chad A. Mirkin, Alexander H. Stegh, Liangliang Hao
Publikováno v:
Journal of the American Chemical Society. 137(33)
Ribozymes are highly structured RNA sequences that can be tailored to recognize and cleave specific stretches of mRNA. Their current therapeutic efficacy remains low due to their large size and structural instability compared to shorter therapeutical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574a2dc91e921a3ca287fe96fa1a533a
https://pubmed.ncbi.nlm.nih.gov/26271335
https://pubmed.ncbi.nlm.nih.gov/26271335
Autor:
Pratik S, Randeria, William E, Briley, Alyssa B, Chinen, Chenxia M, Guan, Sarah Hurst, Petrosko, Chad A, Mirkin
Publikováno v:
Cancer treatment and research. 166
Patients whose cancer is detected early are much more likely to have a positive prognosis and outcome. Nanoflares hold promise as a practical diagnostic platform for the early detection of cancer markers in living cells. These probes are based on sph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83130d91d3bc1f357e2258e6568c6f0f
https://pubmed.ncbi.nlm.nih.gov/25895862
https://pubmed.ncbi.nlm.nih.gov/25895862
Autor:
Chad A. Mirkin, William E. Briley, Alyssa B. Chinen, Sarah Hurst Petrosko, Pratik S. Randeria, Chenxia M. Guan
Publikováno v:
Cancer Treatment and Research ISBN: 9783319165547
Patients whose cancer is detected early are much more likely to have a positive prognosis and outcome. Nanoflares hold promise as a practical diagnostic platform for the early detection of cancer markers in living cells. These probes are based on sph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd9a7a938065b96a03b63e77d0ff0d13
https://doi.org/10.1007/978-3-319-16555-4_1
https://doi.org/10.1007/978-3-319-16555-4_1
Autor:
Colin M. Calabrese, Timothy J. Merkel, William E. Briley, Pratik S. Randeria, Suguna P. Narayan, Jessica L. Rouge, David A. Walker, Alexander W. Scott, Chad A. Mirkin
Publikováno v:
Angewandte Chemie International Edition.
Herein, we report the synthesis of DNA-functionalized infinite-coordination-polymer (ICP) nanoparticles as biocompatible gene-regulation agents. ICP nanoparticles were synthesized from ferric nitrate and a ditopic 3-hydroxy-4-pyridinone (HOPO) ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f7ed30a6ca361205e25822f486cf97
https://doi.org/10.1002/anie.201407946
https://doi.org/10.1002/anie.201407946
Autor:
Sarah J. Hurst, Pratik S. Randeria, Evelyn Auyeung, William E. Briley, Ali H. Alhasan, Tiffany L. Halo, Chad A. Mirkin
Publikováno v:
ACS Symposium Series ISBN: 9780841227187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2462081751a9deb53a4ef3e44d1d8a07
https://doi.org/10.1021/bk-2012-1119.ch001
https://doi.org/10.1021/bk-2012-1119.ch001