Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William E. Bondinell"'
Autor:
Irene N. Uzinskas, Kyung O. Johanson, William F. Huffman, R. D. Cousins, William E. Bondinell, Stephen T. Ross, M.W. Lark, Keith W. Ward, Chuan-Kui Yuan, Kevin L. Salyers, Dirk A. Heerding, S M Hwang, Joseph W. Venslavsky, J. Samanen, Karl F. Erhard, Raul R. Calvo, M. Gowen, Pradip K. Bhatnagar, James F. Callahan, Manley Peter J, Doreen Alberts, Brian R. Smith, Kenneth A. Newlander, W.H. Miller, R. C. Haltiwanger, Richard M. Keenan, George B. Stroup, David J. Rieman, Chet Kwon, Leonard M. Azzarano, Ian E. James
Publikováno v:
Journal of Medicinal Chemistry. 43:22-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921ed25c145b5edbd1b8a614916fc7cc
https://doi.org/10.1021/jm990446u
https://doi.org/10.1021/jm990446u
Autor:
Philip L. Smith, A. Nichols, Thomas W. Ku, William E. Bondinell, Glynn Wilson, J. Samanen, Chao-Pin Lee, Gerald R. Rhodes
Publikováno v:
Journal of Pharmacy and Pharmacology. 48:119-135
This review discusses both tools and strategies that may be employed as approaches towards the pursuit of orally active compounds from peptidergic molecules. Besides providing a review of these subjects, this paper provides an example of how these we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af741b2c0bab50ac96bb650166aff3c
https://doi.org/10.1111/j.2042-7158.1996.tb07111.x
https://doi.org/10.1111/j.2042-7158.1996.tb07111.x
Autor:
Kenneth A. Newlander, Chet Kwon, William F. Huffman, Richard M. Keenan, Leon B. Hall, James Samanen, Chuan-Kui Yuan, T. W. Ku, William E. Bondinell, F. E. Ali, Karl F. Erhard, Raul R. Calvo, William H. Miller, Larry D. Davis, Dennis T. Takata, Stephen T. Ross
Publikováno v:
Tetrahedron Letters. 36:9433-9436
An enantiospecific synthesis of SB 214857, a potent, nonpeplide fibrinogen receptor antagonist, is reported. The synthetic route employs as a key step an intramolecular aryl fluoride displacement to form the sevenmembered ring of the 1,4-benzodiazepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e020141c650769ae0d556a7deb7f5124
https://doi.org/10.1016/0040-4039(95)02054-3
https://doi.org/10.1016/0040-4039(95)02054-3
Autor:
Karl F. Erhard, Andreas Klos, G. McCafferty, J. P. Hieble, Osborn Rr, A.C. Sulpizio, Alison M. Badger, Underwood Dc, Robert S. Ames, Adams Jl, James J. Foley, Wilfried Bautsch, R. D. Cousins, Keith W. Ward, William E. Bondinell, A. J. Jurewicz, Mark A. Tornetta, B. Settmacher, David Lee, Henry M. Sarau
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 166(10)
The anaphylatoxin C3a is a potent chemotactic peptide and inflammatory mediator released during complement activation which binds to and activates a G-protein-coupled receptor. Molecular cloning of the C3aR has facilitated studies to identify nonpept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b45efdd6adabf3869da39630f22ba9
https://pubmed.ncbi.nlm.nih.gov/11342658
https://pubmed.ncbi.nlm.nih.gov/11342658
Autor:
Don E. Griswold, William E. Bondinell, Marie Chabot-Flecher, Floyd H. Chilton, Lisa A. Marshall, Ruth J. Mayer, James D. Winkler, Chiu-Mei Sung
Publikováno v:
Molecular pharmacology. 53(2)
The enzyme coenzyme A-independent transacylase (CoA-IT) has been demonstrated to be the key mediator of arachidonate remodeling, a process that moves arachidonate into 1-ether-containing phospholipids. Blockade of CoA-IT by reversible inhibitors has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34074954a584df040419da9541d216f5
https://pubmed.ncbi.nlm.nih.gov/9463491
https://pubmed.ncbi.nlm.nih.gov/9463491
Autor:
A. Nichols, S M Hwang, Richard J. Simpson, Chet Kwon, J. Samanen, Gerald R. Rhodes, Richard Heys, Dalia R. Jakas, William E. Bondinell, Giora Zeev Feuerstein, William F. Huffman, Irene Uzsinskas, Joseph W. Venslavsky, Catherine E. Peishoff, Thomas W. Ku, Joelle Lorraine Burgess, Wenting Chen, Richard M. Keenan, Kenneth A. Newlander, Fadia E. Ali, Chuan-Kui Yuan, Lichong Chen, Chao-Pin Lee, Steven T. Ross, Michael W. Parker, Arthur Shu, Karl F. Erhard, Raul R. Calvo, T. Yellin, William H. Miller, Linda S. Barton, Dennis T. Takata, James F. Callahan
Publikováno v:
Journal of medicinal chemistry. 39(25)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb2a7675c4347a9adcf9711758a2e20
https://pubmed.ncbi.nlm.nih.gov/8960544
https://pubmed.ncbi.nlm.nih.gov/8960544
Autor:
Andrew J. Nichols, Angela S. Wong, Richard M. Keenan, James Samanen, William E. Bondinell, Thomas W. Ku, William H. Miller, Karl F. Erhard, Catherine E. Peishoff, William F. Huffman
Publikováno v:
Journal of medicinal chemistry. 38(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de70ad0157e10a120326f38040e17731
https://pubmed.ncbi.nlm.nih.gov/7837245
https://pubmed.ncbi.nlm.nih.gov/7837245
Design of a potent and orally active nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist
Autor:
Drake S. Eggleston, Angela S. Wong, Andrew J. Nichols, Chuan-Kui Yuan, R. Curtis Haltiwanger, William E. Bondinell, Paul F. Koster, William H. Miller, Joseph W. Venslavsky, William F. Huffman, Karl F. Erhard, S M Hwang, Janice A. Vasko-Moser, Thomas W. Ku, Chao Pin Lee, Stephen T. Ross, Dalia R. Jakas, Richard M. Keenan, J. Samanen, Richard E. Valocik, Charles W. De Brosse, Fadia E. Ali, Andrew Allen
Publikováno v:
Bioorganicmedicinal chemistry. 2(9)
The direct design of the potent nonpeptide platelet fibrinogen receptor (GPIIb/IIIa) antagonist, 8-[[[4- (aminoiminomethyl)phenyl]amino]carbonyl]-2,3,4,5-tetrahydro-3-oxo- 4- (2-phenylethyl)-1H-1,4-benzodiazepine-2-acetic acid, (3) (SB 207448), based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247132c8d3e49be06ba5bb125e0be644
https://pubmed.ncbi.nlm.nih.gov/7712125
https://pubmed.ncbi.nlm.nih.gov/7712125
Autor:
Joelle Lorraine Burgess, Lichong Chen, Linda S. Barton, John W. Bean, Raul R. Calvo, James F. Callahan, William E. Bondinell, Fadia E. Ali, Thomas W. Ku
Publikováno v:
Journal of the American Chemical Society. 115:8861-8862
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b5a3b4f6a49b38c8d3dc51e4f0625b
https://doi.org/10.1021/ja00072a058
https://doi.org/10.1021/ja00072a058
Publikováno v:
European Journal of Pharmacology. 183:1204-1205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3aab3b5de1a2ccfb9c0bb938390bec8
https://doi.org/10.1016/0014-2999(90)94299-d
https://doi.org/10.1016/0014-2999(90)94299-d