Zobrazeno 1 - 10
of 36
pro vyhledávání: '"William E. Ballinger"'
Autor:
Peter J. Oates, Jian-Cheng Li, David A. Beebe, R. Matthew Weekly, Day Wesley Warren, Margaret Y. Chu-Moyer, William E. Ballinger, James B. Coutcher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:1477-1480
SAR studies on the stereoisomers of CP-470,711 suggested that in vivo epimerization was taking place in rats. Further metabolism studies revealed that no epimerization was occurring in dogs, and that no epimerization was expected in humans. A mechani
Publikováno v:
Survey of Ophthalmology. 39:315-322
A 65-year-old white woman developed progressive visuospatial abnormalities over an eight-year course, secondary to Alzheimer's disease with amyloid angiopathy. Imaging studies demonstrated focal atrophy of the parietal and occipital lobes without hem
Publikováno v:
Epilepsy Research. 12:261-265
Chronic administration of the experimental antiepileptic drug vigabatrin (gamma-vinyl GABA) to animals has been shown to cause dose-dependent neuropathological changes characterized by a microvacuolation in specific white matter tracts. This finding
Autor:
Gerhard Freund, William E. Ballinger
Publikováno v:
Alcohol. 9:233-240
The purpose of this investigation was to test the hypothesis that chronic exposure to alcohol may accelerate Alzheimer's disease (AD), either by independently adding receptor losses or by accelerating the AD disease process itself. Muscarinic [3H]qui
Autor:
Albert L. Rhoton, Robert B. Marcus, Rodney R. Million, William E. Ballinger, W. Mark McCollough
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 21:607-614
Recent literature has suggested that late recurrence of pituitary adenoma after radiotherapy is common. We hypothesized that late failures might be a result of inadequate dose (less than 4500 cGy). To investigate, we analyzed 105 patients treated at
Publikováno v:
Stereotactic and Functional Neurosurgery. 56:166-178
Nucleus caudalis dorsal root entry zone lesions (open trigeminal nucleotomy) are a surgical procedure which can achieve pain control without major complications in the difficult clinical setting of deafferentation-type facial pain. Two patients are r
Autor:
Day Wesley Warren, David A. Beebe, Margaret Y. Chu-Moyer, William E. Ballinger, Peter J. Oates, Banavara L. Mylari, Jiancheng Li, James B. Coutcher, Richard Berger, R. Matthew Weekly
Publikováno v:
Journal of medicinal chemistry. 45(2)
Optimization of a previously disclosed sorbitol dehydrogenase inhibitor (SDI, II) for potency and duration of action was achieved by replacing the metabolically labile N,N-dimethylsulfamoyl group with a variety of heterocycles. Specifically, this eff
Autor:
James T. Symanowski, Renee P Kelly, Ashley Sumrall, Mark D Smith, Stuart H. Burri, Peggy O Boltes, Daniel Haggstrom, Roshan S. Prabhu, Robert Fraser, Anthony L. Asher, William E Ballinger
Publikováno v:
Journal of Clinical Oncology. 32:2069-2069
2069 Background: Radiation therapy (RT) and concurrent temozolomide (CRT) is the accepted standard for newly diagnosed glioblastoma (GBM). Despite promising results in recurrent settings, addition ...
Autor:
William E. Ballinger, Richard L. White, Brent D. Matthews, B. Todd Heniford, Cynthia D. Nelms, Ronald F. Sing
Publikováno v:
Journal of the American College of Surgeons. 194:674-675
Autor:
Gerhard Freund, William E. Ballinger
Publikováno v:
Alcohol. 5:275-282
We hypothesize that chronic alcohol abuse results in a loss of neurons and their associated synaptic receptors. This encephalopathy may be a precursor of brain atrophy and end-stage dementia. Autopsies were performed on normal brains of 27 alcoholics