Výsledky vyhledávání - "William E. Askew"

Cerebellar cAMP levels following acute and chronic morphine administration

Autor: William E. Askew, K. D. Charalampous

Publikováno v: Canadian Journal of Physiology and Pharmacology. 55:117-120

Acute administration of morphine sulfate at 20 mg/kg decreased mouse cerebellar adenosine 3′,5′-cyclic phosphate (cAMP) levels while not affecting cAMP phosphodiesterase (EC 3.1.4.17). The cAMP levels and cAMP phosphodiesterase activities were no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003754528982e10b235cc5e7e68064c0
https://doi.org/10.1139/y77-017

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Chronic ethanol and neural C-AMP

Autor: K.D. Charalampous, William E. Askew

Publikováno v: Life Sciences. 22:639-646

Ethanol was administered chronically to Swiss albino mice via an inhalation chamber utilizing two models, the pyrazole model of Goldstein and the non-pyrazole model of Griffiths et al. C-AMP, adenylate cyclase, and phosphodiesterase levels were analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a48b75f9957f58991abb81b913351af
https://doi.org/10.1016/0024-3205(78)90485-x

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Effects of 6-methoxy-1,2,3,4-tetrahydro-β-carboline on the regional and subcellular distribution of serotonin in mouse and rat brains

Autor: William E. Askew, William M. McIsaac, Dorothy Taylor, Beng T. Ho

Publikováno v: Life Sciences. 11:493-502

6-Methoxy-1,2,3,4-tetrahydro-β-carboline (6-MeO-THBC), which exerts its effect specifically on brain serotonin (5-HT), caused substantial increase of the amine in all the discrete areas of the rat brain. Since norepinephrine levels were unchanged, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a1a0ee37cb7fb7a18c8dc4c534a25f
https://doi.org/10.1016/0024-3205(72)90199-3

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Effects of Intraventricular Injections of N6,O2′-Dibutyryl Adenosine 3′,5′-Monophosphate on the Rat Brain Cholinergic System

Autor: Beng T. Ho, William E. Askew

Publikováno v: Canadian Journal of Biochemistry. 53:634-635

Intraventricular injections of dibutyryl cyclic AMP effected increases of acetylcholine in the cerebral cortex – striatal and subcortical regions. No increase in choline acetyltransferase activity was observed; however, there was a significant decr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe1ab9c0d8ddc3f22e7c386b325afa2
https://doi.org/10.1139/o75-086

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