Zobrazeno 1 - 10
of 91
pro vyhledávání: '"William E Theurkauf"'
Autor:
Julianna Bozler, Balint Z Kacsoh, Hao Chen, William E Theurkauf, Zhiping Weng, Giovanni Bosco
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007054 (2017)
The ability to integrate experiential information and recall it in the form of memory is observed in a wide range of taxa, and is a hallmark of highly derived nervous systems. Storage of past experiences is critical for adaptive behaviors that antici
Externí odkaz:
https://doaj.org/article/adddb8ccd1284fe5b34180519af59ac9
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001246 (2010)
Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway
Externí odkaz:
https://doaj.org/article/5bbba711748a4dd0bb2bd7d5458251da
Autor:
Klaus Förstemann, Yukihide Tomari, Tingting Du, Vasily V Vagin, Ahmet M Denli, Diana P Bratu, Carla Klattenhoff, William E Theurkauf, Phillip D Zamore
Publikováno v:
PLoS Biology, Vol 3, Iss 7, p e236 (2005)
microRNAs (miRNAs) are single-stranded, 21- to 23-nucleotide cellular RNAs that control the expression of cognate target genes. Primary miRNA (pri-miRNA) transcripts are transformed to mature miRNA by the successive actions of two RNase III endonucle
Externí odkaz:
https://doaj.org/article/f4a0cad3bdc04420b93e7f0e7932bd6e
Autor:
Jichuan Cao, Tianxiong Yu, Bo Xu, Zhongren Hu, Xiao-ou Zhang, William E Theurkauf, Zhiping Weng
Publikováno v:
Nucleic Acids Research. 51:2066-2086
Transposons are mobile genetic elements prevalent in the genomes of most species. The distribution of transposons within a genome reflects the actions of two opposing processes: initial insertion site selection, and selective pressure from the host.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::988cd6a3cfb4cac349318f136bb3a420
https://doi.org/10.1093/nar/gkad054
https://doi.org/10.1093/nar/gkad054
Autor:
Tianxiong Yu, Zhiping Weng, William E. Theurkauf, Swapnil S. Parhad, Nicholas P. Rice, Gen Zhang
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2672-2685.e5 (2020)
Cell reports
Cell reports
SUMMARY In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c8a087e01326467065a8dd66b23505
http://www.sciencedirect.com/science/article/pii/S2211124720301534
http://www.sciencedirect.com/science/article/pii/S2211124720301534
Autor:
Junko Tsuji, Travis Thomson, Christine Brown, Subhanita Ghosh, William E. Theurkauf, Zhiping Weng, Lawrence M. Schwartz
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics, Vol 12 (2021)
PIWI-interacting RNAs (piRNAs) are small single-stranded RNAs that can repress transposon expression via epigenetic silencing and transcript degradation. They have been identified predominantly in the ovary and testis, where they serve essential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ff7c022ea38dd99f63e64f0e1fa531
https://pubmed.ncbi.nlm.nih.gov/35003216
https://pubmed.ncbi.nlm.nih.gov/35003216
Autor:
Christine Brown, Lawrence M. Schwartz, Travis Thomson, Zhiping Weng, William E. Theurkauf, Junko Tsuji, Subhanita Ghosh
PiWi-interacting RNAs (piRNAs) are small single-stranded RNAs that can repress transposon expression via epigenetic silencing and transcript degradation. They have been identified predominantly in the ovary and testis, where they serve essential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::484404b3a78611b433d2913271496057
https://doi.org/10.1101/2021.03.02.433533
https://doi.org/10.1101/2021.03.02.433533
Publikováno v:
Dev Cell
piRNAs guide Piwi/Panoramix-dependent H3K9me3 chromatin modification and transposon silencing during Drosophila germline development. The THO RNA export complex is composed of Hpr1, Tho2, and Thoc5–7. Null thoc7 mutations, which displace Thoc5 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542efec2e14493a2dbaaa8db0db4cf83
https://pubmed.ncbi.nlm.nih.gov/34547226
https://pubmed.ncbi.nlm.nih.gov/34547226
Autor:
Zhiping Weng, Gen Zhang, Tianxiong Yu, Yu Fu, Deniz M. Ozata, Kaili Fan, William E. Theurkauf, Phillip D. Zamore
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
In the male germ cells of placental mammals, 26–30-nt-long PIWI-interacting RNAs (piRNAs) emerge when spermatocytes enter the pachytene phase of meiosis. In mice, pachytene piRNAs derive from ~100 discrete autosomal loci that produce canonical RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e802fe5e69e486d060c8b435e10dc8
https://doi.org/10.1038/s41467-020-20345-3
https://doi.org/10.1038/s41467-020-20345-3
Autor:
Xianjun Dong, Elizabeth Chan, Zhiping Weng, Christine Brown, Junko Tsuji, William E. Theurkauf, Julia Oppenheimer, Carol Bigelow, Travis Thomson, Lawrence M. Schwartz
Publikováno v:
Physiol Genomics
Skeletal muscles can undergo atrophy and/or programmed cell death (PCD) during development or in response to a wide range of insults, including immobility, cachexia, and spinal cord injury. However, the protracted nature of atrophy and the presence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8002c7e335b78402888cb4151a0802
https://pubmed.ncbi.nlm.nih.gov/32926651
https://pubmed.ncbi.nlm.nih.gov/32926651