Zobrazeno 1 - 10
of 140
pro vyhledávání: '"William E Theurkauf"'
Autor:
Tianxiong Yu, Kaili Fan, Deniz M. Özata, Gen Zhang, Yu Fu, William E. Theurkauf, Phillip D. Zamore, Zhiping Weng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The pachytene piRNA loci are transcribed by RNA polymerase II in the male germline of placental mammals. Here the authors show that a long first exon or a long unspliced transcript correlates with germline-specific production of piRNA precursor trans
Externí odkaz:
https://doaj.org/article/1760126de9e147de89acee694ee12b89
Autor:
Junko Tsuji, Travis Thomson, Christine Brown, Subhanita Ghosh, William E. Theurkauf, Zhiping Weng, Lawrence M. Schwartz
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
PIWI-interacting RNAs (piRNAs) are small single-stranded RNAs that can repress transposon expression via epigenetic silencing and transcript degradation. They have been identified predominantly in the ovary and testis, where they serve essential role
Externí odkaz:
https://doaj.org/article/885a4f5eb70e4d7c829c4646687b6d25
Autor:
Jichuan Cao, Tianxiong Yu, Bo Xu, Zhongren Hu, Xiao-ou Zhang, William E Theurkauf, Zhiping Weng
Publikováno v:
Nucleic Acids Research. 51:2066-2086
Transposons are mobile genetic elements prevalent in the genomes of most species. The distribution of transposons within a genome reflects the actions of two opposing processes: initial insertion site selection, and selective pressure from the host.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::988cd6a3cfb4cac349318f136bb3a420
https://doi.org/10.1093/nar/gkad054
https://doi.org/10.1093/nar/gkad054
Autor:
Swapnil S. Parhad, Tianxiong Yu, Gen Zhang, Nicholas P. Rice, Zhiping Weng, William E. Theurkauf
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2672-2685.e5 (2020)
Summary: In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recr
Externí odkaz:
https://doaj.org/article/3b5fc02d254a40728cf13d60ad1dac17
Publikováno v:
Open Biology, Vol 9, Iss 1 (2019)
Transposons are major genome constituents that can mobilize and trigger mutations, DNA breaks and chromosome rearrangements. Transposon silencing is particularly important in the germline, which is dedicated to transmission of the inherited genome. P
Externí odkaz:
https://doaj.org/article/386c7c714bc845618c404dad4a62620a
Autor:
Gen Zhang, Shikui Tu, Tianxiong Yu, Xiao-Ou Zhang, Swapnil S. Parhad, Zhiping Weng, William E. Theurkauf
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3413-3422.e4 (2018)
Summary: In Drosophila, the piRNAs that guide germline transposon silencing are produced from heterochromatic clusters marked by the HP1 homolog Rhino. We show that Rhino promotes cluster transcript association with UAP56 and the THO complex, forming
Externí odkaz:
https://doaj.org/article/e31bb445f28c4d8f88ceacdf809f6d65
Autor:
Julianna Bozler, Balint Z Kacsoh, Hao Chen, William E Theurkauf, Zhiping Weng, Giovanni Bosco
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007054 (2017)
The ability to integrate experiential information and recall it in the form of memory is observed in a wide range of taxa, and is a hallmark of highly derived nervous systems. Storage of past experiences is critical for adaptive behaviors that antici
Externí odkaz:
https://doaj.org/article/adddb8ccd1284fe5b34180519af59ac9
Autor:
Tianxiong Yu, Zhiping Weng, William E. Theurkauf, Swapnil S. Parhad, Nicholas P. Rice, Gen Zhang
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2672-2685.e5 (2020)
Cell reports
Cell reports
SUMMARY In Drosophila, transposon-silencing piRNAs are derived from heterochromatic clusters and a subset of euchromatic transposon insertions, which are bound by the Rhino-Deadlock-Cutoff complex. The HP1 homolog Rhino binds to Deadlock, which recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c8a087e01326467065a8dd66b23505
http://www.sciencedirect.com/science/article/pii/S2211124720301534
http://www.sciencedirect.com/science/article/pii/S2211124720301534
Autor:
Christine Brown, Lawrence M. Schwartz, Travis Thomson, Zhiping Weng, William E. Theurkauf, Junko Tsuji, Subhanita Ghosh
PiWi-interacting RNAs (piRNAs) are small single-stranded RNAs that can repress transposon expression via epigenetic silencing and transcript degradation. They have been identified predominantly in the ovary and testis, where they serve essential role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::484404b3a78611b433d2913271496057
https://doi.org/10.1101/2021.03.02.433533
https://doi.org/10.1101/2021.03.02.433533
Publikováno v:
Dev Cell
piRNAs guide Piwi/Panoramix-dependent H3K9me3 chromatin modification and transposon silencing during Drosophila germline development. The THO RNA export complex is composed of Hpr1, Tho2, and Thoc5–7. Null thoc7 mutations, which displace Thoc5 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542efec2e14493a2dbaaa8db0db4cf83
https://pubmed.ncbi.nlm.nih.gov/34547226
https://pubmed.ncbi.nlm.nih.gov/34547226