Zobrazeno 1 - 10
of 21
pro vyhledávání: '"William E Matchett"'
Autor:
Jessica K Fiege, Joshua M Thiede, Hezkiel Arya Nanda, William E Matchett, Patrick J Moore, Noe Rico Montanari, Beth K Thielen, Jerry Daniel, Emma Stanley, Ryan C Hunter, Vineet D Menachery, Steven S Shen, Tyler D Bold, Ryan A Langlois
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009292 (2021)
The human airway epithelium is the initial site of SARS-CoV-2 infection. We used flow cytometry and single cell RNA-sequencing to understand how the heterogeneity of this diverse cell population contributes to elements of viral tropism and pathogenes
Externí odkaz:
https://doaj.org/article/68102c0c4b2f4a7984aa55fb2d7b97a4
Autor:
Meghan M Painter, James H Morrison, Laurie J Zoecklein, Tommy A Rinkoski, Jens O Watzlawik, Louisa M Papke, Arthur E Warrington, Allan J Bieber, William E Matchett, Kari L Turkowski, Eric M Poeschla, Moses Rodriguez
Publikováno v:
PLoS Pathogens, Vol 11, Iss 12, p e1005311 (2015)
For many emerging and re-emerging infectious diseases, definitive solutions via sterilizing adaptive immunity may require years or decades to develop, if they are even possible. The innate immune system offers alternative mechanisms that do not requi
Externí odkaz:
https://doaj.org/article/a7744516c8e147598d583085c9739909
Autor:
William E. Matchett, Stephanie Anguiano-Zarate, Goda Baddage Rakitha Malewana, Haley Mudrick, Melissa Weldy, Clayton Evert, Alexander Khoruts, Michael Sadowsky, Michael A. Barry
Publikováno v:
Vaccines, Vol 8, Iss 3, p 470 (2020)
Clostridium difficile causes nearly 500,000 infections and nearly 30,000 deaths each year in the U.S., which is estimated to cost $4.8 billion. C. difficile infection (CDI) arises from bacteria colonizing the large intestine and releasing two toxins,
Externí odkaz:
https://doaj.org/article/f00be2bc33194d98a768b053726c0cbb
Autor:
William E. Matchett, Goda Baddage Rakitha Malewana, Haley Mudrick, Michael J. Medlyn, Michael A. Barry
Publikováno v:
Vaccines, Vol 8, Iss 1, p 64 (2020)
Most infections occur at mucosal surfaces. Providing a barrier of protection at these surfaces may be a useful strategy to combat the earliest events in infection when there are relatively few pathogens to address. The majority of vaccines are delive
Externí odkaz:
https://doaj.org/article/b2d0e0b47e7f4637b2557262bc7bd90f
Autor:
Kathryn A. Pape, Thamotharampillai Dileepan, William E. Matchett, Charles Ellwood, Samuel Stresemann, Amanda J. Kabage, Daria Kozysa, Clayton Evert, Michael Matson, Sharon Lopez, Peter D. Krueger, Carolyn T. Graiziger, Byron P. Vaughn, Eugenia Shmidt, Joshua Rhein, Timothy W. Schacker, Tyler D. Bold, Ryan A. Langlois, Alexander Khoruts, Marc K. Jenkins
Publikováno v:
JCI Insight. 7
Immunosuppressed patients with inflammatory bowel disease (IBD) generate lower amounts of SARS-CoV-2 spike antibodies after mRNA vaccination than healthy controls. We assessed SARS-CoV-2 spike S1 receptor binding domain-specific (S1-RBD-specific) B l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fab41efde93448bfbcac6a9146375e
https://doi.org/10.1172/jci.insight.159618
https://doi.org/10.1172/jci.insight.159618
Autor:
Obinna C. Ubah, Eric W. Lake, Gihan S. Gunaratne, Joseph P. Gallant, Marie Fernie, Austin J. Robertson, Jonathan S. Marchant, Tyler D. Bold, Ryan A. Langlois, William E. Matchett, Joshua M. Thiede, Ke Shi, Lulu Yin, Nicholas H. Moeller, Surajit Banerjee, Laura Ferguson, Marina Kovaleva, Andrew J. Porter, Hideki Aihara, Aaron M. LeBeau, Caroline J. Barelle
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Single-domain Variable New Antigen Receptors (VNARs) from the immune system of sharks are the smallest naturally occurring binding domains found in nature. Possessing flexible paratopes that can recognize protein motifs inaccessible to classical anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e3e42cbfec3e27a12039bf347422d2
https://pubmed.ncbi.nlm.nih.gov/34916516
https://pubmed.ncbi.nlm.nih.gov/34916516
Autor:
J. Michael Stolley, Peter J. Southern, Siddheshvar Bhela, Thamotharampillai Dileepan, Maxim C.-J. Cheeran, Vineet Joag, Marc K. Jenkins, Sathi Wijeyesinghe, Joshua M. Thiede, Luca Schifanella, Jules A. Sangala, Clare F. Quarnstrom, Geoffrey T. Hart, Stephen D O'Flanagan, Sung-Wook Hong, Venkatramana D. Krishna, William E. Matchett, Noah V. Gavil, David Masopust, Sailaja Gangadhara, Tyler D. Bold, Eyob Weyu, Ryan A. Langlois, Vaiva Vezys, Rama Rao Amara, Andrew G. Soerens
Publikováno v:
J Immunol
The magnitude of SARS-CoV-2–specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control. Whereas many COVID-19 vaccines focus on establishing humoral immunity to viral spike protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dea03208cbb13c98035ec2035630766
https://pubmed.ncbi.nlm.nih.gov/33441437
https://pubmed.ncbi.nlm.nih.gov/33441437
Autor:
Tyler D. Bold, Jessica K. Fiege, Ryan A. Langlois, Thomas J. Gniadek, Abigail R Gress, William E. Matchett, Marc K. Jenkins, Kathryn A. Pape, Joshua M. Thiede, Vineet D. Menachery
Publikováno v:
Transfusion
bioRxiv
bioRxiv
BACKGROUND: The transfer of passive immunity with convalescent plasma is a promising strategy for treatment and prevention of COVID-19, but donors with a history of nonsevere disease are serologically heterogenous. The relationship between SARS-Cov-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503109af3ab0e302b1e042bde4e03429
https://europepmc.org/articles/PMC7995753/
https://europepmc.org/articles/PMC7995753/
Autor:
Clayton Evert, Alexander Khoruts, Goda Baddage Rakitha Malewana, Michael J. Sadowsky, Michael A. Barry, Stephanie S. Anguiano-Zarate, William E. Matchett, Melissa Weldy, Haley Mudrick
Publikováno v:
Vaccines
Volume 8
Issue 3
Vaccines, Vol 8, Iss 470, p 470 (2020)
Volume 8
Issue 3
Vaccines, Vol 8, Iss 470, p 470 (2020)
Clostridium difficile causes nearly 500,000 infections and nearly 30,000 deaths each year in the U.S., which is estimated to cost $4.8 billion. C. difficile infection (CDI) arises from bacteria colonizing the large intestine and releasing two toxins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815168baf26801e26024afd3061bc1b0
Autor:
Stephanie S. Anguiano-Zarate, William E. Matchett, Pramod N. Nehete, Jagannadha K. Sastry, Michael A. Barry, Andrea Marzi
Publikováno v:
The Journal of Infectious Diseases. 218:1883-1889
Recent West African Ebola virus (EBOV) epidemics have led to testing different anti-EBOV vaccines, including a replication-defective adenovirus (RD-Ad) vector (ChAd3-EBOV) and an infectious, replication-competent recombinant vesicular stomatitis viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::098504e15da9ff2705dc09446e29b2ee
https://doi.org/10.1093/infdis/jiy411
https://doi.org/10.1093/infdis/jiy411