Zobrazeno 1 - 10
of 31
pro vyhledávání: '"William E Diehl"'
Autor:
Dibyendu Kumar Das, Uriel Bulow, William E Diehl, Natasha D Durham, Fernando Senjobe, Kartik Chandran, Jeremy Luban, James B Munro
Publikováno v:
PLoS Biology, Vol 18, Iss 2, p e3000626 (2020)
The Ebola virus (EBOV) envelope glycoprotein (GP) is a membrane fusion machine required for virus entry into cells. Following endocytosis of EBOV, the GP1 domain is cleaved by cellular cathepsins in acidic endosomes, removing the glycan cap and expos
Externí odkaz:
https://doaj.org/article/05e0e4e295874e04b946f426f10d4105
Publikováno v:
eLife, Vol 5 (2016)
Mammalian genomes typically contain hundreds of thousands of endogenous retroviruses (ERVs), derived from ancient retroviral infections. Using this molecular 'fossil' record, we reconstructed the natural history of a specific retrovirus lineage (ERV-
Externí odkaz:
https://doaj.org/article/26c461bc37ac4ae081e659a881dfe516
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58532 (2013)
All genes in the TRIM6/TRIM34/TRIM5/TRIM22 locus are type I interferon inducible, with TRIM5 and TRIM22 possessing antiviral properties. Evolutionary studies involving the TRIM6/34/5/22 locus have predominantly focused on the coding sequence of the g
Externí odkaz:
https://doaj.org/article/369a16877e0544f98c6f8c92d4397215
Autor:
Laura Odongo, Kaneil K. Zadrozny, William E. Diehl, Jeremy Luban, Judith M. White, Barbie K. Ganser-Pornillos, Lukas K. Tamm, Owen Pornillos
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 79:45-50
Niemann–Pick C1 protein (NPC1) is a membrane protein that primarily resides in late endosomes and lysosomes, and plays an important role in cholesterol homeostasis in the cell. The second luminal domain of NPC1 (NPC1-C) serves as the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093c95ddf74108bee21047c87723fb60
https://doi.org/10.1107/s2053230x23000705
https://doi.org/10.1107/s2053230x23000705
Autor:
William E. Diehl, Mehmet H. Guney, Teresa Vanzo, Pyae P. Kyawe, Judith M. White, Massimo Pizzato, Jeremy Luban
Publikováno v:
Viruses, Vol 13, Iss 7, p 1279 (2021)
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells. Three structurally unrelated proteins encoded by diverse retroviruses, human immunodeficiency virus
Externí odkaz:
https://doaj.org/article/52c34191bdc2468daadae2dbe2a528d4
Autor:
Massimo Pizzato, Pyae Phyo Kyawe, Mehmet Hakan Guney, Jeremy Luban, Judith M. White, Teresa Vanzo, William E. Diehl
Publikováno v:
Viruses
Volume 13
Issue 7
Viruses, Vol 13, Iss 1279, p 1279 (2021)
Volume 13
Issue 7
Viruses, Vol 13, Iss 1279, p 1279 (2021)
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells. Three structurally unrelated proteins encoded by diverse retroviruses, human immunodeficiency virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca32493edc96ac9fe6fa8a52b4835c9a
Autor:
Kristen E. Pascal, William E. Diehl, Christos A. Kyratsous, Pardis C. Sabeti, Christopher Tomkins-Tinch, Natalya Dudkina, Stephen F. Schaffner, Claudia Carbone, Leonid Yurkovetskiy, Abhi Barve, Yetao Wang, Ann Dauphin, Kristen Veinotte, James B. Munro, Jacob E. Lemieux, Ashique Rafique, Alina Baum, Jeremy Luban, Xue Wang, Kuang Shen, Shawn B. Egri, Thomas Nyalile
SUMMARYThe SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide in a matter of months. Here we show that D614G was more infectious than the ancestral form on human lung cells, colon cells, and cells rendered permissive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1507110476de01df47f1c0319149cbbe
https://doi.org/10.1101/2020.07.04.187757
https://doi.org/10.1101/2020.07.04.187757
Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines
Autor:
Leonid Yurkovetskiy, Kyusik Kim, Jeremy Luban, Ann Dauphin, William E. Diehl, Anetta Nowosielska, Sean M. McCauley
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications
HIV-1-infected people who take drugs that suppress viremia to undetectable levels are protected from developing AIDS. Nonetheless, HIV-1 establishes proviruses in long-lived CD4+ memory T cells, and perhaps other cell types, that preclude elimination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaf738b24f7b8531586e36063a793a1
http://link.springer.com/article/10.1038/s41467-018-07753-2
http://link.springer.com/article/10.1038/s41467-018-07753-2
Autor:
James B. Munro, Kristen E. Pascal, Christopher Tomkins-Tinch, William E. Diehl, Shawn B. Egri, Jeremy Luban, Ann Dauphin, Thomas Nyalile, Christos A. Kyratsous, Ashique Rafique, Yetao Wang, Kristen Veinotte, Alina Baum, Pardis C. Sabeti, Stephen F. Schaffner, Jacob E. Lemieux, Abhi Barve, Natalya Dudkina, Leonid Yurkovetskiy, Claudia Carbone, Xue Wang, Kuang Shen
Publikováno v:
Cell
The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide, reaching near fixation in a matter of months. Here we show that D614G was more infectious than the ancestral form on human lung cells, colon cells, and on cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286e96378ef62a9d6fcb9cbd5888b8cc
https://doi.org/10.2139/ssrn.3657338
https://doi.org/10.2139/ssrn.3657338
Autor:
Jeremy Luban, Massimo Pizzato, Pyae Phyo Kyawe, Judith M. White, Mehmet Hakan Guney, William E. Diehl
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells. Three accessory proteins encoded by diverse retroviruses, HIV-1 Nef, EIAV S2, and MLV Glycogag, eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b9a390990fa84c064efc5aad79a278