Zobrazeno 1 - 10
of 159
pro vyhledávání: '"William E Ackerman"'
Autor:
Heather M Brockway, Suhas G Kallapur, Irina A Buhimschi, Catalin S Buhimschi, William E Ackerman, Louis J Muglia, Helen N Jones
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225062 (2019)
Preterm birth (PTB) is leading contributor to infant death in the United States and globally, yet the underlying mechanistic causes are not well understood. Histopathological studies of preterm birth suggest advanced villous maturity may have a role
Externí odkaz:
https://doaj.org/article/9b77a31c98924d2b99e2a126fc5488b3
Autor:
Leonithas I Volakis, Ruth Li, William E Ackerman, Cosmin Mihai, Meagan Bechel, Taryn L Summerfield, Christopher S Ahn, Heather M Powell, Rachel Zielinski, Thomas J Rosol, Samir N Ghadiali, Douglas A Kniss
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86110 (2014)
Cell migration plays a central role in the invasion and metastasis of tumors. As cells leave the primary tumor, they undergo an epithelial to mesenchymal transition (EMT) and migrate as single cells. Epithelial tumor cells may also migrate in a highl
Externí odkaz:
https://doaj.org/article/3d2c61869897490db838cece07bd8fd7
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81003 (2013)
The syncytiotrophoblast of the human placenta is an epithelial barrier that interacts with maternal blood and is a key for the transfer of nutrients and other solutes to the developing fetus. The syncytiotrophoblast is a true syncytium and fusion of
Externí odkaz:
https://doaj.org/article/170b55c621d44f4d86fa3084c1e4ccd6
Autor:
Ruth Li, William E Ackerman, Cosmin Mihai, Leonithas I Volakis, Samir Ghadiali, Douglas A Kniss
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39766 (2012)
Myoferlin (MYOF) is a mammalian ferlin protein with homology to ancestral Fer-1, a nematode protein that regulates spermatic membrane fusion, which underlies the amoeboid-like movements of its sperm. Studies in muscle and endothelial cells have repor
Externí odkaz:
https://doaj.org/article/03366001aa0f4de9aaf366f0dbc14e10
Autor:
Ruth Li, William E Ackerman, Taryn L Summerfield, Lianbo Yu, Parul Gulati, Jie Zhang, Kun Huang, Roberto Romero, Douglas A Kniss
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20560 (2011)
A majority of the studies examining the molecular regulation of human labor have been conducted using single gene approaches. While the technology to produce multi-dimensional datasets is readily available, the means for facile analysis of such data
Externí odkaz:
https://doaj.org/article/9af8bedbe9ce42868fd4b0282a407624
Autor:
William E. Ackerman, Catalin S. Buhimschi, Thomas L. Brown, Guomao Zhao, Taryn L. Summerfield, Irina A. Buhimschi
Background: Placental disorders contribute to pregnancy complications, including preeclampsia and fetal growth restriction (FGR), but debate regarding their specific pathobiology persists. Our objective was to apply transcriptomics with weighted gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b80c09abeb1a0426c0eee6fae9a9070
https://doi.org/10.1101/2023.03.08.23286998
https://doi.org/10.1101/2023.03.08.23286998
Autor:
Rosa S. Valtanen, Catalin S. Buhimschi, Mert O. Bahtiyar, Guomao Zhao, Hongwu Jing, William E. Ackerman, Charles G. Glabe, Irina A. Buhimschi
Publikováno v:
Pregnancy Hypertens
Prior research has shown that urine of women with preeclampsia (PE) contains amyloid-like aggregates that are congophilic (exhibit affinity for the amyloidophilic dye Congo red) and immunoreactive with A11, a polyclonal serum against prefibrillar β-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee80cbea859815a0b526efe613860a7e
Autor:
William E. Ackerman, Guomao Zhao, Irina A. Buhimschi, Catalin S. Buhimschi, Ali Snedden, Taryn Summerfield
Clinical phenotyping of term and preterm labor is imprecise, and disagreement persists on categorization relative to underlying pathobiology, which remains poorly understood. We performed RNA sequencing (RNA-seq) of 31 specimens of human uterine myom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0376c72eb67e894c72fc8bace25ae114
Autor:
Parker R. Murphy, Leif D. Nelin, Bridget A. Bowman, Yusen Liu, Xiantao Wang, Abel J. Batty, Jian Zhang, Charles J. Cash, William E. Ackerman, Timothy J. Barley, Markus Hafner, Sean G. Kirk
Publikováno v:
J Immunol
We have previously shown that Mkp-1–deficient mice produce elevated TNF-α, IL-6, and IL-10 following systemic Escherichia coli infection, and they exhibited increased mortality, elevated bacterial burden, and profound metabolic alterations. To und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503f65dc9aad2d8f543e5b96bc1333d4
Autor:
Yara El Helou, Guomao Zhao, Catalin S. Buhimschi, Hongwu Jing, William E. Ackerman, Irina A. Buhimschi
Publikováno v:
Placenta
We conducted a protein-protein interaction (PPI) network study searching for proteins relevant to pregnancy-associated COVID-19 in pregnancy complicated with severe preeclampsia (sPE) and intra-amniotic infection and/or inflammation (Triple-I). PPI n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1178d2940cceec237bdfc031d4bc16