Zobrazeno 1 - 10
of 272
pro vyhledávání: '"William Deakin"'
Autor:
Tomas Hökfelt, Swapnali Barde, Zhi-Qing David Xu, Eugenia Kuteeva, Joelle Rüegg, Erwan Le Maitre, Mårten Risling, Jan Kehr, Robert Ihnatko, Elvar Theodorsson, Miklos Palkovits, William Deakin, Gyorgy Bagdy, Gabriella Juhasz, H. Josée Prud’homme, Naguib Mechawar, Rochellys Diaz-Heijtz, Sven Ove Ögren
Publikováno v:
Frontiers in Neural Circuits, Vol 12 (2018)
Neuropeptides are auxiliary messenger molecules that always co-exist in nerve cells with one or more small molecule (classic) neurotransmitters. Neuropeptides act both as transmitters and trophic factors, and play a role particularly when the nervous
Externí odkaz:
https://doaj.org/article/0a86a9988405408a9a1019d2d04c8eef
Autor:
Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Berta Erdelyi-Hamza, Peter Petschner, Beata Sperlagh, Ian M. Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Emotional stress is a leading risk factor in the development of neuropsychiatric disorders possibly via immune activation. P2X7 receptors promote neuroinflammation, and research suggests a relationship between chromosome region 12q2431, in w
Externí odkaz:
https://doaj.org/article/81986f79dbbe4dbd83f4ed8d9fedeb10
Autor:
Cynthia H. Y. Fu, Guray Erus, Yong Fan, Mathilde Antoniades, Danilo Arnone, Stephen R. Arnott, Taolin Chen, Ki Sueng Choi, Cherise Chin Fatt, Benicio N. Frey, Vibe G. Frokjaer, Melanie Ganz, Jose Garcia, Beata R. Godlewska, Stefanie Hassel, Keith Ho, Andrew M. McIntosh, Kun Qin, Susan Rotzinger, Matthew D. Sacchet, Jonathan Savitz, Haochang Shou, Ashish Singh, Aleks Stolicyn, Irina Strigo, Stephen C. Strother, Duygu Tosun, Teresa A. Victor, Dongtao Wei, Toby Wise, Rachel D. Woodham, Roland Zahn, Ian M. Anderson, J. F. William Deakin, Boadie W. Dunlop, Rebecca Elliott, Qiyong Gong, Ian H. Gotlib, Catherine J. Harmer, Sidney H. Kennedy, Gitte M. Knudsen, Helen S. Mayberg, Martin P. Paulus, Jiang Qiu, Madhukar H. Trivedi, Heather C. Whalley, Chao-Gan Yan, Allan H. Young, Christos Davatzikos
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic criteria are currently symptom-based, MDD is conceptualized as a disorder rathe
Externí odkaz:
https://doaj.org/article/c4130b307f0648e6a85a0f1b24a7458d
Autor:
Samaneh Nemati, Teddy J. Akiki, Jeremy Roscoe, Yumeng Ju, Christopher L. Averill, Samar Fouda, Arpan Dutta, Shane McKie, John H. Krystal, J.F. William Deakin, Lynnette A. Averill, Chadi G. Abdallah
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: More than six decades have passed since the discovery of monoaminergic antidepressants. Yet, it remains a mystery why these drugs take weeks to months to achieve therapeutic effects, although their monoaminergic actions are present rapidly a
Externí odkaz:
https://doaj.org/article/74c83b13024e4ecdb74244a3fd7bbbed
Publikováno v:
In Biological Psychiatry: Cognitive Neuroscience and Neuroimaging April 2017 2(3):253-262
Autor:
Rebecca B. Price, Nicholas Kissel, Andrew Baumeister, Rebecca Rohac, Mary L. Woody, Elizabeth D. Ballard, Carlos A. Zarate, William Deakin, Chadi G. Abdallah, Adriana Feder, Dennis S. Charney, Michael F. Grunebaum, J. John Mann, Sanjay J. Mathew, Bronagh Gallagher, Declan M. McLoughlin, James W. Murrough, Suresh Muthukumaraswamy, Rebecca McMillan, Rachael Sumner, George Papakostas, Maurizio Fava, Rebecca Hock, Jennifer L. Phillips, Pierre Blier, Paulo Shiroma, Peter Šóš, Tung-Ping Su, Mu-Hong Chen, Mikael Tiger, Johan Lundberg, Samuel T. Wilkinson, Meredith L. Wallace
Publikováno v:
Molecular Psychiatry. 27:5096-5112
Depression is disabling and highly prevalent. Intravenous (IV) ketamine displays rapid-onset antidepressant properties, but little is known regarding which patients are most likely to benefit, limiting personalized prescriptions. We identified random
Childhood Adversity Moderates the Effects of HTR2A Epigenetic Regulatory Polymorphisms on Rumination
Autor:
Nora Eszlari, Peter Petschner, Xenia Gonda, Daniel Baksa, Rebecca Elliott, Ian Muir Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz
Publikováno v:
Frontiers in Psychiatry, Vol 10 (2019)
The serotonin system has been suggested to moderate the association between childhood maltreatment and rumination, with the latter in its turn reported to be a mediator in the depressogenic effect of childhood maltreatment. Therefore, we investigated
Externí odkaz:
https://doaj.org/article/9788db09efc2491f96e8c6a558b41f16
Autor:
Mathilde Antoniades, Cynthia Fu, Guray Erus, Jose Garcia, Yong Fan, Danilo Arnone, Stephen Arnott, Taolin Chen, Ki Sueng Choi, Cherise Chin Fatt, Benicio Frey, Vibe Frokjaer, Melanie Ganz, Beata Godlewska, Stefanie Hassel, Keith Ho, Andrew McIntosh, Kun Qin, Susan Rotzinger, Matthew Sacchet, Jonathan Savitz, Haochang Shou, Ashish Singh, Aleks Stolicyn, Irina Strigo, Stephen Strother, Duygu Tosun, Teresa Victor, Dongtao Wei, Toby Wise, Roland Zahn, Ian Anderson, J.F. William Deakin, Boadie Dunlop, Rebecca Elliott, Qiyong Gong, Ian Gotlib, Catherine Harmer, Sidney Kennedy, Gitte Knudsen, Helen Mayberg, Martin Paulus, Jiang Qiu, Madhukar Trivedi, Heather Whalley, Chao-Gan Yan, Allan Young, Christos Davatzikos
Importance: Major depressive disorder (MDD) is a heterogeneous clinical syndrome with widespread subtle neuroanatomical correlates. Identifying neuroimaging-based biomarkers might aid in defining the disease-related dimensions that characterize MDD a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fadb8e77dfe1c25d91411a6d65dcac6
https://doi.org/10.21203/rs.3.rs-2289671/v1
https://doi.org/10.21203/rs.3.rs-2289671/v1
Autor:
Chadi G. Abdallah, Arpan Dutta, Christopher L. Averill, Shane McKie, Teddy J. Akiki, Lynnette A. Averill, J. F. William Deakin
Publikováno v:
Chronic Stress, Vol 2 (2018)
Background Identifying the neural correlates of ketamine treatment may facilitate and expedite the development of novel, robust, and safe rapid-acting antidepressants. Prefrontal cortex (PFC) global brain connectivity with global signal regression (G
Externí odkaz:
https://doaj.org/article/98c305e59c044b009d9d8d69a5dc19da
Autor:
Florent Meyniel, Guy M Goodwin, JF William Deakin, Corinna Klinge, Christine MacFadyen, Holly Milligan, Emma Mullings, Mathias Pessiglione, Raphaël Gaillard
Publikováno v:
eLife, Vol 5 (2016)
Serotonin is implicated in many aspects of behavioral regulation. Theoretical attempts to unify the multiple roles assigned to serotonin proposed that it regulates the impact of costs, such as delay or punishment, on action selection. Here, we show t
Externí odkaz:
https://doaj.org/article/eb48ae8df5ec41249056c065a7edef97