Zobrazeno 1 - 10
of 141
pro vyhledávání: '"William D. Snider"'
Autor:
Jing Zhou, An-Chi Tien, John A. Alberta, Scott B. Ficarro, Amelie Griveau, Yu Sun, Janhavee S. Deshpande, Joseph D. Card, Meghan Morgan-Smith, Wojciech Michowski, Rintaro Hashizume, C. David James, Keith L. Ligon, William D. Snider, Peter Sicinski, Jarrod A. Marto, David H. Rowitch, Charles D. Stiles
Publikováno v:
Cell Reports, Vol 18, Iss 13, Pp 3167-3177 (2017)
During development of the vertebrate CNS, the basic helix-loop-helix (bHLH) transcription factor Olig2 sustains replication competence of progenitor cells that give rise to neurons and oligodendrocytes. A pathological counterpart of this developmenta
Externí odkaz:
https://doaj.org/article/7fb9e82920cf40d1898b5c51de91b9b8
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 165-178 (2016)
In cold-blooded vertebrates such as zebrafish, Müller glial cells (MGs) readily proliferate to replenish lost retinal neurons. In mammals, however, MGs lack regenerative capability as they do not spontaneously re-enter the cell cycle unless the reti
Externí odkaz:
https://doaj.org/article/72342b69bcca4ff58c60a6b55d45b519
Publikováno v:
Neurobiology of Disease, Vol 1, Iss 3, Pp 121-129 (1994)
Studies on the pathogenesis of human motor neurone disease have suffered from the absence of models of motor neurone degeneration in adult animals. Normally in adult rodents, transection of motor neurone axons results in only a modest degree of neuro
Externí odkaz:
https://doaj.org/article/194f971f726a44a69a75576789fc2223
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 4 (2011)
Glycogen synthase kinase 3 (GSK3) is emerging as a key regulator of several aspects of neuronal morphogenesis including neuronal polarization, axon growth and axon branching. Multiple signaling pathways have been identified that control neuronal pola
Externí odkaz:
https://doaj.org/article/49e2bf6fc0724cefa504f574d17d2553
Autor:
William D. Snider
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 4, Pp 207- (1998)
Externí odkaz:
https://doaj.org/article/0d045f1299fa4ccb980b16ef153eccc3
Autor:
William D. Snider
Publikováno v:
Neurobiology of Disease, Vol 4, Iss 3, Pp 311- (1997)
Externí odkaz:
https://doaj.org/article/ff40a2ea3cd7436f9d70d205998bf9a2
Publikováno v:
eLife, Vol 5 (2016)
Axons fail to regenerate after central nervous system (CNS) injury. Modulation of the PTEN/mTORC1 pathway in retinal ganglion cells (RGCs) promotes axon regeneration after optic nerve injury. Here, we report that AKT activation, downstream of Pten de
Externí odkaz:
https://doaj.org/article/20e0f24a7dee4088b9688e421ebe3f82
Autor:
Lei Xing, Rylan S Larsen, George Reed Bjorklund, Xiaoyan Li, Yaohong Wu, Benjamin D Philpot, William D Snider, Jason M Newbern
Publikováno v:
eLife, Vol 5 (2016)
Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway causes pathology in a family of neurodevelopmental disorders known as 'RASopathies' and is implicated in autism pathogenesis. Here, we have determined the functions of ERK/MAPK signaling i
Externí odkaz:
https://doaj.org/article/3d381bd76ab04494a1d0fdf55415926c
Publikováno v:
eLife, Vol 3 (2014)
GSK-3 is an essential mediator of several signaling pathways that regulate cortical development. We therefore created conditional mouse mutants lacking both GSK-3α and GSK-3β in newly born cortical excitatory neurons. Gsk3-deleted neurons expressin
Externí odkaz:
https://doaj.org/article/9b32a7dbd9774aa3be5ff44a6d037619
Autor:
Oleh Krupa, Giulia Fragola, Ellie Hadden-Ford, Jessica T. Mory, Tianyi Liu, Zachary Humphrey, Benjamin W. Rees, Ashok Krishnamurthy, William D. Snider, Mark J. Zylka, Guorong Wu, Lei Xing, Jason L. Stein
Tissue clearing methods allow every cell in the mouse brain to be imaged without physical sectioning. However, the computational tools currently available for cell quantification in cleared tissue images have been limited to counting sparse cell popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981501f55d5f74537aba8be7bc5ba555
https://doi.org/10.1101/2020.09.11.293399
https://doi.org/10.1101/2020.09.11.293399
