Zobrazeno 1 - 10
of 123
pro vyhledávání: '"William D. Picking"'
Autor:
Debaki R. Howlader, Rahul Shubhra Mandal, Ti Lu, Suhrid Maiti, Zackary K. Dietz, Sayan Das, Sean K. Whittier, Aaron C. Nagel, Satabdi Biswas, David J. Varisco, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pseudomonas aeruginosa (Pa) is an opportunistic bacterial pathogen responsible for severe hospital acquired infections in immunocompromised and elderly individuals. Emergence of increasingly drug resistant strains and the absence of a broad-spectrum
Externí odkaz:
https://doaj.org/article/045977411a494c21b6ddb2526b664939
Autor:
Ti Lu, Murugesan Raju, Debaki R. Howlader, Zackary K. Dietz, Sean K. Whittier, David J. Varisco, Robert K. Ernst, Lyndon M. Coghill, William D. Picking, Wendy L. Picking
Publikováno v:
Vaccines, Vol 12, Iss 6, p 618 (2024)
Shigella spp. are responsible for bacillary dysentery or shigellosis transmitted via the fecal–oral route, causing significant morbidity and mortality, especially among vulnerable populations. There are currently no licensed Shigella vaccines. Shig
Externí odkaz:
https://doaj.org/article/c3f8050c393a4aa7b5ff75c873148e6a
Autor:
Ti Lu, Debaki R. Howlader, Sayan Das, Zackary K. Dietz, Aaron C. Nagel, Sean K. Whittier, William D. Picking, Wendy L. Picking
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Shigellosis (bacillary dysentery) is a severe diarrheal disease caused by members of the genus Shigella, which results in 90 million cases annually around the world. The Shigella type III secretion system (T3SS) is a specialized secretion sy
Externí odkaz:
https://doaj.org/article/2675dedfb313405db1995eb860661797
Autor:
Debaki R. Howlader, Sayan Das, Ti Lu, Rahul Shubhra Mandal, Gang Hu, David J. Varisco, Zackary K. Dietz, Siva Sai Kumar Ratnakaram, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract The opportunistic pathogen Pseudomonas aeruginosa (Pa) causes severe nosocomial infections, especially in immunocompromised individuals and the elderly. Increasing drug resistance, the absence of a licensed vaccine and increased hospitalizat
Externí odkaz:
https://doaj.org/article/5bfaa7830aeb4108a21734bbcc9aa1d3
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4329 (2024)
Shigellosis is a severe gastrointestinal disease that annually affects approximately 270 million individuals globally. It has particularly high morbidity and mortality in low-income regions; however, it is not confined to these regions and occurs in
Externí odkaz:
https://doaj.org/article/717daf53e69b41eb8b3e91553ffd493f
Autor:
Saathvik Kannan, Samuel W. Gillespie, Wendy L. Picking, William D. Picking, Christian L. Lorson, Kamal Singh
Publikováno v:
Biology, Vol 13, Iss 4, p 204 (2024)
DNA polymerases replicate cellular genomes and/or participate in the maintenance of genome integrity. DNA polymerases sharing high sequence homology with E. coli DNA polymerase I (pol I) have been grouped in Family A. Pol I participates in Okazaki fr
Externí odkaz:
https://doaj.org/article/b17a0a7821bc4cbeb25df244463d955b
Autor:
Ti Lu, Sayan Das, Debaki R. Howlader, Akshay Jain, Gang Hu, Zackary K. Dietz, Qi Zheng, Siva Sai Kumar Ratnakaram, Sean K. Whittier, David J. Varisco, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Shigellosis (bacillary dysentery) is a severe gastrointestinal infection with a global incidence of 90 million cases annually. Despite the severity of this disease, there is currently no licensed vaccine against shigellosis. Shigella’s primary viru
Externí odkaz:
https://doaj.org/article/96e7e423772c4f73a7467c187bacfbb4
Autor:
Gang Hu, David J. Varisco, Sayan Das, C. Russell Middaugh, Francesca Gardner, Robert K. Ernst, Wendy L. Picking, William D. Picking
Publikováno v:
Heliyon, Vol 9, Iss 7, Pp e18119- (2023)
Toll-like receptor (TLR) agonists are recognized as potential immune-enhancing adjuvants and are included in several licensed vaccines. Monophosphoryl lipid A (MPL®, GlaxoSmithKline) is one such TLR4 agonist that has been approved for use in human v
Externí odkaz:
https://doaj.org/article/af462990fe1f49968dbe51a4fba38255
Autor:
Sayan Das, Debaki R. Howlader, Ti Lu, Sean K. Whittier, Gang Hu, Simran Sharma, Zackary K. Dietz, Siva S. K. Ratnakaram, David J. Varisco, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Salmonella enterica, a Gram-negative pathogen, has over 2500 serovars that infect a wide range of hosts. In humans, S. enterica causes typhoid or gastroenteritis and is a major public health concern. In this study, SseB (the tip protein of the Salmon
Externí odkaz:
https://doaj.org/article/66769d63d0b2439c90ca64d0abcce2b8
Autor:
Debaki R. Howlader, Sayan Das, Ti Lu, Gang Hu, David J. Varisco, Zackary K. Dietz, Sierra P. Walton, Siva Sai Kumar Ratnakaram, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pseudomonas aeruginosa is an opportunistic pathogen responsible for a wide range of infections in humans. In addition to its innate antibiotic resistance, P. aeruginosa is very effective in acquiring resistance resulting in the emergence of multi-dru
Externí odkaz:
https://doaj.org/article/66c6b6c331804934846b2aa4b9efbfe7