Zobrazeno 1 - 10
of 34
pro vyhledávání: '"William D. Matthew"'
Publikováno v:
Experimental Neurology. 169:13-22
Apolipoprotein E (apoE) is well characterized as a plasma lipoprotein involved in lipid and cholesterol metabolism. Recent studies implicating apoE in Alzheimer's disease and successful recovery from neurological injury have stimulated much interest
Publikováno v:
Journal of Neuroimmunology. 114:107-113
Apolipoprotein E (apoE) is a 299 amino acid protein that is associated with risk of developing Alzheimer’s Disease (AD) and outcome after acute brain injury. To investigate the possibility that apoE modulates glial activation we studied the effect
Publikováno v:
Journal of Neuroimmunology. 76:70-74
Apolipoprotein E (apoE) is a 299 amino acid protein with multiple biological functions. Initially described in the context of cholesterol metabolism, apoE also has immunomodulatory properties and recent evidence has implicated a role for apoE in neur
Autor:
Marcia J. Riggott, William D. Matthew
Publikováno v:
Experimental Neurology. 145:278-287
Exogenously added gangliosides enhance sprouting, neurite outgrowth, and other neuronal activities; this effect may be initiated when a ganglioside binds to a membrane protein or when a ganglioside intercalates into the plasma membrane. To test wheth
Autor:
Marcia J. Riggott, William D. Matthew
Publikováno v:
Glycobiology. 6:581-589
Ganglioside stimulated neurite outgrowth may be due to ganglioside binding to membrane proteins or to intercalation into the membrane. To test that ganglioside binding proteins could be found on neuronal surfaces, anti-idiotypic ganglioside monoclona
Autor:
Karl H. Weisgraber, Jeffery M. Vance, Ann M. Saunders, Warren J. Strittmatter, James R. Burke, Burton L. Scott, A. D. Roses, V. S. DeSerrano, William D. Matthew, David Huang
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 61:597-605
Autor:
James L. Salzer, William D. Matthew, D. Lawson, Willem Hendrik Gispen, Peter Canoll, I. J. Isaacs, D. I. Gwynne, L. E. Chen, M. A. Marchionni, W. F. Holt, Nagesh K. Mahanthappa, R. Reynolds, D. Meun, Cedric S. Raine, Eva S. Anton, Frank P.T. Hamers, C. J. Hoban, C. J. Kirk, B. Cannella, C. Chen, F. Wason
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 61:459-472
Publikováno v:
Developmental Biology. 164:133-146
Monoclonal antibodies that block the cellular function(s) of specific antigens can provide valuable probes for in vitro and in vivo bioassays. With the goal of understanding the molecular basis of neuron-Schwann cell interactions during development a
Publikováno v:
Proceedings of the National Academy of Sciences. 91:2795-2799
Migrating Schwann cells in developing or regenerating peripheral nerves are known to express dramatically increased levels of nerve growth factor (NGF) and the low-affinity NGF receptor (LNGFR). Schwann cells do not express detectable pp140trk, the N
Publikováno v:
Experimental neurology. 153(1)
Apolipoprotein E (apoE), a plasma lipoprotein involved in lipid metabolism, is also proposed to have important functions within the central and peripheral nervous systems. To investigate the function of apoE in the peripheral nervous system, we exami