Zobrazeno 1 - 10
of 35
pro vyhledávání: '"William D. Kim"'
Publikováno v:
European Journal of Cell Biology, Vol 102, Iss 4, Pp 151361- (2023)
Major facilitator superfamily domain-containing protein 8 (MFSD8) is a transmembrane protein that has been reported to function as a lysosomal chloride channel. In humans, homozygous mutations in MFSD8 cause a late-infantile form of neuronal ceroid l
Externí odkaz:
https://doaj.org/article/5f23394d979c4523995e08666c1666d7
Autor:
Iksung Cho, William D. Kim, Subin Kim, Kyu-Yong Ko, Yeonchan Seong, Dae-Young Kim, Jiwon Seo, Chi Young Shim, Jong-Won Ha, Makoto Mori, Aakriti Gupta, Seng Chan You, Geu-Ru Hong, Harlan M. Krumholz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The management and follow-up of moderate aortic stenosis (AS) lacks consensus as the progression patterns are not well understood. This study aimed to identify the hemodynamic progression of AS, and associated risk factors and outcomes. We i
Externí odkaz:
https://doaj.org/article/11758045f9de4044b23a9409157d1ff6
Autor:
Jinhwan Jo, Min Jae Cha, Hee Jeong Lee, William D. Kim, Jinseob Kim, Kyung Eun Ha, Subin Kim, Chi Young Shim, Geu‐Ru Hong, Jong‐Won Ha, Iksung Cho
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 16 (2023)
Background Real‐world evidence for the selection of gatekeeping studies in patients with suspected coronary syndromes is limited. Methods and Results We identified 27 036 patients who underwent coronary computed tomography angiography (CCTA), singl
Externí odkaz:
https://doaj.org/article/6edcde3062564bc8a48d0b32fff26a15
Autor:
Iksung Cho, William D. Kim, Oh Hyun Lee, Min Jae Cha, Jiwon Seo, Chi Young Shim, Hui-Nam Pak, Boyoung Joung, Geu-Ru Hong, Heidi Gransar, Seung Yong Shin, Jung-Sun Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The complex structure of the left atrial appendage (LAA) brings limitations to the two-dimensional-based LAA occlusion (LAAO) size prediction system using transesophageal echocardiography. The LAA anatomy can be evaluated more precisely usin
Externí odkaz:
https://doaj.org/article/69960b2a884a42faab597cc4d4ac72fb
Autor:
William D. Kim, Robert J. Huber
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Mutations in CLN5 cause a subtype of neuronal ceroid lipofuscinosis (NCL) called CLN5 disease. The NCLs, commonly referred to as Batten disease, are a family of neurodegenerative lysosomal storage diseases that affect all ages and ethnicities globall
Externí odkaz:
https://doaj.org/article/9bd8f8b0a8014bedb7586feb25bbefa4
Autor:
Joo Hyeok Choi, Min Jae Cha, Iksung Cho, William D. Kim, Yera Ha, Hyewon Choi, Sun Hwa Lee, Seng Chan You, Jee Suk Chang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
This study aimed to demonstrate clinical feasibility of deep learning (DL)-based fully automated coronary artery calcium (CAC) scoring software using non-electrocardiogram (ECG)-gated chest computed tomography (CT) from patients with cancer. Overall,
Externí odkaz:
https://doaj.org/article/d47b63c7c4854da78ef6b7da5d00416c
Mfsd8 Modulates Growth and the Early Stages of Multicellular Development in Dictyostelium discoideum
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
MFSD8 is a transmembrane protein that has been reported to transport chloride ions across the lysosomal membrane. Mutations in MFSD8 are associated with a subtype of Batten disease called CLN7 disease. Batten disease encompasses a family of 13 inheri
Externí odkaz:
https://doaj.org/article/343531e063fa490ebf55878366515843
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cullins (CULs) are a core component of cullin-RING E3 ubiquitin ligases (CRLs), which regulate the degradation, function, and subcellular trafficking of proteins. CULs are post-translationally regulated through neddylation, a process that conjugates
Externí odkaz:
https://doaj.org/article/da056d306f5b4dc181b40cd97d05c63c
Autor:
William D. Kim, Morgan L. D. M. Wilson-Smillie, Aruban Thanabalasingam, Stephane Lefrancois, Susan L. Cotman, Robert J. Huber
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The neuronal ceroid lipofuscinoses (NCLs), also referred to as Batten disease, are a family of neurodegenerative diseases that affect all age groups and ethnicities around the globe. At least a dozen NCL subtypes have been identified that are each li
Externí odkaz:
https://doaj.org/article/69177886e3e149318f5e1cda68a724f5
Autor:
William D. Kim, Iksung Cho, Young Doo Kim, Min Jae Cha, Sang-Wook Kim, Young Choi, Seung Yong Shin
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundThe two-dimensional (2D)-based left atrial appendage (LAA) occluder (LAAO) size determination by using transesophageal echocardiography (TEE) is limited by the structural complexity and wide anatomical variation of the LAA.ObjectiveThis stu
Externí odkaz:
https://doaj.org/article/0fd95a4c652e49118cdfadc35e7774bb