Výsledky vyhledávání - "William D. Hoffman"

Visualization of Lipid Droplet Composition by Direct Organelle Mass Spectrometry

Autor: William D. Hoffman, Charlene R. Case, Guido F. Verbeck, Christopher N. James, Nicole R. Ledbetter, Kent D. Chapman, Patrick J. Horn

Publikováno v: Journal of Biological Chemistry. 286:3298-3306

An expanding appreciation for the varied functions of neutral lipids in cellular organisms relies on a more detailed understanding of the mechanisms of lipid production and packaging into cytosolic lipid droplets (LDs). Conventional lipid profiling p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b71f2acbb0f7bff9c4224ba1d64ee7
https://doi.org/10.1074/jbc.m110.186353

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Reduced Argatroban Doses After Coronary Artery Bypass Graft Surgery

Autor: Marcie J. Hursting, David McCollum, William D. Hoffman, Yvonne Czyz

Publikováno v: Annals of Pharmacotherapy. 42:309-316

Background: The Food and Drug Administration–approved argatroban dose for heparin-induced thrombocytopenia (HIT) is 2 μg/kg/min (0.5 μg/kg/min in hepatic impairment), adjusted to achieve activated partial thromboplastin time (aPTT) 1.5–3 times

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c748d2cd6feb55cafbb400fe3ae83a39
https://doi.org/10.1345/aph.1k434

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Randomization in clinical trials of titrated therapies: Unintended consequences of using fixed treatment protocols*

Autor: Steven M. Banks, Peter Q. Eichacker, Anthony F. Suffredini, Peter C. Minneci, William D. Hoffman, Alan N. Schechter, Harvey G. Klein, Robert L. Danner, Xizhong Ciu, Charles Natanson, Katherine J. Deans

Publikováno v: Critical Care Medicine. 35:1509-1516

Objective: Clinical trial designs that randomize patients to fixed treatment regimens may disrupt preexisting relationships between illness severity and level of therapy. The practice misalignments created by such designs may have unintended effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad40736d35edb4b4fb9f126f6fdf52e1
https://doi.org/10.1097/01.ccm.0000266584.40715.a6

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Serial measures of total body oxygen consumption in an awake canine model of septic shock

Autor: William D. Hoffman, Peter Q. Eichacker, Steven Richmond, Robert L. Danner, Steven M. Banks, Yvonne Fitz, Charles Natanson

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 154:68-75

We examined serial changes in total body oxygen consumption (Vo2) in a permanently tracheotomized canine sepsis model. On Day 0, beagles had an Escherichia coli-infected (septic) or sterile (control) clot surgically placed in the peritoneum. During t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6166c22e5d750deca82937130f608db
https://doi.org/10.1164/ajrccm.154.1.8680702

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Emphysematous gastritis

Autor: Samuel Irefin, William D. Hoffman, Norman B. Ratliff, C. Allen Bashour, Allen W. Averbook, Marc J. Popovich, Shahpour Esfandiari

Publikováno v: Surgery. 123:716-718

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f170d73aacfd39e49d2bad6405324a3
https://doi.org/10.1016/s0039-6060(98)70211-9

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Participation of the atrial components of a dual-chamber cardiac pacemaker during ventricular pacing

Autor: William D. Hoffman, Theodore A. Alston

Publikováno v: Journal of cardiothoracic and vascular anesthesia. 19(3)

A 70-year-old man with coronary artery disease, chronic atrial firillation, and cardiomegaly was scheduled for redo coronary bypass urgery. His initial heart rate was 38 beats/min. Because of the bradyardia and the epicardial scarring expected from t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313eb80a7f7a94bd89ef366e6a29c974
https://pubmed.ncbi.nlm.nih.gov/16130070

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