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pro vyhledávání: '"William D. Godfrey"'
Autor:
Janneke E. Jaspers, Jonathan F. Khan, William D. Godfrey, Andrea V. Lopez, Metamia Ciampricotti, Charles M. Rudin, Renier J. Brentjens
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Patients with small cell lung cancer (SCLC) generally have a poor prognosis and a median overall survival of only about 13 months, indicating the urgent need for novel therapies. Delta-like protein 3 (DLL3) has been identified as a tumor-specific cel
Externí odkaz:
https://doaj.org/article/1add364070234a5a9f42731c9c6e16d1
Autor:
Eric L. Smith, Yunxin Chen, Renier J. Brentjens, Carlos Fernández de Larrea, Terence J. Purdon, Hans-Guido Wendel, Vladimir Ponomarev, Andrea V. Lopez, Khong Y. Ng, William D. Godfrey, Mette Staehr
Publikováno v:
Blood Cancer Discovery. 1:146-154
Chimeric antigen receptor (CAR) T-cell therapy for multiple myeloma targeting B-cell maturation antigen (TNFRSF17; BCMA) induces high overall response rates; however, relapse occurs commonly. A reservoir of multiple myeloma cells lacking sufficient B