Zobrazeno 1 - 10
of 73
pro vyhledávání: '"William D. Eldred"'
Autor:
Ellen D. Witkowski, Yuan Gao, Alexander F. Gavsyuk, Ido Maor, Gloria J. DeWalt, William D. Eldred, Adi Mizrahi, Ian G. Davison
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Traumatic brain injury (TBI) affects millions of Americans annually, but effective treatments remain inadequate due to our poor understanding of how injury impacts neural function. Data are particularly limited for mild, closed-skull TBI, which forms
Externí odkaz:
https://doaj.org/article/f3f2cdf7c12e4b45b265352d947eb561
Autor:
William D. Eldred, Gloria J. DeWalt
Publikováno v:
Journal of Comparative Neurology. 525:2955-2967
Injury from blast exposure is becoming a more prevalent cause of death and disability worldwide. The devastating neurological impairments that result from blasts are significant and lifelong. Progress in the development of effective therapies to trea
Autor:
Vasiliki Poulaki, Gloria J. DeWalt, William D. Eldred, Jinghua Chen, Henry J. Kaplan, Marcus D. Gingerich, Joseph F. Rizzo, D. B. Shire, Seong Joon Kim, Sheryl Kane, Ralph J. Jensen
Publikováno v:
Translational Vision Science & Technology
Purpose This work was motivated by the goals of demonstrating methods to fabricate and implant large numbers of penetrating arrays into the retina and the feasibility of extraction. Methods Arrays of inactive, three-dimensional (3D) SU-8 structures w
Autor:
William D. Eldred, Gloria J. DeWalt, Seth Bensussen, Kyle R. Hansen, Bobak Nazer, Xue Han, Ali I. Mohammed, Moona E Abdulkerim, Venkatesh Saligrama, Hua-an Tseng
Publikováno v:
Journal of neurotrauma. 35(13)
Mild traumatic brain injury (mTBI) represents a serious public health concern. Although much is understood about long-term changes in cell signaling and anatomical pathologies associated with mTBI, little is known about acute changes in neuronal func
Autor:
Gloria J, DeWalt, William D, Eldred
Publikováno v:
The Journal of comparative neurology. 525(13)
Injury from blast exposure is becoming a more prevalent cause of death and disability worldwide. The devastating neurological impairments that result from blasts are significant and lifelong. Progress in the development of effective therapies to trea
Publikováno v:
Journal of Neuroscience Research. 87:3134-3142
Nitric oxide (NO) is a major signaling molecule in the retina and CNS, with physiological roles in every cell type in the retina. Previous work shows that neuronal nitric oxide synthase (nNOS) is an important source of NO in the vertebrate retina. Th
Autor:
William D. Eldred, Beth A. Cimini, Kent T. Keyser, Christianne E. Strang, Virginia E. Wotring
Publikováno v:
The Journal of Comparative Neurology. 507:1952-1963
Although acetylcholine is one of the most widely studied neurotransmitters in the retina, many questions remain about its downstream signaling mechanisms. In this study we initially characterized the cholinergic neurotransmitter system in the salaman
Publikováno v:
The Journal of Comparative Neurology. 505:158-165
Hydrogen sulfide (H2S) is a gaseous neuromodulator that can be synthesized by the transsulfuration enzymes cystathionine -synthase (CBS) and cystathionine -lyase (CGL). In this study we examined H2S as a potential neuromodulator in vertebrate retina.
Autor:
William D. Eldred, Daniel Morton, Frank S. Menniti, A.B. Jakowski, Z. Xie, Wendy O. Adamowicz, Diane Stephenson, Robin J. Kleiman, Christine A. Strick, Robert D. Williams
Publikováno v:
Neuroscience. 139:597-607
PDE10A is a recently identified phosphodiesterase that is highly expressed by the GABAergic medium spiny projection neurons of the mammalian striatum. Inhibition of PDE10A results in striatal activation and behavioral suppression, suggesting that PDE
Autor:
William D. Eldred, Todd A. Blute
Publikováno v:
Vision Research. 45:3469-3486
Nitric oxide (NO) is the most widespread signaling molecule found in the retina in that it can be made by every retinal cell type. NO is able to influence a wide variety of synaptic mechanisms ranging from increasing or decreasing neurotransmitter re