Zobrazeno 1 - 10
of 615
pro vyhledávání: '"William D Leslie"'
Autor:
Bo Zhao, Maria E Suarez-Almazor, Hui Zhao, Noha Abdel-Wahab, Juan Ignacio Ruiz, William D Leslie, Carrie Ye
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Background Immune checkpoint inhibitors (ICIs) can cause severe and sometimes long-standing immune-related adverse events (irAEs). Enhanced immune activation from ICI can theoretically result in osteoclast activation, bone loss and fracture. The obje
Externí odkaz:
https://doaj.org/article/cc378f40442147f6a915ba9498d1f50a
Autor:
Amani F Hamad, Lin Yan, William D Leslie, Suzanne N Morin, Shuman Yang, Randy Walld, Leslie L Roos, Lisa M Lix
Publikováno v:
International Journal of Population Data Science, Vol 5, Iss 5 (2020)
Introduction Major osteoporotic fractures (MOF) are associated with significant morbidity and healthcare system burden. Objectives and Approach We aimed to determine whether sibling fracture history is associated with MOF risk amongst individuals
Externí odkaz:
https://doaj.org/article/b8a4ada82bc14e6ba8c02c6c609b3189
Autor:
Vincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P Kemp, Maria Nethander, Daniel Evans, John A Morris, Douglas P Kiel, Fernando Rivadeneira, Helena Johansson, Nicholas C Harvey, Dan Mellström, Magnus Karlsson, Cyrus Cooper, David M Evans, Robert Clarke, John A Kanis, Eric Orwoll, Eugene V McCloskey, Claes Ohlsson, Joelle Pineau, William D Leslie, Celia M T Greenwood, J Brent Richards
Publikováno v:
PLoS Medicine, Vol 17, Iss 7, p e1003152 (2020)
BackgroundSince screening programs identify only a small proportion of the population as eligible for an intervention, genomic prediction of heritable risk factors could decrease the number needing to be screened by removing individuals at low geneti
Externí odkaz:
https://doaj.org/article/8be8dd60af7343b8a9aa0f6e09d1e428
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189168 (2017)
International Classification of Diseases (ICD) codes have been used to ascertain individuals who are obese. There has been limited research about the predictive value of ICD-coded obesity for major chronic conditions at the population level. We teste
Externí odkaz:
https://doaj.org/article/24099954e5154a5f9cb0e3a7ed5d116f
Autor:
Donald R Duerksen, William D Leslie
Publikováno v:
Canadian Journal of Gastroenterology, Vol 24, Iss 2, Pp 103-107 (2010)
BACKGROUND: Low bone density and osteoporosis have been demonstrated in celiac disease populations in Europe, South America and the United States. Serological testing with tissue transglutaminase (TTG) and immunoglobulin A endomysial (EMA) antibodies
Externí odkaz:
https://doaj.org/article/12a72723451e41d4aa82ec0b9abe32bb
Publikováno v:
Canadian Respiratory Journal, Vol 2, Iss 3, Pp 179-182 (1995)
The perfusion lung scan is a valuable noninvasive tool in the evaluation of patients with pulmonary arterial hypertension of undetermined cause and for the exclusion of occult large-vessel pulmonary thromboembolism. Peripheral patchy defects have bee
Externí odkaz:
https://doaj.org/article/d79b0194b0864724925b6de2433fcbfa
Autor:
Hou-Feng Zheng, Jon H Tobias, Emma Duncan, David M Evans, Joel Eriksson, Lavinia Paternoster, Laura M Yerges-Armstrong, Terho Lehtimäki, Ulrica Bergström, Mika Kähönen, Paul J Leo, Olli Raitakari, Marika Laaksonen, Geoffrey C Nicholson, Jorma Viikari, Martin Ladouceur, Leo-Pekka Lyytikäinen, Carolina Medina-Gomez, Fernando Rivadeneira, Richard L Prince, Harri Sievanen, William D Leslie, Dan Mellström, John A Eisman, Sofia Movérare-Skrtic, David Goltzman, David A Hanley, Graeme Jones, Beate St Pourcain, Yongjun Xiao, Nicholas J Timpson, George Davey Smith, Ian R Reid, Susan M Ring, Philip N Sambrook, Magnus Karlsson, Elaine M Dennison, John P Kemp, Patrick Danoy, Adrian Sayers, Scott G Wilson, Maria Nethander, Eugene McCloskey, Liesbeth Vandenput, Richard Eastell, Jeff Liu, Tim Spector, Braxton D Mitchell, Elizabeth A Streeten, Robert Brommage, Ulrika Pettersson-Kymmer, Matthew A Brown, Claes Ohlsson, J Brent Richards, Mattias Lorentzon
Publikováno v:
PLoS Genetics, Vol 8, Iss 7, p e1002745 (2012)
We aimed to identify genetic variants associated with cortical bone thickness (CBT) and bone mineral density (BMD) by performing two separate genome-wide association study (GWAS) meta-analyses for CBT in 3 cohorts comprising 5,878 European subjects a
Externí odkaz:
https://doaj.org/article/7b3188ad8d0c47259dc91c1ace3fc2aa
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14045 (2010)
Development of novel methodologies to efficiently create large genetic epidemiology cohorts is needed. Here we describe a rapid, precise and cost-efficient method for collection of DNA from cases previously experiencing an osteoporotic fracture by id
Externí odkaz:
https://doaj.org/article/247469c3080b41e7bbc1cd2c70d365f2
Publikováno v:
Osteoporosis International. 34:1085-1091
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cae7f6edcd6eddea42016f7062b5351
https://doi.org/10.1007/s00198-023-06722-w
https://doi.org/10.1007/s00198-023-06722-w
Publikováno v:
Osteoporosis International. 34:735-740
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968bef998ea5c51c95b6276a1fffdd4e
https://doi.org/10.1007/s00198-023-06690-1
https://doi.org/10.1007/s00198-023-06690-1