Zobrazeno 1 - 10
of 27
pro vyhledávání: '"William D Holmes"'
Autor:
Sonal A. Parikh, BS, Syril Keena T. Que, MD, William D. Holmes, MD, Katalin Ferenczi, MD, Jane M. Grant-Kels, MD, Marti Jill Rothe, MD
Publikováno v:
International Journal of Women's Dermatology, Vol 1, Iss 3, Pp 131-135 (2015)
Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomi
Externí odkaz:
https://doaj.org/article/1eccc8a2a01f42afa0c8c1f9b2cd7df3
Autor:
Bo Qi, Stanley Ng, Richard Chen, Martha L Healy-Fried, Josaih C Adaelu, Rajesh Ambat, Paul Balderes, Julia Lee, Troii Hall, Yun (Kenneth) Kang, Behnam Shanehsaz, William D Holmes, Dale L. Ludwig, Michael Barry, Matthew D Sauffer, Warren R. Emery, Amy Huebner
Publikováno v:
Pharmaceutical Bioprocessing. 3:477-487
6-Chloro- and 6-bromopurines can cross the blood-brain barrier and in situ give rise to substrates of multidrug resistance-associated proteins (MRPs). The electrophilic purines form glutathione conjugates in reactions catalyzed by intracellular gluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf6e25f7cec067196cbc97bda8b19af
https://doi.org/10.4155/pbp.15.28
https://doi.org/10.4155/pbp.15.28
Autor:
William D. Holmes, Sonal A. Parikh, Katalin Ferenczi, Jane M. Grant-Kels, Marti J. Rothe, Syril Keena T. Que
Publikováno v:
International Journal of Women's Dermatology
International Journal of Women's Dermatology, Vol 1, Iss 3, Pp 131-135 (2015)
International Journal of Women's Dermatology, Vol 1, Iss 3, Pp 131-135 (2015)
Actinic granuloma is a rare granulomatous reaction that is more commonly seen in females and thought to occur as an autoimmune response to actinic damage of elastic tissue. We discuss a case of a patient with actinic granuloma presenting with concomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19742f0bd1b76d358edd921345303fac
Autor:
William D. Holmes
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 57:S86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422047f5a060213426ceff859ea0cca3
https://doi.org/10.1016/j.jaac.2018.07.362
https://doi.org/10.1016/j.jaac.2018.07.362
Publikováno v:
Protein Expression and Purification. 21:367-377
Stromal-cell-derived factor-1 (SDF-1alpha) is an 8-kDa chemokine that is constitutively expressed in bone-marrow-derived stromal cells and has been identified as a ligand for the CXCR4 receptor. We produced the chemokine recombinantly as methionine-S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a881498680eb62d32ea36de3bb9fdc
https://doi.org/10.1006/prep.2001.1402
https://doi.org/10.1006/prep.2001.1402
Autor:
David D. McKee, Roderick G. Davis, John T. Moore, Byron Ellis, Lisa M. Shewchuk, William D. Holmes, Anne M. Hassell, Earnest Horne, Sue H. Kadwell
Publikováno v:
Structure. 8:1105-1113
Background: Angiogenesis, the formation of new vessels from the existing vasculature, is a critical process during early development as well as in a number of disease processes. Tie2 (also known as Tek) is an endothelium-specific receptor tyrosine ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff6d448312d095521df95e452e5b2c4
https://doi.org/10.1016/s0969-2126(00)00516-5
https://doi.org/10.1016/s0969-2126(00)00516-5
Autor:
William D. Holmes, Michael A. Luther, Susan Armour, Channa K Jayawickreme, Grace Chen, Larry Boone, Wen Ji Chen, Walter S. Dallas, Robert G. Ferris, Chris Watson, Larry Wolfe, Terry P. Kenakin
Publikováno v:
Molecular Pharmacology. 53:177-181
This article describes the transient expression of the CXC chemokine receptor-4 in Xenopus laevis melanophores and the resulting functional assay for the endogenous ligand for this receptor stromal cell-derived factor (SDF)-1alpha. Specifically, it w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f4db6101ebd80fbe21783b28bd8aed
https://doi.org/10.1124/mol.53.2.177
https://doi.org/10.1124/mol.53.2.177
Autor:
William D. Holmes, Timothy N. C. Wells, Michael A. Luther, Mette M. Rosenkilde, Lawrence F. Brass, Annegret Pelchen-Matthews, James A. Hoxie, Mark Marsh, Joanne Oldridge, Walt Dallas, Per Johan Klasse, Thanh Tran, Natalie Signoret, Thue W. Schwartz
Publikováno v:
The Journal of Cell Biology
The chemokine receptor CXCR4 is required, together with CD4, for entry by some isolates of HIV-1, particularly those that emerge late in infection. The use of CXCR4 by these viruses likely has profound effects on viral host range and correlates with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec19d8ce5955df20bac30777d4d4f782
https://doi.org/10.1083/jcb.139.3.651
https://doi.org/10.1083/jcb.139.3.651
Autor:
Sue H. Kadwell, G B Wisely, Derril H. Willard, Zajac-Thompson I, Christine R. Hoffman, Michael A. Luther, G. Tian, I R Patel, William C. Clay, William D. Holmes, Jeffrey S. Wiseman, Warren J. Rocque
Publikováno v:
Biochemistry. 36:14250-14261
The interactions between (R)-rolipram and purified human recombinant low-Km, cAMP-specific phosphodiesterase (HSPDE4B2B) constructs were investigated using biochemical, kinetic, and biophysical approaches. The full-length protein (amino acids 1-564)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64705e7668ed56456b68255c06627014
https://doi.org/10.1021/bi971112e
https://doi.org/10.1021/bi971112e
Autor:
Michael A. Luther, Laurie K. Overton, Christine R. Hoffman, Ittoop O, Warren J. Rocque, I R Patel, Derril H. Willard, G B Wisely, Dougherty Rw, William D. Holmes
Publikováno v:
Protein Expression and Purification. 9:191-202
We have overexpressed in a baculovirus expression system, and purified to > 95% homogeneity, milligram quantities of a human recombinant rolipram-sensitive cAMP phosphodiesterase, HSPDE4B2B (amino acid residues 81-564). The protein expression levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cbe1b49484c5d683c3f20c48f3451b
https://doi.org/10.1006/prep.1996.0683
https://doi.org/10.1006/prep.1996.0683