Zobrazeno 1 - 10
of 515
pro vyhledávání: '"William D, Rawlinson"'
Autor:
Anouschka Akerman, Christina Fichter, Vanessa Milogiannakis, Camille Esneau, Mariana Ruiz Silva, Tim Ison, Joseph A. Lopez, Zin Naing, Joanna Caguicla, Supavadee Amatayakul-Chantler, Nathan Roth, Sandro Manni, Thomas Hauser, Thomas Barnes, Tino Boss, Anna Condylios, Malinna Yeang, Kenta Sato, Nathan N. Bartlett, David Darley, Gail Matthews, Damien J. Stark, Susan Promsri, William D. Rawlinson, Benjamin Murrell, Anthony D. Kelleher, Dominic Dwyer, Vitali Sintchenko, Jen Kok, Sally Ellis, Kelsi Marris, Elizabeth Knight, Veronic C. Hoad, David O. Irving, Iain Gosbell, Fabienne Brilot, James Wood, Anupriya Aggarwal, Stuart G. Turville
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105415- (2024)
Summary: Background: Continued phenotyping and ongoing molecular epidemiology are important in current and future monitoring of emerging SARS-CoV-2 lineages. Herein we developed pragmatic strategies to track the emergence, spread and phenotype of SAR
Externí odkaz:
https://doaj.org/article/1b1cbecf52be4522ab1f6d136998b43a
Autor:
Ece Egilmezer, Stuart T. Hamilton, Charles S. P. Foster, Manfred Marschall, William D. Rawlinson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Human cytomegalovirus (CMV) infection is the leading non-genetic aetiology of congenital malformation in developed countries, causing significant fetal neurological injury. This study investigated potential CMV pathogenetic mechanisms of fet
Externí odkaz:
https://doaj.org/article/d6dea77e2f39409cb1b7a2d949208ac3
Autor:
Manfred Marschall, Martin Schütz, Markus Wild, Eileen Socher, Christina Wangen, Kishore Dhotre, William D. Rawlinson, Heinrich Sticht
Publikováno v:
Cells, Vol 13, Iss 16, p 1338 (2024)
Herpesviral protein kinases, such as the therapy-relevant pUL97 of human cytomegalovirus (HCMV), are important for viral replication efficiency as well as pathogenesis, and represent key antiviral drug targets. HCMV pUL97 is a viral cyclin-dependent
Externí odkaz:
https://doaj.org/article/701343dc21c342d0b556c8f8649ac032
Autor:
Leonard C Harrison, Esther Bandala‐Sanchez, Helena Oakey, Peter G Colman, Kelly Watson, Ki Wook Kim, Roy Wu, Emma E Hamilton‐Williams, Natalie L Stone, Aveni Haynes, Rebecca L Thomson, Peter J Vuillermin, Georgia Soldatos, William D Rawlinson, Kelly J McGorm, Grant Morahan, Simon C Barry, Richard O Sinnott, John M Wentworth, Jennifer J Couper, Megan AS Penno, the ENDIA Study Group
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 9, Pp 1092-1100 (2023)
ABSTRACT Aims/Introduction Autoantibodies to pancreatic islet antigens identify young children at high risk of type 1 diabetes. On a background of genetic susceptibility, islet autoimmunity is thought to be driven by environmental factors, of which e
Externí odkaz:
https://doaj.org/article/993f04912a044005ba462f8d64f9e9e5
Autor:
Ece Egilmezer, Stuart T. Hamilton, Glen Lauw, Jasmine Follett, Eric Sonntag, Martin Schütz, Manfred Marschall, William D. Rawlinson
Publikováno v:
Viruses, Vol 16, Iss 6, p 918 (2024)
Human cytomegalovirus (CMV) infection is the leading non-genetic cause of congenital malformation in developed countries, causing significant fetal injury, and in some cases fetal death. The pathogenetic mechanisms through which this host-specific vi
Externí odkaz:
https://doaj.org/article/af26405dbaf94078be2097abd1e33dd0
Autor:
Susan J. Matthews, Kelcie Miller, Kelly Andrewartha, Melisa Milic, Deane Byers, Peter Santosa, Alexa Kaufer, Kirsty Smith, Louise M. Causer, Belinda Hengel, Ineka Gow, Tanya Applegate, William D. Rawlinson, Rebecca Guy, Mark Shephard
Publikováno v:
Diagnostics, Vol 14, Iss 11, p 1106 (2024)
In April 2020, the Aboriginal and Torres Strait Islander COVID-19 Point-of-Care (POC) Testing Program was initiated to improve access to rapid molecular-based SARS-CoV-2 detection in First Nations communities. At capacity, the program reached 105 hea
Externí odkaz:
https://doaj.org/article/948f7257b68844dbb06e34ff2cb7afb4
Autor:
Helena Oakey, Lynne C. Giles, Rebecca L. Thomson, Kim-Anh Lê Cao, Pat Ashwood, James D. Brown, Emma J. Knight, Simon C. Barry, Maria E. Craig, Peter G. Colman, Elizabeth A. Davis, Emma E. Hamilton-Williams, Leonard C. Harrison, Aveni Haynes, Ki Wook Kim, Kylie-Ann Mallitt, Kelly McGorm, Grant Morahan, William D. Rawlinson, Richard O. Sinnott, Georgia Soldatos, John M. Wentworth, Jennifer J. Couper, Megan A. S. Penno
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground: The Environmental Determinants of Islet Autoimmunity (ENDIA) pregnancy-birth cohort investigates the developmental origins of type 1 diabetes (T1D), with recruitment between 2013 and 2019. ENDIA is the first study in the world wit
Externí odkaz:
https://doaj.org/article/4020f54528be4126a735e523a39a8616
Autor:
Romain Rouet, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L. Burnett, Simon H. J. Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J. Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C. Goodnow, Stuart G. Turville, William D. Rawlinson, Rowena A. Bull, Alastair G. Stewart, Philip M. Hansbro, Daniel Christ
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here, Rouet et al. present a strategy for the identification of broadly neutralising antibodies against SARS-CoV-2 receptor binding domain from peripheral blood mononuclear cells of convalescent patients, which enabled the identification of a new cla
Externí odkaz:
https://doaj.org/article/d7c35bcc59bc4a9fb845343c96f9aa30
Autor:
Martin Schütz, Christina Wangen, Mona Sommerer, Melanie Kögler, Jan Eickhoff, Carsten Degenhart, Bert Klebl, Zin Naing, Ece Egilmezer, Stuart T. Hamilton, William D. Rawlinson, Heinrich Sticht, Manfred Marschall
Publikováno v:
Virus Research, Vol 335, Iss , Pp 199200- (2023)
Human cytomegalovirus (HCMV) infection is shaped by a tightly regulated interplay between viral and cellular proteins. Distinct kinase activities, such as the viral cyclin-dependent kinase ortholog (vCDK) pUL97 and cellular CDK7 are both crucial for
Externí odkaz:
https://doaj.org/article/ac8f839330fc4cb29be6a6ece1547fd9
Autor:
Christopher Hodgkins, Laura K. Buckton, Gregory J. Walker, Ben Crossett, Stuart J. Cordwell, Andrea R. Horvath, William D. Rawlinson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has primarily been achieved using reverse transcriptase polymerase chain reaction (RT-PCR) for acute infection, and serology for prior infection. Assay with
Externí odkaz:
https://doaj.org/article/4369c81ba32a40c79646a52b480ddba0