Zobrazeno 1 - 10
of 29
pro vyhledávání: '"William D, Andrews"'
Autor:
Chih-Yao Chung, Kritarth Singh, Vassilios N. Kotiadis, Gabriel E. Valdebenito, Jee Hwan Ahn, Emilie Topley, Joycelyn Tan, William D. Andrews, Benoit Bilanges, Robert D. S. Pitceathly, Gyorgy Szabadkai, Mariia Yuneva, Michael R. Duchen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Heteroplasmic mtDNA mutations cause disease in humans. Here, Chung et al find the PI3K-Akt-mTORC1 pathway constitutively activated in cells with the heteroplasmic m.3243 A > G mutation, and inhibition of the pathway cell autonomously reduces mutant m
Externí odkaz:
https://doaj.org/article/b9f6630675044451be3ddb118624adeb
Autor:
William D. Andrews, Arianna Zito, Fani Memi, Gareth Jones, Nobuaki Tamamaki, John G. Parnavelas
Publikováno v:
Biology Open, Vol 2, Iss 3, Pp 277-282 (2013)
Summary En route to the neocortex, interneurons migrate around and avoid the developing striatum. This is due to the chemorepulsive cues of class 3 semaphorins (Sema3A and Sema3F) acting through neuropilin and plexin co-receptors expressed in interne
Externí odkaz:
https://doaj.org/article/c3acda57bc9e48eeb94fef4b0fa83ece
Autor:
Thomas M. Piers, Jennifer M. Pocock, Dervis A. Salih, Anna Mallach, William D Andrews, Andrew C Graham, Wenfei Liu, John Hardy, Sevinc Bayram, Rui Wang, Orjona Taso, Pablo Garcia-Reitboeck, Damian M. Cummings, Frances A. Edwards, Juan A. Botía
Publikováno v:
Human Molecular Genetics
Genome-wide association studies have reported that, amongst other microglial genes, variants in TREM2 can profoundly increase the incidence of developing Alzheimer’s disease (AD). We have investigated the role of TREM2 in primary microglial culture
Autor:
Wenfei Liu, Orjona Taso, Rui Wang, Sevinc Bayram, Pablo Garcia-Reitboeck, Anna Mallach, William D. Andrews, Thomas M. Piers, Andrew C. Graham, Juan A. Botia, Jennifer M. Pocock, Damian M. Cummings, John Hardy, Frances A. Edwards, Dervis A. Salih
Genome-wide association studies have reported that, amongst other microglial genes, variants inTREM2can profoundly increase the incidence of developing Alzheimer’s disease (AD). We have investigated the role of TREM2 in primary microglial cultures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b552292ab6b0c3a3ab36afe72cd523
Autor:
Melissa, Barber, William D, Andrews, Fani, Memi, Phillip, Gardener, Daniel, Ciantar, Mathew, Tata, Christiana, Ruhrberg, John G, Parnavelas
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 28(7)
Vascular endothelial growth factor (Vegfa) is essential for promoting the vascularization of the embryonic murine forebrain. In addition, it directly influences neural development, although its role in the forming forebrain is less well elucidated. I
Autor:
William D. Andrews
Danger has found museum director Julie Williamson once again when an annual convention of historical society directors puts her in the path of a troubled colleague. Precious artifacts are missing and landing in the hands of unscrupulous dealers to th
Autor:
Pei-Ju Sung, Michael J. Tilby, Robert F. Newbold, William D. Andrews, Deborah A. Tweddle, Nidal Boulos, John Lunec
Publikováno v:
Cancer Letters. 328:168-175
To better understand neuroblastoma differentiation, we used microarray analysis to identify common gene expression changes from three differentiation models. This revealed STMN4 and ROBO2 to be consistently up-regulated in differentiated neuroblastom
A perennially popular book with highly regarded authorship.Features:Addition of a new co-author, Peter J. Wiedenbeck of Washington University in St. Louis.Thorough updating throughout.Shortened to accommodate today s typical 3-credit, 13-week course.
Autor:
David Wellsted, Shelley Brown, Francis G Gabriel, Stephen A. Bustin, Neerja Agrawal, Jade B Collard, Anthony Aylwin, Mo Keshtgar, Evdokia Arkoumani, S. Holt, Priya Sai-Giridhar, Preethi Gopinath, Ian A. Cree, Salma Al-Ramadhani, Margaret J. Jeffrey, Salam Al-Sam, Samar Jader, Hema Chaplin, Soha El Sheikh, Dilushana George, Yousef Sharaiha, Stephanie Jenkins, Alison Findlay, Robert E. Mansel, Howard Bradpiece, J. McKenzie, William D. Andrews, A. McDowell, Avi Agrawal, Vasi Sundaresan, Maryse Sundaresan, Olfert Landt, Constantinos Yiangou, Nuala McDermott
Aims:\ud \ud Treatment strategies for breast cancer continue to evolve. No uniformity exists in the UK for the management of node‐positive breast cancer patients. Most centres continue to use conventional histopathology of sampled sentinel lymph no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb874e7ba14470fdf45a2f57930a1e0
https://arro.anglia.ac.uk/id/eprint/705214/1/Sai-Giridhar_et_al_2016.pdf
https://arro.anglia.ac.uk/id/eprint/705214/1/Sai-Giridhar_et_al_2016.pdf
Autor:
Shinichi Kohsaka, Shigeo Uchino, John G. Parnavelas, Carina Hanashima, Yuko Gonda, William D. Andrews, Hidenori Tabata, Takashi Namba, Kazunori Nakajima
Publikováno v:
Cerebral Cortex. 23:1495-1508
Laminar organization is a key feature of the mammalian cerebral cortex, but the mechanisms by which final positioning and “inside-out” distribution of neurons are determined remain largely unknown. Here, we demonstrate that Robo1, a member of the