Zobrazeno 1 - 10 of 33 pro vyhledávání: '"William Cushley"'
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Analysis of the CD23-αv integrin interaction: A study with model peptides
Autor: William Cushley, Adrienne L. Edkins, Richard J. Cogdell, Bradford W. Ozanne, Gillian Borland, Sharon M. Kelly
Publikováno v: Biochemical and Biophysical Research Communications. 422:207-212
The human CD23 protein binds to αvβ3 and αvβ5 integrins. The integrins recognize a short tripeptide motif of arg-lys-cys (RKC) in CD23, and peptides containing this motif inhibit the binding of CD23 to B cells and monocytes; neither fibronectin,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dd7c84656d171fadcbebb0f20c2fe5
https://doi.org/10.1016/j.bbrc.2012.04.076
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3
Differential regulation of monocyte cytokine release by αV and β2 integrins that bind CD23
Autor: Bradford W. Ozanne, William Cushley, Richard J. Cogdell, Gillian Borland, Adrienne L. Edkins, Mridu Acharya
Publikováno v: Immunology. 136:241-251
The human soluble CD23 (sCD23) protein displays highly pleiotropic cytokine-like activity. Monocytic cells express the sCD23-binding integrins αVβ(3), αVβ(5), αMβ(2) and αXβ(2), but it is unclear which of these four integrins most acutely reg
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f091ec6941e19464a0f4c690061396fe
https://doi.org/10.1111/j.1365-2567.2012.03576.x
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4
Epstein–Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival
Autor: William Cushley, Yazeed A. Al-Sheikh, Mark E. Drotar, Joanna B. Wilson, Penelope M. Tsimbouri
Publikováno v: Journal of General Virology. 89:2821-2832
Epstein–Barr virus nuclear antigen-1 (EBNA-1) is the only latent protein expressed in all virus-associated tumours. It plays a critical role in viral propagation and in the replication, episomal maintenance and partitioning of the viral genome. How
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca92565505ce8c5a2ddfbedf625f624
https://doi.org/10.1099/vir.0.83296-0
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5
The antimitotic effect of the neem terpenoid azadirachtin on cultured insect cells
Autor: Roger L. P. Adams, R.H.C. Strang, William Cushley, John R. Kusel, A. Akhkha, A. Salehzadeh
Publikováno v: Insect Biochemistry and Molecular Biology. 33:681-689
When cultured insect cells (Sf9) were grown in the presence of 5 x 10(-6) M azadirachtin, there was a rapid increase in the mitotic index, with the appearance of many aberrant mitotic figures. Flow cytometry established that cells accumulated in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fdf71a06bea158c163ae5353a07f431
https://doi.org/10.1016/s0965-1748(03)00057-2
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6
Inhibition of Apoptosis in a Human Pre-B–Cell Line by CD23 Is Mediated Via a Novel Receptor
Autor: Lindsey J. White, William Cushley, Bradford W. Ozanne, Jean-Pierre Aubry, Jean-Yves Bonnefoy, Pierre Graber
Publikováno v: Blood. 90:234-243
Human CD23 is a 45-kD type II membrane glycoprotein, which functions as a low-affinity receptor for IgE and as a ligand for the CD21 and CD11b/CD11c differentiation antigens. CD23 is released from the surface of cells as soluble fragments, and a 25-k
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a27516c789bafc62fa931ebaf78142
https://doi.org/10.1182/blood.v90.1.234
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8
Soluble CD40 ligand induces expression of CD25 and CD23 in resting human tonsillar B lymphocytes
Autor: Pierre Graber, Jean-Yves Bonnefoy, Bradford W. Ozanne, William Cushley, Ellen L. Burlinson
Publikováno v: European Journal of Immunology. 26:1069-1073
In this report, we describe the dose-dependent increase in both CD25 and CD23 levels on resting human B cells in response to CD40 ligation, as mediated by soluble CD40 ligand (sCD40L) or anti-CD40 antibody. In combination with interleukin (IL)-4, sCD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055def9f354aa95b1656b1dc2dd4653b
https://doi.org/10.1002/eji.1830260517
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9
Positioning the immune system: unexpected roles for alpha6-integrins
Autor: William Cushley, Gillian Borland
Publikováno v: Immunology. 111:381-383
Accurate initiation and regulation of immune responses requires the dynamic recruitment and retention of lymphocytes in lymphoid tissue. It is now well accepted that the cells of the innate and adaptive immune systems reposition themselves in respons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88794148b23e50b47cc88287f21f583
https://doi.org/10.1111/j.0019-2805.2004.01838.x
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10
Anti-immunoglobulin and anti-CD40 stimulation induces CD25 expression by resting human tonsillar B lymphocytes
Autor: William Cushley, Ellen L. Burlinson, Bradford W. Ozanne, Heather M. Pringle
Publikováno v: Immunology Letters. 45:93-98
In this report, the effect of ligation of a number of B-cell surface molecules upon expression of CD25, the 55-kDa inducible component of the IL-2 receptor complex found on T and B lymphocytes, is reported. IL-4 is the only cytokine apparently capabl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::066d746a24ecde1f44eab772692fb41c
https://doi.org/10.1016/0165-2478(94)00232-g
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