Zobrazeno 1 - 10
of 36
pro vyhledávání: '"William Cruz-Munoz"'
Autor:
Harriet M. Kluger, Yuval Kluger, Ruth Halaban, Marcus W. Bosenberg, David L. Rimm, Robert S. Kerbel, William Cruz-Munoz, Christopher R. Zito, Meaghan L. Barr, Fabio Parisi, Lucia B. Jilaveanu
Kaplan-Meier curves for PLEKHA5 expression and development of other distant metastases. There was no correlation between expression and time to development of lung, liver or bone metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1322a8ed6dd8f2cb41e117126e530f75
https://doi.org/10.1158/1078-0432.22459497
https://doi.org/10.1158/1078-0432.22459497
Autor:
Harriet M. Kluger, Yuval Kluger, Ruth Halaban, Marcus W. Bosenberg, David L. Rimm, Robert S. Kerbel, William Cruz-Munoz, Christopher R. Zito, Meaghan L. Barr, Fabio Parisi, Lucia B. Jilaveanu
Purpose: Approximately 40% of patients with metastatic melanoma develop brain metastases. Our purpose was to identify genes aberrantly expressed in melanoma that might be associated with propensity for brain homing.Experimental Design: We studied gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ce4ef18b0624d99674c772fed3b428
https://doi.org/10.1158/1078-0432.c.6524232
https://doi.org/10.1158/1078-0432.c.6524232
Autor:
Harriet M. Kluger, Yuval Kluger, Ruth Halaban, Marcus W. Bosenberg, David L. Rimm, Robert S. Kerbel, William Cruz-Munoz, Christopher R. Zito, Meaghan L. Barr, Fabio Parisi, Lucia B. Jilaveanu
This file provides legends for Supplementary Figures S1, S2, S3 and S4. Figure S1 contains Kaplan Meier survival curves for PLEKHA5 expression and metastases to various sites, Figures S2 and S3 show Western blots demonstrating PLEKHA5 expression in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470cb38e015836fb5ab6f36eceae26f6
https://doi.org/10.1158/1078-0432.22459500.v1
https://doi.org/10.1158/1078-0432.22459500.v1
Autor:
Harriet M. Kluger, Yuval Kluger, Ruth Halaban, Marcus W. Bosenberg, David L. Rimm, Robert S. Kerbel, William Cruz-Munoz, Christopher R. Zito, Meaghan L. Barr, Fabio Parisi, Lucia B. Jilaveanu
Supplementary Table S3: This table provides the results of a multivariable Cox proportional hazards analysis of PLEKHA5 and other clinical variables. PLEKHA5 was independently associated with development of early brain metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bf09377875585497bd101ec7aeb932
https://doi.org/10.1158/1078-0432.22459476
https://doi.org/10.1158/1078-0432.22459476
Autor:
Harriet M. Kluger, Yuval Kluger, Ruth Halaban, Marcus W. Bosenberg, David L. Rimm, Robert S. Kerbel, William Cruz-Munoz, Christopher R. Zito, Meaghan L. Barr, Fabio Parisi, Lucia B. Jilaveanu
This file provides additional details regarding methods for RNA extraction and quality control, gene expression profiling and analysis, immunofluorescence staining and cell lines used. It also contains information on the siRNA knock-down studies, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b2a2961d83ac73eaa023e6251392bd
https://doi.org/10.1158/1078-0432.22459485.v1
https://doi.org/10.1158/1078-0432.22459485.v1
Publikováno v:
EMBO Molecular Medicine
Anti‐angiogenic drugs targeting the VEGF pathway are most effective in advanced metastatic disease settings of certain types of cancers, whereas they have been unsuccessful as adjuvant therapies of micrometastatic disease in numerous phase III tria
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
Conventional maximum‐tolerated dose (MTD) chemotherapy relies on periodic, massive cancer cell ablation events followed by treatment‐free intermissions, stereotypically resulting in resistance, relapse, and mortality. Furthermore, MTD chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fa1fd9b9770ceb356bbbb0e25bc367
Autor:
Annabelle Chow, Ping Xu, Shan Man, Robert S. Kerbel, José L. Ponce de Léon, Yuval Shaked, Kabir A. Khan, William Cruz-Munoz, Madeleine Benguigui
Publikováno v:
npj Breast Cancer
npj Breast Cancer, Vol 6, Iss 1, Pp 1-13 (2020)
NPJ Breast Cancer
npj Breast Cancer, Vol 6, Iss 1, Pp 1-13 (2020)
NPJ Breast Cancer
The impressive successes of immune checkpoint blockade antibodies to treat various types of cancer are limited to minor subsets of patients. Combination therapy strategies, including with chemotherapy, are being explored to possibly improve the effic
Autor:
Ping Xu, Alicia Viloria-Petit, William Cruz-Munoz, Robert S. Kerbel, Geoffrey A. Wood, Denise Hileeto, Raquel Muñoz, Shan Man
Publikováno v:
UVaDOC: Repositorio Documental de la Universidad de Valladolid
Universidad de Valladolid
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0222580 (2019)
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
Universidad de Valladolid
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0222580 (2019)
UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname
Producción Científica
Metronomic chemotherapy using the 5-FU prodrug uracil-tegafur (UFT) and cyclophosphamide (CTX) was previously shown to only modestly delay primary tumor growth, but nevertheless markedly suppressed the development of micr
Metronomic chemotherapy using the 5-FU prodrug uracil-tegafur (UFT) and cyclophosphamide (CTX) was previously shown to only modestly delay primary tumor growth, but nevertheless markedly suppressed the development of micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b14acdee354daf738a3bb4b99b348a8
https://doi.org/10.1371/journal.pone.0222580
https://doi.org/10.1371/journal.pone.0222580
Autor:
David L. Rimm, Ruth Halaban, Meaghan L. Barr, Yuval Kluger, Harriet M. Kluger, Fabio Parisi, William Cruz-Munoz, Robert S. Kerbel, Lucia B. Jilaveanu, Marcus Bosenberg, Christopher R. Zito
Publikováno v:
Clinical Cancer Research. 21:2138-2147
Purpose: Approximately 40% of patients with metastatic melanoma develop brain metastases. Our purpose was to identify genes aberrantly expressed in melanoma that might be associated with propensity for brain homing. Experimental Design: We studied ge