Zobrazeno 1 - 8
of 8
pro vyhledávání: '"William Comb"'
Autor:
Tanya M. Holloway, Chris McGlory, Sean McKellar, Adrienne Morgan, Mike Hamill, Raffi Afeyan, William Comb, Scharmen Confer, Peng Zhao, Mark Hinton, Olga Kubassova, Manu V. Chakravarthy, Stuart M. Phillips
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Skeletal muscle disuse leads to atrophy, declines in muscle function, and metabolic dysfunction that are often slow to recover. Strategies to mitigate these effects would be clinically relevant. In a double-blind randomized-controlled pilot trial, we
Externí odkaz:
https://doaj.org/article/16c8bddee18c48e1b90b161d17df06ba
Autor:
Nimish Gera, Kyle Fitzgerald, Vijay Ramesh, Purvi Patel, Lena Kien, Deepak Kanojia, Simon Aoyama, Federico Colombo, Amit Deshpande, William Comb, Thomas Chittenden, Brian Fiske
Publikováno v:
Cancer Research. 83:5000-5000
MET alterations can act as an oncogenic driver in non-small cell lung cancer (NSCLC) and elevated cMET expression occurs in many cancers. Antibody drug conjugates targeting cMET (cMET-ADCs) have been developed as a strategy to treat cMET+ tumors irre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::751199aaeebee84e2b209d0539aa6715
https://doi.org/10.1158/1538-7445.am2023-5000
https://doi.org/10.1158/1538-7445.am2023-5000
Autor:
Sean M. Carroll, Tony Tramontin, Michael Hamill, Manu V. Chakravarthy, Peng Zhao, Sam Rebello, Noriaki Tatsuta, Scharmen Confer, Joel Neutel, Arun J. Sanyal, William Comb, Raffi Afeyan
Publikováno v:
Clinical and Translational Gastroenterology
INTRODUCTION: AXA1665 is a novel investigational amino acid (AA) composition specifically designed to impact AA imbalance, ammoniagenesis, and dysregulated anabolic activity associated with cirrhosis. METHODS: This 2-part study examined AXA1665 effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65ba87cdfa4c01da49ea516ddee674f
https://pubmed.ncbi.nlm.nih.gov/32955200
https://pubmed.ncbi.nlm.nih.gov/32955200
Autor:
Manu V. Chakravarthy, M. Hinton, Mike Hamill, Peng Zhao, Tanya M. Holloway, Sean R McKellar, Adrienne K Morgan, William Comb, Raffi Afeyan, Scharmen Confer, Stuart M. Phillips, Olga Kubassova, Chris McGlory
Publikováno v:
Frontiers in Nutrition, Vol 6 (2019)
Frontiers in Nutrition
Frontiers in Nutrition
Skeletal muscle disuse leads to atrophy, declines in muscle function, and metabolic dysfunction that are often slow to recover. Strategies to mitigate these effects would be clinically relevant. In a double-blind randomized-controlled pilot trial, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ea72e1846059835ce53c7fc4847762
Autor:
Eric Lawitz, Scharmen Confer, Joel Neutel, William Comb, Jeff Zhao, Andres Duarte-Rojo, Arun J. Sanyal, Jasmohan S. Bajaj, Robert G. Perry, Manu V. Chakravarthy
Publikováno v:
Gastroenterology. 160:S-796
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2768528c519e387f7739949c1e7145da
https://doi.org/10.1016/s0016-5085(21)02620-2
https://doi.org/10.1016/s0016-5085(21)02620-2
Autor:
Shuyu, Wang, Zhi-Yang, Tsun, Rachel L, Wolfson, Kuang, Shen, Gregory A, Wyant, Molly E, Plovanich, Elizabeth D, Yuan, Tony D, Jones, Lynne, Chantranupong, William, Comb, Tim, Wang, Liron, Bar-Peled, Roberto, Zoncu, Christoph, Straub, Choah, Kim, Jiwon, Park, Bernardo L, Sabatini, David M, Sabatini
The mechanistic target of rapamycin complex 1 (mTORC1) protein kinase is a master growth regulator that responds to multiple environmental cues. Amino acids stimulate, in a Rag-, Ragulator-, and vacuolar adenosine triphosphatase-dependent fashion, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::25785da592e12cd032c741839e18239e
https://europepmc.org/articles/PMC4295826/
https://europepmc.org/articles/PMC4295826/
Autor:
Hans Gregersen, Yanmin Wang, Fred Field, Mengjun Wang, Kar Man Lo, Xiaomei Guo, William Combs, Ghassan S. Kassab
Publikováno v:
Physiological Reports, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Several technologies have been developed for assessing anorectal function including the act of defecation. We used a new prototype of the Fecobionics technology, a multi‐sensor simulated feces, to visualize defecatory patterns and introduc
Externí odkaz:
https://doaj.org/article/938712264ad240b5b77804767900e31f
Autor:
Kate E. Coleman, Sheila T. Yong, Thomas Ennis, Melanie Herscovitch, Sushil Chandani, Thomas D. Gilmore, William Comb, Brinda Armstead, Demetrios Kalaitzidis
Publikováno v:
Biochemical and biophysical research communications. 367(1)
NEMO is an essential regulatory component of the IkappaB kinase (IKK) complex, which controls activation of the NF-kappaB signaling pathway. Herein, we show that NEMO exists as a disulfide-bonded dimer when isolated from several cell types and analyz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e417d14fb2cc081a4dc3bee4e823d5ec
https://pubmed.ncbi.nlm.nih.gov/18164680
https://pubmed.ncbi.nlm.nih.gov/18164680