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Computational validation of clonal and subclonal copy number alterations from bulk tumour sequencing
Autor:
Alice Antonello, Riccardo Bergamin, Nicola Calonaci, Jacob Househam, Salvatore Milite, Marc J Williams, Fabio Anselmi, Alberto d’Onofrio, Vasavi Sundaram, Alona Sosinsky, William CH Cross, Giulio Caravagna
Cancer is a global health issue that places enormous demands on healthcare systems. Basic research, the development of targeted treatments, and the utility of DNA sequencing in clinical settings, have been significantly improved with the introduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bf93d9fcbccdf1f2ea0af71003300a
https://doi.org/10.1101/2021.02.13.429885
https://doi.org/10.1101/2021.02.13.429885
Publikováno v:
The Journal of pathology. 240(2)
Evolutionary theories are themselves subject to evolution. Clonal evolution - the model that describes the initiation and progression of cancer - is entering a period of profound change, brought about largely by technological developments in genome a