Zobrazeno 1 - 10
of 15
pro vyhledávání: '"William C.K. Pomerantz"'
Autor:
Fuhar Dixit, Edmund H. Antell, Katharine A. Faber, Chuhui Zhang, Manmeet W. Pannu, Megan H. Plumlee, Jean Van Buren, Abraham Doroshow, William C.K. Pomerantz, William A. Arnold, Christopher P. Higgins, Graham F. Peaslee, Lisa Alvarez-Cohen, David L. Sedlak, Mohamed Ateia
Publikováno v:
Journal of Hazardous Materials Letters, Vol 5, Iss , Pp 100122- (2024)
Multiple poly- and perfluoroalkyl substances (PFASs) are present in aqueous film-forming foams (AFFF) used for firefighting activities. Currently, no single analytical technique provides a complete accounting of total PFASs or total organofluorine co
Externí odkaz:
https://doaj.org/article/770f12d832cd416dab1b82c92fdc2c5a
Autor:
Wesley D. Frey, Anisha Chaudhry, Priscila F. Slepicka, Adam M. Ouellette, Steven E. Kirberger, William C.K. Pomerantz, Gregory J. Hannon, Camila O. dos Santos
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 23-31 (2017)
Chromatin remodeling is a key requirement for transcriptional control of cellular differentiation. However, the factors that alter chromatin architecture in mammary stem cells (MaSCs) are poorly understood. Here, we show that BPTF, the largest subuni
Externí odkaz:
https://doaj.org/article/67eb2c4ce2b741fdab98f03d0c6842ac
Publikováno v:
Molecules, Vol 25, Iss 17, p 3949 (2020)
As fragment-based drug discovery has become mainstream, there has been an increase in various screening methodologies. Protein-observed 19F (PrOF) NMR and 1H CPMG NMR are two fragment screening assays that have complementary advantages. Here, we soug
Externí odkaz:
https://doaj.org/article/7a3dc3b4272f40e8a2cdabf9472d7965
Publikováno v:
Environmental Science & Technology. 57:5327-5336
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b994d0250b35a3a3790ad4db884b4bb
https://doi.org/10.1021/acs.est.3c00627
https://doi.org/10.1021/acs.est.3c00627
Autor:
Damien M. Rasmussen, Manny M. Semonis, Joseph M. Muretta, Andrew R. Thompson, David D. Thomas, William C.K. Pomerantz, Nicholas M. Levinson
Publikováno v:
bioRxiv
Both first-generation αC-out and newer αC-in RAF inhibitors paradoxically activate BRAF kinase at subsaturating concentrations. Paradoxical activation by αC-in inhibitors is linked to the formation of BRAF dimers, but why activation rather than in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be22b6affe409fae8cfbcfc0f229d60
https://doi.org/10.1101/2023.04.18.536450
https://doi.org/10.1101/2023.04.18.536450
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Epigenetic regulators can modulate the effects of cancer therapeutics. To further these observations, we discovered that the bromodomain PHD finger transcription factor subunit (BPTF) of the nucleosome remodeling factor (NURF) promotes resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc0c883ceb3539d71fe27c779f70976
https://doi.org/10.1158/1541-7786.c.6545277.v1
https://doi.org/10.1158/1541-7786.c.6545277.v1
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 5. Selective BPTF Bromdomain Inhibitor AU1 Recapitulates Effects from BPTF KD in Human MDA-MB-231 and Mouse 66cl4 and 4T07 Cell Lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27eee3dab037824eb4c432997801db05
https://doi.org/10.1158/1541-7786.22526982
https://doi.org/10.1158/1541-7786.22526982
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 2. NURF Selectively Suppresses Toxicity to Topoisomerase 2 Poisons and Improves their DNA Damaging Effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14da1f0fee997c059dcc86cd19ec2637
https://doi.org/10.1158/1541-7786.22526991.v1
https://doi.org/10.1158/1541-7786.22526991.v1
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 4. Selective BPTF Bromdomain Inhibitor AU1 Recapitulates Effects from BPTF KD in 4T1 Cells and Tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8a1ae72d220a7e58c080efeb1f9ccb
https://doi.org/10.1158/1541-7786.22526985
https://doi.org/10.1158/1541-7786.22526985
Autor:
Joseph W. Landry, David A. Gewirtz, Yves Pommier, William C.K. Pomerantz, Dipankar Bandyopadhyay, Paula D. Bos, Steve E. Kirberger, Xiaoyan Deng, Ryan Finnegan, Joshua Haueis, Syed Haqqani, Manjulata Singh, Ashish Vaidyanathan, Mallika Dammalapati, Hannah Ngo, Nga Dao, Yilun Sun, Liliya Tyutyunyk-Massey
Supplemental Figure 3. Validation of Autophagy by Microscopy and ATG5 KD in 4T1 Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6cea3399c1394e3e7d959a2f370c44
https://doi.org/10.1158/1541-7786.22526988.v1
https://doi.org/10.1158/1541-7786.22526988.v1