Zobrazeno 1 - 10
of 69
pro vyhledávání: '"William C. Vass"'
Autor:
Douglas R. Lowy, Ana I. Robles, Richard Braverman, Xi Liu, William C. Vass, Aaron J. Schetter, Alex Papageorge, Xiaolan Qian, Xiaoli Du
PDF file - 10.6MB, Mapping the CAV1 interaction to the START domain in the C-terminus of DLC1. The DLC1-Del (929-957) mutant is active in RhoGAP activity in transiently transfected H1299 cells and stably transfected H358 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44adca5c3f0ef95c43192022fc55f657
https://doi.org/10.1158/0008-5472.22395609.v1
https://doi.org/10.1158/0008-5472.22395609.v1
Autor:
Douglas R. Lowy, Ana I. Robles, Richard Braverman, Xi Liu, William C. Vass, Aaron J. Schetter, Alex Papageorge, Xiaolan Qian, Xiaoli Du
PDF file - 1MB, Expression of CAV1 or the combination of low CAV1 with low DLC1 do not affect the prognostic significance of lung cancer patients in Director's challenge cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d48e23a9685936c3c209a1ac1650546
https://doi.org/10.1158/0008-5472.22395603.v1
https://doi.org/10.1158/0008-5472.22395603.v1
Autor:
Douglas R. Lowy, Nicholas C. Popescu, William C. Vass, Xu-Yu Yang, Lyra Olson, Brajendra K. Tripathi, Dunrui Wang, Marian E. Durkin, Xiaolan Qian
PDF file - 304K, Suppl. Table 1: Validated siRNAs used in the current studies Suppl. Fig. 1 Stress fiber formation in MEFs with or without v-Ras expression. Suppl. Fig. 2 The spontaneous transformation is reproducible using another Adeno-Cre treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcde8a1fba00e16c4831ea7f45eb4d81
https://doi.org/10.1158/0008-5472.22394400
https://doi.org/10.1158/0008-5472.22394400
Autor:
Douglas R. Lowy, Nicholas C. Popescu, William C. Vass, Xu-Yu Yang, Lyra Olson, Brajendra K. Tripathi, Dunrui Wang, Marian E. Durkin, Xiaolan Qian
The tumor suppressor gene deleted in liver cancer-1 (DLC1), which encodes a protein with strong RhoGAP (GTPase activating protein) activity and weak Cdc42GAP activity, is inactivated in various human malignancies. Following Dlc1 inactivation, mouse e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d160bdb8d0db77be661194b8ded83740
https://doi.org/10.1158/0008-5472.c.6504021.v1
https://doi.org/10.1158/0008-5472.c.6504021.v1
Autor:
Douglas R. Lowy, Ana I. Robles, Richard Braverman, Xi Liu, William C. Vass, Aaron J. Schetter, Alex Papageorge, Xiaolan Qian, Xiaoli Du
PDF file - 56K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3275c822250cb2ac0d571a68052a1fa6
https://doi.org/10.1158/0008-5472.22395600.v1
https://doi.org/10.1158/0008-5472.22395600.v1
Autor:
Douglas R. Lowy, Ana I. Robles, Richard Braverman, Xi Liu, William C. Vass, Aaron J. Schetter, Alex Papageorge, Xiaolan Qian, Xiaoli Du
PDF file - 4MB, siRNA-mediated reduction of CAV1, DLC1, or both CAV1 and DLC1 increases the migration of H1299 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c94172f0a3a91507720bda834d2759a
https://doi.org/10.1158/0008-5472.22395606
https://doi.org/10.1158/0008-5472.22395606
Autor:
Brajendra K. Tripathi, Nicholas C. Popescu, Xu-Yu Yang, Lyra B. Olson, Douglas R. Lowy, William C. Vass, Dunrui Wang, Marian E. Durkin, Xiaolan Qian
Publikováno v:
Cancer Res
The tumor suppressor gene deleted in liver cancer-1 (DLC1), which encodes a protein with strong RhoGAP (GTPase activating protein) activity and weak Cdc42GAP activity, is inactivated in various human malignancies. Following Dlc1 inactivation, mouse e
Publikováno v:
Proceedings of the National Academy of Sciences. 108:17129-17134
The deleted in liver cancer 1 (DLC1) tumor suppressor gene, which is frequently inactivated in cancer, encodes a Rho-GAP (GTPase activating protein) focal adhesion protein whose negative regulation of Rho-GTPases is necessary but not sufficient for i
Autor:
Douglas R. Lowy, Alex G. Papageorge, Renard C. Walker, Giovanna Tosato, Peter J. Steinbach, Laura Asnaghi, William C. Vass, Xiaolan Qian, Kent W. Hunter, Guorong Li
Publikováno v:
Cancer Cell. 16:246-258
SummaryIn cell lines from advanced lung cancer, breast cancer, and melanoma, endogenous tensin-3 contributes to cell migration, anchorage-independent growth, and tumorigenesis. Although SH2 domains have not been reported previously to be phosphorylat
Autor:
Paul A. Randazzo, Hiroki Inoue, Armand de Gramont, Yvona Ward, Zhongzhen Nie, Sanita Bharti, Vi Luan Ha, Fanny Campa, William C. Vass
Publikováno v:
Journal of Biological Chemistry. 283:14915-14926
ASAP3, an Arf GTPase-activating protein previously called DDEFL1 and ACAP4, has been implicated in the pathogenesis of hepatocellular carcinoma. We have examined in vitro and in vivo functions of ASAP3 and compared it to the related Arf GAP ASAP1 tha