Zobrazeno 1 - 10
of 36
pro vyhledávání: '"William C. Lemon"'
Autor:
Katie McDole, William C. Lemon
Publikováno v:
Current Opinion in Cell Biology. 66:34-42
At the time of this writing, searching Google Scholar for ‘light-sheet microscopy’ returns almost 8500 results; over three-quarters of which were published in the last 5 years alone. Searching for other advanced imaging methods in the last 5 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191e669ffdbb1add33d19c9a46b940db
https://doi.org/10.1016/j.ceb.2020.04.008
https://doi.org/10.1016/j.ceb.2020.04.008
Autor:
Stephan Preibisch, Caroline Malin-Mayor, Katie McDole, Yinan Wan, Philipp J. Keller, William C. Lemon, Jan Funke, Léo Guignard, Peter Hirsch
We present a method for automated nucleus identification and tracking in time-lapse microscopy recordings of entire developing embryos. Our method combines deep learning and global optimization to enable complete lineage reconstruction from sparse po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa01286c9ea7552664338c025175032
https://doi.org/10.1101/2021.07.28.454016
https://doi.org/10.1101/2021.07.28.454016
Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling
Autor:
Marlen Zschätzsch, Carlos Oliva, Marion Langen, Natalie De Geest, Mehmet Neset Özel, W Ryan Williamson, William C Lemon, Alessia Soldano, Sebastian Munck, P Robin Hiesinger, Natalia Sanchez-Soriano, Bassem A Hassan
Publikováno v:
eLife, Vol 3 (2014)
Axonal branching allows a neuron to connect to several targets, increasing neuronal circuit complexity. While axonal branching is well described, the mechanisms that control it remain largely unknown. We find that in the Drosophila CNS branches devel
Externí odkaz:
https://doaj.org/article/a438c93848584e60b9de01501cf0ad54
Publikováno v:
Nature Protocols. 13:2462-2500
We describe the implementation and use of an adaptive imaging framework for optimizing spatial resolution and signal strength in a light-sheet microscope. The framework, termed AutoPilot, comprises hardware and software modules for automatically meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8d9febef6ac0c7b7ef5c612bf4a019
https://doi.org/10.1038/s41596-018-0043-4
https://doi.org/10.1038/s41596-018-0043-4
Autor:
Soomin Kim, Jonathan S. Marvin, William C. Lemon, Haluk Lacin, Jamien Shea, Philipp J. Keller, Richard T. Lee, Loren L. Looger, Minoru Koyama, Jacob P. Keller
Publikováno v:
Cell Reports. 35:109284
Summary Glucose is arguably the most important molecule in metabolism, and its dysregulation underlies diabetes. We describe a family of single-wavelength genetically encoded glucose sensors with a high signal-to-noise ratio, fast kinetics, and affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d5db14e6aeddbee16a59475ddb3af8
https://doi.org/10.1016/j.celrep.2021.109284
https://doi.org/10.1016/j.celrep.2021.109284
Autor:
Loren L. Looger, Minoru Koyama, Philipp J. Keller, William C. Lemon, Jonathan S. Marvin, Richard T. Lee, Jamien Shea, Soomin Kim, Jacob P. Keller, Haluk Lacin
Glucose is arguably the most important molecule in metabolism, and its mismanagement underlies diseases of vast societal import, most notably diabetes. Although glucose-related metabolism has been the subject of intense study for over a century, tool
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a5e77bb3a5f572e5b7e882289fbce2
Autor:
Loren L. Looger, Jacob P. Keller, Haluk Lacin, Soomin Kim, Minoru Koyama, William C. Lemon, Philipp J. Keller, Jamien Shea, Jonathan S. Marvin, Richard T. Lee
Publikováno v:
SSRN Electronic Journal.
Glucose is arguably the most important molecule in metabolism, and its mismanagement underlies diseases of vast societal import, most notably diabetes. Although glucose-related metabolism has been the subject of intense study for over a century, tool
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68556cc7d8743a729c8686485e574bc0
https://doi.org/10.2139/ssrn.3376667
https://doi.org/10.2139/ssrn.3376667
Autor:
Philipp J. Keller, Burkhard Höckendorf, Fernando Amat, Katie McDole, William C. Lemon, Yinan Wan
Publikováno v:
Nature Protocols. 10:1679-1696
Light-sheet microscopy is a powerful method for imaging the development and function of complex biological systems at high spatiotemporal resolution and over long time scales. Such experiments typically generate terabytes of multidimensional image da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8059f7ca3b0f97ef2b700d829537025
https://doi.org/10.1038/nprot.2015.111
https://doi.org/10.1038/nprot.2015.111
Publikováno v:
Biophysical journal. 114(2)
Mechanics plays a key role in the development of higher organisms. However, understanding this relationship is complicated by the difficulty of modeling the link between local forces generated at the subcellular level and deformations observed at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1261073e23472c6053bec05252c8d245
https://pubmed.ncbi.nlm.nih.gov/29401426
https://pubmed.ncbi.nlm.nih.gov/29401426
Autor:
Matej Krajnc, Christine Rushlow, Tomer Stern, Stanislav Y. Shvartsman, Shigehiro Yamada, Philipp J. Keller, Celia M. Smits, Nareg J.-V. Djabrayan, William C. Lemon
Publikováno v:
Current Biology. 29:1193-1198.e5
Summary The thirteen nuclear cleavages that give rise to the Drosophila blastoderm are some of the fastest known cell cycles [ 1 ]. Surprisingly, the fertilized egg is provided with at most one-third of the dNTPs needed to complete the thirteen round
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c46ed2c143c5a16bbb2fd45067b47
https://doi.org/10.1016/j.cub.2019.02.028
https://doi.org/10.1016/j.cub.2019.02.028