Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William C. Hobson"'
Publikováno v:
Antisense Research and Development. 4:201-206
Rapid intravenous infusion of GEM 91, a 25-mer phosphorothioate oligonucleotide complementary to the gag site of HIV, in the monkey produces transient decreases in peripheral total WBC and neutrophil counts, hemoconcentration, and a brief increase fo
Publikováno v:
American Journal of Primatology. 24:257-263
The Primate Research Institute (PRI) dedicated a colony of 81 proven breeders (60 females, 21 males) to the National Chimpanzee Breeding and Research Program (NCBRP). When possible, infants were left with their mothers for a minimum of 18 months. Pro
Autor:
Russell G. Osborn, Francisco I. Reyes, William C. Hobson, M. Ray, James A. Thliveris, Gene B. Fuller, Charles Faiman, Cheryl R. Greenberg
Publikováno v:
American journal of primatologyReferences. 22(1)
A 3-year-old female cynomolgus monkey (Macaca fascicularis) was found to have inappropriately high circulating immunoassayable follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels compatible with primary gonadal failure. Hypergonado
Autor:
William C. Hobson, Gene B. Fuller
Publikováno v:
Biology of Reproduction. 17:294-297
The ability of luteinizing hormone-releaseing hormone (LH-RH; 125 mcg iv) to induce LH and follicle stimulating hormone (FSH) release was studied in 5 male and 11 female chimpanzees. LH peaks were found after LH-RH treatment in all the chimpanzees st
Autor:
Rick J. Schiebinger, Paul T. Turner, Barry D. Albertson, Gordon B. Cutler, William C. Hobson, Richard V. Clark, D. Lynn Loriaux, Belinda S. Burnett
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 59:13-18
We tested the hypothesis that adrenal androgen production is supported by a pituitary factor distinct from ACTH. Six adult male chimpanzees who had completed adrenal maturation (adrenarche) were castrated and either hypophysectomized or sham hypophys
Publikováno v:
Experimental Biology and Medicine. 161:21-24
SummaryThirty-five mg of the LH-RH antagonist (D-Phe6, D-Trp3, D-Phe6)-LH-RH inhibited the LH response of chimpanzees given 10 μg of LH-RH to 33% of the amount released by control animals. Seven mg of the same analog also attenuated the LH response,
Publikováno v:
Experimental Biology and Medicine. 149:670-676
SummaryHeterologous double-antibody radioimmunoassay methods are described for the measurement of circulating levels of rhesus monkey (Macaca mulatto) FSH and LH; the latter assay is also applicable to rhesus chorionic gonadotropin (CG) estimations.
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 40:545-551
Mixed cord sera (27 male, 28 female) and sera from 105 male and 93 female children aged 5 days to 4 yr were assayed for FSH, LH and hCG. Cord hCG was similar in both sexes (median 58 mIU/ml; range 20-9000), and fell to less than 5 mIU/ml by 5 days of
Publikováno v:
The Anatomical Record. 222:245-251
This study was aimed at developing a model in the rhesus monkey for the human gynecologic disorder termed the polycystic ovary syndrome (PCOS). The effects of chronic constant androgen exposure upon quantitative ovarian morphology and ovulatory funct
Publikováno v:
Clinics in Endocrinology and Metabolism. 7:513-530