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pro vyhledávání: '"William C. Hacker"'
Autor:
William C. Hacker, Adrian H. Elcock
Publikováno v:
bioRxiv
Stochastic simulation models have played an important role in efforts to understand the mechanistic basis of prokaryotic transcription and translation. Despite the fundamental linkage of these processes in bacterial cells, however, most simulation mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b8d9ea05da8479cf61bcb0c7846594
https://doi.org/10.1101/2023.04.21.537861
https://doi.org/10.1101/2023.04.21.537861
Publikováno v:
Nucleic Acids Research
We describe structural models of the Escherichia coli chromosome in which the positions of all 4.6 million nucleotides of each DNA strand are resolved. Models consistent with two basic chromosomal orientations, differing in their positioning of the o
Autor:
Wesley K. Lay, Adrian H. Elcock, Jianlan Ren, Shuxiang Li, Jiadi An, Mark S. Miller, William C. Hacker
Publikováno v:
Journal of chemical theory and computation. 13(4)
There is a small, but growing, body of literature describing the use of osmotic coefficient measurements to validate and reparameterize simulation force fields. Here we have investigated the ability of five very commonly used force field and water mo