Zobrazeno 1 - 10
of 105
pro vyhledávání: '"William C. Engeland"'
Autor:
Maria Razzoli, Angus Lindsay, Michelle L. Law, Christopher M. Chamberlain, William M. Southern, Madeleine Berg, John Osborn, William C. Engeland, Joseph M. Metzger, James M. Ervasti, Alessandro Bartolomucci
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: Duchenne muscular dystrophy (DMD) is caused by the loss of dystrophin. Severe and ultimately lethal, DMD progresses relatively slowly in that patients become wheelchair bound only around age twelve with a survival expectancy reaching the
Externí odkaz:
https://doaj.org/article/67a91b5560474402bcbe5aa9b03fbaf4
Autor:
Paulo Kofuji, Ludovic S Mure, Logan J Massman, Nicole Purrier, Satchidananda Panda, William C Engeland
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168651 (2016)
Light is a powerful entrainer of circadian clocks in almost all eukaryotic organisms promoting synchronization of internal circadian rhythms with external environmental light-dark (LD) cycles. In mammals, the circadian system is organized in a hierar
Externí odkaz:
https://doaj.org/article/51cba36c7db84f7181b6206f12ee663c
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111449 (2014)
Several aspects of behavior and physiology, such as sleep and wakefulness, blood pressure, body temperature, and hormone secretion exhibit daily oscillations known as circadian rhythms. These circadian rhythms are orchestrated by an intrinsic biologi
Externí odkaz:
https://doaj.org/article/1f1c6cd1b58e4d92825d6a8bbb9fd356
Autor:
Emanuele Pignatti, William C. Engeland, David T. Breault, Mary E. Piper, Sining Leng, Paulo Kofuji, Shubhendu Mishra, Diana L. Carlone, Logan Massman, J. Marina Yoder
Publikováno v:
Endocrinology. 159:3950-3964
The glucocorticoid (GC) rhythm is entrained to light-dark (LD) cycles via a molecular clock in the suprachiasmatic nucleus (SCN) and is maintained by an adrenal clock synchronized by SCN-dependent signals. Targeted deletion of the core clock gene Bma
Autor:
Joseph M. Metzger, Christopher M. Chamberlain, Madeleine Berg, William C. Engeland, Alessandro Bartolomucci, Angus Lindsay, Maria Razzoli, John W. Osborn, Michelle L. Law, James M. Ervasti, William M. Southern
Publikováno v:
EBioMedicine, Vol 55, Iss, Pp-(2020)
EBioMedicine
EBioMedicine
Background Duchenne muscular dystrophy (DMD) is caused by the loss of dystrophin. Severe and ultimately lethal, DMD progresses relatively slowly in that patients become wheelchair bound only around age twelve with a survival expectancy reaching the t
Autor:
David T. Breault, Sining Leng, Paulo Kofuji, Diana L. Carlone, William C. Engeland, Emanuele Pignatti, Logan Massman, Lorena Pantano, Lauren Miller
Publikováno v:
Endocrinology
The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock that is synchronized by the SCN. To determine whether the adrenal clock modulates GC responses to stress, experiments
Autor:
William C. Engeland, Carley A. Karsten, Maria Razzoli, Alessandro Bartolomucci, J. Marina Yoder
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 307:R198-R205
Circadian rhythms in glucocorticoids are the product of interactions between the hypothalamic-pituitary-adrenal (HPA) axis and the mammalian clock gene system. The adrenal clock can generate the glucocorticoid rhythm that in turn synchronizes other p
Publikováno v:
Frontiers in Endocrinology
The adrenal cortex has a molecular clock that generates circadian rhythms in glucocorticoid production, yet it is unclear how the clock responds to acute stress. We hypothesized that stress-induced ACTH provides a signal that phase shifts the adrenal
Autor:
William C. Engeland, Logan Massman, Paulo Kofuji, Ludovic S. Mure, Nicole Purrier, Satchidananda Panda
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168651 (2016)
PLoS ONE
PLoS ONE
Light is a powerful entrainer of circadian clocks in almost all eukaryotic organisms promoting synchronization of internal circadian rhythms with external environmental light-dark (LD) cycles. In mammals, the circadian system is organized in a hierar
Publikováno v:
Endocrinology. 151:4852-4860
The adrenal zona glomerulosa (ZG) secretes aldosterone to regulate sodium balance. Chronic sodium restriction increases aldosterone accompanied by ZG expansion. The ZG is innervated by sympathetic, vasoactive intestinal polypeptide (VIP) and neuropep