Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William C Valinsky"'
Autor:
Chandima Bulumulla, Andrew T Krasley, Ben Cristofori-Armstrong, William C Valinsky, Deepika Walpita, David Ackerman, David E Clapham, Abraham G Beyene
Publikováno v:
eLife, Vol 11 (2022)
Chemical neurotransmission constitutes one of the fundamental modalities of communication between neurons. Monitoring release of these chemicals has traditionally been difficult to carry out at spatial and temporal scales relevant to neuron function.
Externí odkaz:
https://doaj.org/article/4a2fa60da74749aca50297935f2eef29
Autor:
Shuai, Gao, William C, Valinsky, Nguyen Cam, On, Patrick R, Houlihan, Qian, Qu, Lei, Liu, Xiaojing, Pan, David E, Clapham, Nieng, Yan
Publikováno v:
Proc Natl Acad Sci U S A
NaChBac, the first bacterial voltage-gated Na(+) (Na(v)) channel to be characterized, has been the prokaryotic prototype for studying the structure–function relationship of Na(v) channels. Discovered nearly two decades ago, the structure of NaChBac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bd233d2e68d1ca51c2fd4f667e5a84d
https://pubmed.ncbi.nlm.nih.gov/32513729
https://pubmed.ncbi.nlm.nih.gov/32513729
Autor:
Lei Liu, Nieng Yan, Xiaojing Pan, David E. Clapham, Patrick R. Houlihan, Qian Qu, Shuai Gao, Nguyen Cam On, William C. Valinsky
NaChBac, the first bacterial voltage-gated Na + (Na v ) channel to be characterized, has been the prokaryotic prototype for studying the structure–function relationship of Na v channels. Discovered nearly two decades ago, the structure of NaChBac h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eaf3ba4b1bb6642bcb9a1ac3378b08c
https://doi.org/10.1101/2020.04.16.045674
https://doi.org/10.1101/2020.04.16.045674
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 315:G592-G601
We have previously demonstrated that satiety sensing vagal afferent neurons are less responsive to meal-related stimuli in obesity because of reduced electrical excitability. As leak K+ currents are key determinants of membrane excitability, we hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057b96f399707d73cb122954d0ebd310
https://doi.org/10.1152/ajpgi.00335.2017
https://doi.org/10.1152/ajpgi.00335.2017
Publikováno v:
Vitamins and hormones. 109
Since its discovery, aldosterone and ion modulation have been entwined. While scientific investigations throughout the decades have emphasized aldosterone's connection to Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3fa0088b6d977adec30008de2924cf2
https://pubmed.ncbi.nlm.nih.gov/30678852
https://pubmed.ncbi.nlm.nih.gov/30678852
Since its discovery, aldosterone and ion modulation have been entwined. While scientific investigations throughout the decades have emphasized aldosterone's connection to Na+, K+, and H+ homeostasis, more recent research has demonstrated a relationsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a49160dcaf9ea8e5551dee941c35ffdb
https://doi.org/10.1016/bs.vh.2018.10.004
https://doi.org/10.1016/bs.vh.2018.10.004
Autor:
William C. Valinsky, Brian Foo, Alvin Shrier, Camille Barbier, Gergely L. Lukacs, Josua Solomon, Jeeventh Kaur, Elya Quesnel
Publikováno v:
Biophysical Journal. 118:110a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561ff34f8afe56b4ef483683c1910996
https://doi.org/10.1016/j.bpj.2019.11.751
https://doi.org/10.1016/j.bpj.2019.11.751
Autor:
Alvin Shrier, Brittany Williamson, Joshua Solomon, William C. Valinsky, Christine Hantouche, Jason C. Young
Cardiac long QT syndrome type 2 is caused by mutations in the human ether a go-go-related gene (hERG) potassium channel, many of which cause misfolding and degradation at the endoplasmic reticulum instead of normal trafficking to the cell surface. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e551eb24b17af67928dd852f216f73b
https://europepmc.org/articles/PMC5313101/
https://europepmc.org/articles/PMC5313101/
Autor:
Brian Foo, William C. Valinsky, Tsukasa Okiyoneda, Pirjo M. Apaja, Roxana Atanasiu, Gergely L. Lukacs, Herve Barriere, Eckhard Ficker, Alvin Shrier
Publikováno v:
Molecular Biology of the Cell
The role of the plasma membrane quality control machinery is demonstrated in the development of the long QT syndrome phenotype, caused by acquired and inherited conformational defects of the hERG potassium channel in multiple expression systems, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fa336a3a240f960d8b09cb1a0b501b
https://doi.org/10.1091/mbc.e13-07-0417
https://doi.org/10.1091/mbc.e13-07-0417
Autor:
Andreas Kompatscher, Jeroen H. F. de Baaij, Michel L. Tremblay, Joost G. J. Hoenderop, Alvin Shrier, Elie Kostantin, Noriko Uetani, William C. Valinsky, Luis Alfonso Martínez-Cruz, Melissa Landry, Yevgen Zolotarov, Serge Hardy
Publikováno v:
Journal of Biological Chemistry, 291, 10716-25
Journal of Biological Chemistry, 291, 20, pp. 10716-25
The Journal of Biological Chemistry
Journal of Biological Chemistry, 291, 20, pp. 10716-25
The Journal of Biological Chemistry
Contains fulltext : 167310.pdf (Publisher’s version ) (Open Access) The oncogenic phosphatase of regenerating liver 2 (PRL-2) has been shown to regulate intracellular magnesium levels by forming a complex through an extended amino acid loop present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb8de10a6b3f5b726e194b2f7b025b1
http://hdl.handle.net/2066/167310
http://hdl.handle.net/2066/167310