Zobrazeno 1 - 10
of 39
pro vyhledávání: '"William C, Hartner"'
Autor:
Salome Siavoshi, Ahmed Busnaina, Jaydev R. Upponi, William C. Hartner, Tiziana Musacchio, Asanterabi Malima, Sivasubramanian Somu, Vladimir P. Torchilin, Cihan Yilmaz, Tatyana S. Levchenko
Biomarkers are emerging as potentially important diagnostic tools for cancer and many other diseases. However, many current detection systems for suffer from insufficient sensitivity. To address this concern, we developed a highly sensitive biosensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563fd8517a45133e0529fcf796b147da
https://doi.org/10.21203/rs.3.rs-238414/v1
https://doi.org/10.21203/rs.3.rs-238414/v1
Autor:
Sara Bersani, Mónica Vermeulen, Tiziana Musacchio, Francesca Mastrotto, Vladimir P. Torchilin, Valeria Quattrocchi, William C. Hartner, Micaela Toniutti, Patricia Ines Zamorano, Tatyana S. Levchenko, Federica Ghersa, Cecilia Langellotti, Stefano Salmaso, Juan Sebastian Pappalardo
Dendritic cells serve as the main immune cells that trigger the immune response. We developed a simple and cost-effective nanovaccine platform based on the α1',2-mannobiose derivative for dendritic cell targeting. In previous work, we have formulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9997106746bc94f6e7e03eb338bb2d85
http://hdl.handle.net/11577/3398426
http://hdl.handle.net/11577/3398426
Autor:
Bhushan S. Pattni, Srikar G. Nagelli, Bhawani Aryasomayajula, Pranali P. Deshpande, Abhijit Kulkarni, William C. Hartner, Ganesh Thakur, Alexei Degterev, Vladimir P. Torchilin
Publikováno v:
Pharmaceutical research. 33(10)
To develop transferrin (Tf)-targeted delivery systems for the pro-apoptotic drug, NCL-240, and to evaluate the efficacy of this delivery system in ovarian cancer NCI/ADR-RES cells, grown in vitro in a 3D spheroid model.Tf-targeted PEG-PE-based micell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83117638be6dccaa34947c17d4429e03
https://pubmed.ncbi.nlm.nih.gov/27599990
https://pubmed.ncbi.nlm.nih.gov/27599990
Publikováno v:
Therapeutic Delivery. 3:501-514
Liposome-based pharmaceuticals used within the cardiovascular system are reviewed in this article. The delivery of diagnostic and therapeutic agents by plain liposomes and liposomes with surface-attached targeting antibodies or polyethylene glycol to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e10f21591b00abc8a748d7a6bcf031
https://doi.org/10.4155/tde.12.18
https://doi.org/10.4155/tde.12.18
Autor:
Tatyana S. Levchenko, Vladimir P. Torchilin, Daya D. Verma, Eugene A. Bernstein, William C. Hartner
Publikováno v:
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 1:530-539
A major obstacle to drug therapy for treatment of potential myocardial infarction is the limited access to the ischemic myocardium by drugs in an active form. Encouraging results have been reported with liposomes loaded with ATP in a variety of in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e451a762710dafcea897048c82c2ee
https://doi.org/10.1002/wnan.46
https://doi.org/10.1002/wnan.46
Autor:
Vladimir P. Torchilin, Aristarchos Papagiannaros, Dmitry A. Mongayt, Tatyana S. Levchenko, William C. Hartner
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 5:216-224
Near-infrared (NIR) whole-body imaging is a powerful noninvasive method for the visualization of complex biological phenomena such as tumor and tumor vasculature and for whole-body studies. In this study we introduced a new NIR contrast agent in poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffca6c825bfb70f30e998222358081a
https://doi.org/10.1016/j.nano.2008.10.001
https://doi.org/10.1016/j.nano.2008.10.001
Autor:
Vladimir P. Torchilin, William C. Hartner, Young Tag Ko, Brigitte Papahadjopoulos-Sternberg, Amit Kale
Publikováno v:
Journal of Controlled Release. 133:132-138
With few exceptions, where local administration is feasible, progress towards broad clinical application of gene therapies requires the development of effective delivery systems. Here we report a novel non-viral gene delivery vector, ‘micelle-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf6a4b09e3d4ae27a09db203bebea9e
https://doi.org/10.1016/j.jconrel.2008.09.079
https://doi.org/10.1016/j.jconrel.2008.09.079
Autor:
Tatyana S. Levchenko, Daya D. Verma, William C. Hartner, Vineet Thakkar, Vladimir P. Torchilin
Publikováno v:
Pharmaceutical Research. 24:2131-2137
We assessed whether the infusion of Coenzyme Q10-loaded liposomes (CoQ10-L) in rabbits with an experimental myocardial infarction can result in increased intracellular delivery of CoQ10 and thus limit the fraction of the irreversibly damaged myocardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7081fa5c9c678fc0781aefc3d1468db2
https://doi.org/10.1007/s11095-007-9334-0
https://doi.org/10.1007/s11095-007-9334-0
Publikováno v:
Journal of Controlled Release. 120:35-40
Preservation of cell viability using Cytoskeletal-antigen Specific ImmunoLiposomes (antimyosin-CSIL) has been demonstrated in cell cultures. The current study utilized the same CSIL intervention for myocardial protection in an in vivo rabbit model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2ecd8bf19adedd2fffa0284c346a989
https://doi.org/10.1016/j.jconrel.2007.04.013
https://doi.org/10.1016/j.jconrel.2007.04.013
Autor:
Daya D. Verma, Eugene A. Bernstein, Tatayana S. Levchenko, Vladimir P. Torchilin, William C. Hartner
Publikováno v:
Pharmaceutical Research. 22:2115-2120
We assessed whether the infusion of ATP-loaded liposomes (ATP-L) can limit the fraction of the irreversibly damaged myocardium in rabbits with an experimental myocardial infarction. ATP-L, empty liposomes (EL), or Krebs–Henseleit (KH) buffer were a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6904b4ebb1a0742b4793d1986bab0b
https://doi.org/10.1007/s11095-005-8354-x
https://doi.org/10.1007/s11095-005-8354-x