Zobrazeno 1 - 10
of 39
pro vyhledávání: '"William Bush"'
Autor:
Hung-Hsin Chen, Lauren E. Petty, Jin Sha, Yi Zhao, Amanda Kuzma, Otto Valladares, Alzheimer’s Disease Genetics Consortium, International Genomics of Alzheimer’s Project, William Bush, Adam C. Naj, Eric R. Gamazon, Jennifer E. Below
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Late-onset Alzheimer disease (LOAD) is highly polygenic, with a heritability estimated between 40 and 80%, yet risk variants identified in genome-wide studies explain only ~8% of phenotypic variance. Due to its increased power and interpreta
Externí odkaz:
https://doaj.org/article/0f502839818045e6bbdef11e4cc55717
Autor:
Puneet Bhargava, Adeel Seyal, Chandana Lall, Mariam Moshiri, Jennifer Schopp, Jennifer Favinger, Carolyn Wang, Neeraj Lalwani, Martin Gunn, William Bush
Publikováno v:
MedEdPORTAL, Vol 9 (2013)
Abstract Radiologists supervising imaging studies using contrast media should have the necessary knowledge and skills to deal with adverse contrast media reactions and their appropriate management. The aim of this curriculum is to educate practicing
Externí odkaz:
https://doaj.org/article/f72886a482c74a2cbb5f494a5803aaee
Autor:
Douglas William Bush
Publikováno v:
Chiricú Journal: Latina/o Literatures, Arts, and Cultures. 4:199-202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edc49336552ffc9060e530b58dec47d
https://doi.org/10.2979/chiricu.4.2.23
https://doi.org/10.2979/chiricu.4.2.23
Autor:
Badri N, Vardarajan, Dolly, Reyes-Dumeyer, Angel L, Piriz, Rafael A, Lantigua, Martin, Medrano, Diones, Rivera, Ivonne Z, Jiménez-Velázquez, Eden, Martin, Margaret A, Pericak-Vance, William, Bush, Lindsay, Farrer, Jonathan L, Haines, Li-San, Wang, Yuk Yee, Leung, Gerard, Schellenberg, Walter, Kukull, Philip, De Jager, David A, Bennett, Julie A, Schneider, Richard, Mayeux
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 18(12)
Progranulin (GRN) mutations occur in frontotemporal lobar degeneration (FTLD) and in Alzheimer's disease (AD), often with TDP-43 pathology.We determined the frequency of rs5848 and rare, pathogenic GRN mutations in two autopsy and one family cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66602b44148e6db9915cde774896e13d
https://pubmed.ncbi.nlm.nih.gov/35258170
https://pubmed.ncbi.nlm.nih.gov/35258170
Publikováno v:
Journal of the American Veterinary Medical Association. 255:55-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae5a48b338e90823916621c028e3193
https://doi.org/10.2460/javma.255.1.55
https://doi.org/10.2460/javma.255.1.55
Modeling Transcriptional Regulation Using Gene Regulatory Networks Based on Multi-Omics Data Sources
Autor:
Neel Patel, William Bush
BackgroundTranscriptional regulation is complex, requiring multiple cis(local) and trans acting mechanisms working in concert to drive gene expression, with disruption of these processes linked to multiple diseases. Previous computational attempts to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::441eff5b7525e56a4394c068eefc8a05
https://doi.org/10.21203/rs.3.rs-112300/v1
https://doi.org/10.21203/rs.3.rs-112300/v1
Autor:
Harpreet Kaur, Robert Kalayjian, Kunling Wu, Katherine Tassiopoulos, Frank Palella, Babafemi Taiwo, William Bush, Corrilynn Hileman, Roger Bedimo, Susan Koletar, Ronald Ellis, Kristine Erlandson, Asha Kallianpur
Publikováno v:
The Lancet Healthy Longevity. 3:S5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a3dac88f492cdff8a735786fe938ed
https://doi.org/10.1016/s2666-7568(22)00066-6
https://doi.org/10.1016/s2666-7568(22)00066-6
Autor:
William Bush, Claude Gendre
Publikováno v:
Francis Poulenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ca9d87503466f79a6f40bf276c09ed
https://doi.org/10.4324/9781315093956-12
https://doi.org/10.4324/9781315093956-12
Autor:
Weixin Wang, Li (Charlie) Xia, Alejandro Nato, D Kalra, Claudia L Satizabal, Mohammad Arfan Ikram, Yuk Yee Leung, Kathryn Lunetta, Jaeyoon Chung, Kim Worley, Elizabeth Blue, Cornelia Van Duijn, Yuning Chen, Sudha Seshadri, Congcong Zhu, William Bush, Yeunjoo Song
Publikováno v:
Alzheimer's and Dementia, 15(3), 441-452. Elsevier
Zhang, X, Zhu, C, Beecham, G, Vardarajan, B N, Ma, Y, Lancour, D, Farrell, J J, Chung, J, Alzheimer's Disease Sequencing Project, Mayeux, R, Haines, J L, Schellenberg, G D, Pericak-Vance, M A, Lunetta, K L & Farrer, L A 2019, ' A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease ', Alzheimer's and Dementia, vol. 15, no. 3, pp. 441-452 . https://doi.org/10.1016/j.jalz.2018.10.005
Zhang, X, Zhu, C, Beecham, G, Vardarajan, B N, Ma, Y, Lancour, D, Farrell, J J, Chung, J, Alzheimer's Disease Sequencing Project, Mayeux, R, Haines, J L, Schellenberg, G D, Pericak-Vance, M A, Lunetta, K L & Farrer, L A 2019, ' A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease ', Alzheimer's and Dementia, vol. 15, no. 3, pp. 441-452 . https://doi.org/10.1016/j.jalz.2018.10.005
Introduction The genetic architecture of Alzheimer's disease (AD) is only partially understood. Methods We conducted an association study for AD using whole sequence data from 507 genetically enriched AD cases (i.e., cases having close relatives affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc9860fbb165b21f9e5e744a9dd31b9
https://ora.ox.ac.uk/objects/uuid:66b506a6-9f82-4eba-93a9-1f030e0d0cb4
https://ora.ox.ac.uk/objects/uuid:66b506a6-9f82-4eba-93a9-1f030e0d0cb4
Autor:
Dana Horáková, Matthew S. Gillman, Nicholas Wood, Colin Palmer, Vincent Damotte, Robert Plomin, Pierre-Antoine Gourraud, Sergio Baranzini, Céline Bellenguez, Finn Sellebjerg, Loukas Moutsianas, Panos Deloukas, Ingrid Kockum, Christopher George Mathew, Jim Stankovich, Frauke Zipp, Steffan Daniel Bos, Janna Saarela, Mohamed EL BEHI, Nikolaos Patsopoulos, William Bush, An Goris, Manuel Comabella Lopez, Tomas Olsson
Publikováno v:
Genes & Immunity. 15:126-132
Genome-wide association studies (GWASs) perform per-SNP association tests to identify variants involved in disease or trait susceptibility. However, such an approach is not powerful enough to unravel genes that are not individually contributing to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81dcc558d8274e0dd8c14fa50b7f9ff6
https://doi.org/10.1038/gene.2013.70
https://doi.org/10.1038/gene.2013.70