Zobrazeno 1 - 10
of 84
pro vyhledávání: '"William Bondareff"'
Autor:
William Bondareff
Publikováno v:
Journal of Alzheimer's Disease. 35:1-6
Alzheimer's disease is a neurodegenerative disease in which aging is not only a major risk factor but a major determinant of onset, course, and pathogenesis. The synthesis of amyloid-β (Aβ) peptides by neurons and their excretion into the extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d307d76a5f34045d54696ef244c22e
https://doi.org/10.3233/jad-122305
https://doi.org/10.3233/jad-122305
Autor:
Ralph Green, Peggy S. Gott, Kathy Cairo, Ralph Carmel, Victor W. Henderson, Christopher M. DeGiorgio, William Bondareff, Donald W. Jacobsen, Jeffrey L. Cummings, Galen Buckwalter, Cheryl H. Waters
Publikováno v:
European Journal of Haematology. 54:245-253
Cobalamin levels are frequently low in patients with dementia, but it is unclear if they represent definable deficiency and what the mechanisms are. Therefore, patients being evaluated for dementia who had low cobalamin levels but no obvious evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de52d0f6762d9c7066144840d6bb6777
https://doi.org/10.1111/j.1600-0609.1995.tb00679.x
https://doi.org/10.1111/j.1600-0609.1995.tb00679.x
Autor:
Helen Wilton-Cox, Mary R. Cairns, Jonathan H. Dowson, William Bondareff, Christopher Q. Mountjoy
Publikováno v:
Journal of Alzheimer's Disease. 1:71-79
Cerebellar tissue was examined from 22 patients with Alzheimer's disease (AD) and from an age-matched group of 20 non-diseased subjects. Intraneuronal lipopigment in the bodies of 1344 Purkinje cells (PCs) (32 per brain) was identified by fluorescenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e31f7cab6c1c11afce1d19e3ec75579
https://doi.org/10.3233/jad-1998-1201
https://doi.org/10.3233/jad-1998-1201
Publikováno v:
Journal of Neuroscience Research. 52:498-504
Neuron-like cells derived from a rat pheochromocytoma cell line (PC12) and differentiated with nerve growth factor produce a paired helical filament (PHF)-like antigen when they are subjected to heat shock (Wallace et al.: Mol Brain Res 19:149-155, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b41770a37cb8bdebee2540d8730bbc74
https://doi.org/10.1002/(sici)1097-4547(19980601)52:5<498::aid-jnr2>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19980601)52:5<498::aid-jnr2>3.0.co
Autor:
Martin Roth, Douglas L. Hauser, Claude Michel Wischik, Charles R. Harrington, William Bondareff
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 54:657-663
Adult human nerve cells contain tau protein, a phosphorylated microtubule-associated protein, that is hyperphosphorylated in the fetus and in patients with Alzheimer's disease. Hyperphosphorylation, which diminishes the microtubule-binding capacity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640b47503ed9345be4a4c10d300de2cf
https://doi.org/10.1097/00005072-199509000-00007
https://doi.org/10.1097/00005072-199509000-00007
Publikováno v:
International Review of Psychiatry. 7:293-297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d53fc513761bb0b507ca643bfcba1e4
https://doi.org/10.3109/09540269509022984
https://doi.org/10.3109/09540269509022984
Autor:
Steven S. Matsuyama, William Bondareff
Publikováno v:
International Review of Psychiatry. 7:349-360
SummaryDementia in Alzheimer's disease is associated closely with the accumulation of hyperpkosphorylated, C-terminally truncated tau protein. It is accumulated, in part, into paired helical filaments (PHF) which form the neurofibrillary tangles char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b583393e5fb18121d93f64f9093f92ce
https://doi.org/10.3109/09540269509022987
https://doi.org/10.3109/09540269509022987
Autor:
William Bondareff, Steven S. Matsuyama
Publikováno v:
Journal of Neuroscience Research. 39:519-524
The presence of the microtubule-associated protein tau in skin fibroblasts derived from Alzheimer patients and normal controls was investigated using a panel of well-characterized anti-tau antibodies against epitopes spanning the tau protein from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72722124ae115e6e4cc99f6a8c23bba
https://doi.org/10.1002/jnr.490390503
https://doi.org/10.1002/jnr.490390503
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 53:158-164
Antibodies to different phosphorylated and non-phosphorylated tau epitopes have been used to identify three histologically distinct types of neurofibrillary tangles in Alzheimer's disease. Intracellular tangles (Type 1) were identified by antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432b61506c49b2b733d92cfd5f6074c5
https://doi.org/10.1097/00005072-199403000-00007
https://doi.org/10.1097/00005072-199403000-00007
Autor:
Steven S. Matsuyama, M. Mandelkern, Robert B. Lufkin, Gary W. Small, Andrew F. Leuchter, Asenath La Rue, William Bondareff, Lissy F. Jarvik, Anna Okonek
Publikováno v:
Archives of Neurology. 50:209-219
• Objective. —The study of monozgotic twins can elucidate possible environmental causes for a disease in genetically identical subjects. To this end, we studied a pair of monozygotic female twins appearing discordant for dementia of the Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aa9a3501b1e4367d6c9637966984354
https://doi.org/10.1001/archneur.1993.00540020085022
https://doi.org/10.1001/archneur.1993.00540020085022